Bio-tools for the Future International 2-year Bioinformatics - - PowerPoint PPT Presentation

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Bio-tools for the Future International 2-year Bioinformatics - - PowerPoint PPT Presentation


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SLIDE 1
  • Bio-tools for the Future

International 2-year Bioinformatics Master’s Programme

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SLIDE 2
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SLIDE 3
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SLIDE 6

Two MSC Internships:

  • Major (36 – 42 ECTS)
  • Minor (18 – 24 ECTS)
  • Extra 6 ECTS for scientific report writing and giving

end seminars for both the major and minor projects

  • projects

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SLIDE 7

Colloquium series and writing research proposal (6 ects)

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SLIDE 8
  • 1. Most courses are organised on a half-time basis as

they typically take two months for 6 ects.

  • 2. Courses do not involve many fixed contact hours:

typically two 2-hour lectures per week

  • 3. Courses involve assignments, varying from question

sheets to scientific mini-projects, that you will need to report on. We have an open door policy in the

  • report on. We have an open door policy in the

bioinformatics group for this, and we expect you to come to us with all your queries (private tuition).

  • 4. Together this means there is a lot of flexibility for you

to arrange your bioinformatics master’s.

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SLIDE 9

7 7 7 7 Our MSc Bioinformatics students have visited:

  • Other Dutch Centres:

CMBI, UMC, UvA, MRC-Holland

  • Foreign Centres:

Sloan Kettering Foundation NYC,

  • Oakland, NZ

Stockholm Bioinformatics Centre INRIA Strasbourg RIKEN Tokyo, Japan

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SLIDE 10

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SLIDE 11

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  • A single area of deficiency (e.g. programming) can be
  • A single area of deficiency (e.g. programming) can be

brought up to scratch during the master by attending courses such as:

  • Course ‘Inleiding programmeren’
  • Course Molecular Biology and Genetics

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SLIDE 12

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  • – Molecular Biology

– Pharmacology (drug design) – Agriculture – Biotechnology – Clinical medicine

  • – Clinical medicine

– Anthropology – Forensic science – Chemical industries (detergent industries, etc.) Excellent job opportunities

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SLIDE 13

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SLIDE 14

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SLIDE 15

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  • The Centre for Integrative

Bioinformatics (IBIVU)

Faculty of Sciences Faculteit of Earth and Life Sciences

  • Faculteit of Earth and Life Sciences

VU Medical Centre (VUMC)

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SLIDE 16

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Partners at VU:

Institute for Molecular Cell Biology (Systems Biology) Center for Neurogenomics and Cognitive Research Center for research on Biocomplex Systems

  • Center for research on Biocomplex Systems

VUMC Oncoproteomics Laboratory VUMC Microarray Core Facility

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SLIDE 17

Partners in large (inter)national projects:

Centre for Medical Systems Biology Ecogenomics Netherlands Bioinformatics Centre

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  • Netherlands Bioinformatics Centre

EU Network of Excellence “ENFIN”

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SLIDE 18
  • Interdisciplinary
  • Core Bioinformatics group (enabling

technologies/Tools directed)

  • Systems Biology/Genomics/Neurobiology

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  • Systems Biology/Genomics/Neurobiology
  • Mathematics/Computer Science
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SLIDE 19

Some of our research projects:

  • Multiple sequence alignment of TM proteins
  • Protein-Protein interaction prediction
  • Protein function discriminating site prediction

(Sequence Harmony, Multi-RELIEF)

  • Fluxomics
  • Evolutionary fuzzy clustering of aCGH and Ecogenomics

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  • Evolutionary fuzzy clustering of aCGH and Ecogenomics

data

  • Analysis of proteomics mass spectrometry data
  • RNA evolutionary analysis and structure prediction
  • Systems Biology of Altzheimer’s disease
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SLIDE 20

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SLIDE 21

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SLIDE 22

* * * *

Mathematics Statistics Biology Molecular biology Chemistry

Bioinformatics

  • Computer

Science Informatics Medicine Physics

Bioinformatics

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SLIDE 23

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  • “The big bang” -- 26 June 2000 – announcing

the human genome

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SLIDE 24

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This is a microarray measuring the expression of many genes in one experiment

  • experiment
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SLIDE 25

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Genome Expressome

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  • TERTIARY STRUCTURE (fold)

TERTIARY STRUCTURE (fold)

Proteome Metabolome

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SLIDE 26

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Genome Expressome

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  • TERTIARY STRUCTURE (fold)

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Proteome Metabolome

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SLIDE 27

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