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at a glance A general introduction to the project Facts and figures Acronym: CHIC Full title: Computational Horizons in Cancer: Developing Meta- and Hyper- Multiscale Models and Repositories for In Silico Oncology Duration: 48 months


  1. … at a glance … A general introduction to the project

  2. Facts and figures Acronym: CHIC Full title: Computational Horizons in Cancer: Developing Meta- and Hyper- Multiscale Models and Repositories for In Silico Oncology Duration: 48 months (start date: April 2013) Project funding: 10,582,000.00 € Programme: 7th Framework Programme of the European Commission – ICT – Large- scale Integrating Project (IP) Coordinator: Research Professor Georgios Stamatakos, Institute of Communication and Computer Systems (ICCS), National Technical University of Athens (NTUA), In Silico Oncology Group Website: www.chic-vph.eu 2014 CHIC at a glance 2

  3. The CHIC Consortium 2014 CHIC at a glance 3

  4. The CHIC Consortium 2014 CHIC at a glance 4

  5. The CHIC Objectives • Development of clinical trial driven tools, services and secure infrastructure for the creation of multiscale cancer hyper-models (integrative models). • The secure hypermodelling infrastructure consists primarily of a hypermodelling editor and a hypermodelling execution environment . • Development of an infrastructure for semantic metadata management along with tools and services for ontology based annotations . • Standardization of cancer model and data annotation allowing multiscale hypermodelling. • Development of hypermodel repository , a hypermodel-driven clinical data repository , a distributed metadata repository and an in silico trial repository for the storage of executed simulation scenarios, an image processing toolkit , a visualization toolkit and cloud and virtualization services . • Three concrete clinical trials/studies (nephroblastoma, glioblastoma and non-small cell lung cancer) 2014 CHIC at a glance 5

  6. The CHIC Objectives • Development of a number of integrative multiscale cancer models (hypermodels) and hypermodel oncosimulators and their clinical adaptation and partly validation. • An integrative platform dictated by the IT architecture of the project will provide access to all hypermodelling tools and services to be developed. • Legal and ethical aspects (legal and the IT aspects of data anonymization and pseudonymization, patient's consent) • Intellectual rights issues arising from the amalgamation of component models potentially developed by different modellers in order to construct integrative models. • Dissemination and exploitation (stakeholders: clinicians, fundamental science researchers, IT specialists and engineers, industry and patients). 2014 CHIC at a glance 6

  7. The CHIC Structure 2014 CHIC at a glance 7

  8. The CHIC Work Packages 2014 CHIC at a glance 8

  9. The VPH community 2014 CHIC at a glance 9

  10. Contact Scientific contact Administrative contact Research Professor Georgios Stamatakos Julia Petry Institute of Communication and Computer European Research and Systems (ICCS Project Office GmbH National Technical University of Athens (NTUA) Saarbrücken, Germany In-Silico Oncology Group * gestam@central.ntua.gr * j.petry@eurice.eu This project has received funding from the European Union Seventh Framework Programme for research, technological development and demonstration under grant agreement n° 600841. 2014 CHIC at a glance 10

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