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Bahrami Children Hospital Tehran University of Medical Sciences Thrombosis in Wilm s Tumor M.A.Ehsani Pediatrician,Hem.&Onc. Bahrami Hospital Tehran university of Medical Sciences XII IPHOS Congress 1398/6/27 Urmia


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Bahrami Children Hospital

Tehran University of Medical Sciences

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Thrombosis in Wilm’s Tumor

M.A.Ehsani

Pediatrician,Hem.&Onc. Bahrami Hospital Tehran university of Medical Sciences XII –IPHOS Congress 1398/6/27 Urmia

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Introduction:

  • Wilm's tumor and renal cell

carcinoma are the most common of renal thrombosis.

  • lymphomas, primary renal Burkitt

lymphoma (BL) is rare.

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  • Surgery is the most

prognostic factor in Wilm's tumor

  • utcome.
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Case1:

  • 7 years old girl
  • Abdominal mass in July

2009(Mordad1388).

  • Tumor thrombi was extend from right

kidney to renal vein, inferior vena cava, right atrium and present in right ventricle.

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Case1( Continue):

  • The kidney biopsy is done on 19th August 2009

(1388/05/28).

  • Pathology report was Wilm’s tumor Favorable

histology.

  • Protocol NWTS-4( D-4A) was began.
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Case1( Continue):

  • Total right nephrectomy and thrombectmy

was performed on19th October 2009(1388/07/27) with coupling of Pediatric surgeon and Heart Surgeon.

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Case1( Continue):

  • Radiotherapy and chemotherapy continued

till 26th September 2010( 1389/07/04).

  • At present the patient is free of tumor
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Case2:

  • A 4 years old boy who referred with clot in

urine and fever was admitted as UTI.

  • Left renal mass is detected with renal vein

thrombosis.

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Case2( Continue):

  • Total left nephrectomy and thrombectmy

was performed on7th July 2017(1396/04/16) with coupling of Pediatric surgeon and Vascular Surgeon.

  • Protocol NWTS-4( D-4A) was began at the

time of

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Case2( Continue):

  • The first Pathology report was Renal Cell

Carcinoma.

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Case2( Continue):

  • The first Pathology report was Renal Cell

Carcinoma.

  • The review of Pathology report was Wilm’s

tumor Rhabdoid type (Unfavorable histology).

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Case2( Continue):

  • After the pathology report the ICE and

VDC protocol substituted.

  • Chemotherapy continued till 7th May 2018

(1397/2/17).

  • At present the patient is free of tumor.
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Case3:

  • A 2.5 years old boy who referred with Left

abdominal mass.

  • Tumor thrombi was extend from right

kidney to renal vein, inferior vena cava, right atrium .

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Case3( Continue):

  • مکش یفارگونوس شرازگ:
  • لقادح داعبا اب گرزب رایسب هدوت(129رد95رتمیلیم )

لحم زا هک کیتسیس تارییغت یواح نژورته دیلاس ا هتفای شرتسگ نگل تمس هب پچ هیلک کیموتانآ و تس چ هیلک یناتحت لپ میشناراپ زا یشخب نآ رانک رد هدید پ دوشیم.

  • ب شرتسگ اب یناتحت فوجا دیرو لاروموت زوبمورت ه

دوشیم تیور تسار زیلهد.

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Case3( Continue):

  • Total left nephrectomy was performed
  • n14th April 2019(1398/1/25).
  • Pathology report was Wilm’s tumor

favorable histology.

  • High risk Wilm's tumor protocol was began

at the time of nephrectomy.

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Case3( Continue):

  • After nephrectomy, massive ascitis and

pleural effusion and hypo-albuminemia were present which did not response to albumin administration.

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Case3( Continue):

  • Total right nephrectomy and thrombectmy

was performed on 27th May 20019(1398/03/06) with coupling of Pediatric surgeon and vascular Surgeon.

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Case3( Continue):

  • After nephrectomy and thrombectmy , the

patient condition is good .

  • Ascitis and pleural effusion are disapeared.
  • At present the treatment will be continued.
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Thanks for you Attention