Antibiotic Stewardship & Conservancy in Africa Sabiha Essack - - PowerPoint PPT Presentation

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Antibiotic Stewardship & Conservancy in Africa

Sabiha Essack

• B. Pharm., M. Pharm., PhD

South African Research Chair in Antibiotic Resistance & One Health School of Health Sciences, University of KwaZulu-Natal

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Overview

• Antimicrobial Resistance
• African Context
• Partners
• Aim & Objectives
• Study Design & Conceptual Framework
• Progress against Outcomes
• Envisaged Impact
• Successes
• Acknowledgements

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AMR: A Global Public Health Emergency

http://whqlibdoc.who.int/publications/2012/9789241503181_eng.pdf http://www.tufts.edu/med/apua/about_us/publications_21_3125925763.pdf

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AMR (2): The Consequences

www.jpiamr.eu/wp-content/uploads/2014/12/AMR-Review-Paper-Tackling-a-crisis-for-the-health-and-wealth-of-nations_1-2.pdf http://www3.weforum.org/docs/WEF_GlobalRisks_Report_2013.pdf

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AMR: WHO Response 2001-15

WHO efforts on an-microbial resistance

2014 2015 2001 2003 2011 2013 2012

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The African Context

http://apps.who.int/iris/bitstream/10665/112738/1/9789240692671_eng.pdf

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The African Context (2)

• The main cause of death in sub-Saharan Africa are

communicable diseases (respiratory tract infection, diarrhoea and HIV/AIDS).

• Antimicrobial resistance confounds the successful

management of infectious diseases.

• Capacities related to surveillance of antimicrobial use and

resistance, infection control, drug legislation and distribution, veterinary sciences, health economy etc. are

• ften limited in sub-Saharan Africa.

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Partners

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Aim

To develop human capital and research capacity in a global health priority. i.e., the

• ptimal management of infections in the

context of antimicrobial stewardship and conservation.

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Objectives

• Strengthen research, curriculum development and

pedagogical skills among academics, students and health professionals through design and implementation of online and research-based post-graduate training programmes (Masters & PhD)

• Advance the optimal management of infections and improve

key infection-related health statistics by conducting research to generate knowledge and evidence on the nature and extent of antimicrobial resistance with a view to designing context-specific interventions for its containment.

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Study Design & Conceptual Framework

3 Phases:

• 1. Situational Analysis
• 2. Curriculum

Development for On- Line Masters

• 3. Human Capital

Development

Antimicrobial stewardship

gender curriculum antimicrobial use and resistance socio- behavioral factors policy and health systems monitoring and evaluation

GAP: SO1 GAP: SO2&4 GAP: SO5 GAP: SO2&3 GAP: SO3&4

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Progress Against Outcomes :

Strengthened Higher Education Institutions

• New Postgraduate Programmes approved/
• ffered:

– ISCISA: Ministry of Education approved the research Masters and online M H Sc programmes for delivery in 2016 & 2017 respectively. – UNIMA: Intake into research-based M. Phil will occur in October 2016 and on the online M H Sc in 2017.

• E-teaching and learning platform commissioned

– Hardware purchased and commissioned

• Faculty & Staff Development

– Workshops on (1) e-teaching and (2) curriculum development for online programmes held.

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Progress Against Outcomes :

Strengthened Higher Education Institutions (2)

• Faculty development:

– ISCISA: 5/7 Masters & 5/5 PhD students are Faculty – UNIMA: 7/10 Masters and 1/2 PhD students are Faculty

• Technical staff development

– 2 IT personnel from each of ISCISA & UNIMA trained in (1) commissioning hardware, (2) operating systems & (3) Moodle

• Administrative Staff Development

– Finance Officer and Project Manager from ISCISA and Finance Office from UNIMA trained in financial management and reporting

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Progress Against Outcomes :

Strengthened Health Systems

• Reference Laboratories commissioned.
• Laboratory personnel trained in use of equipment
• Practical workshops on antibiotic susceptibility

testing held towards generating SoPs for surveillance.

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Progress Against Outcomes :

Enhanced Research Capacity/Competency

• Workshops on (1) proposal writing and (2)

statistical analysis held.

• Team supervision has enhanced the supervision

capacities of all supervisors.

• Cohort supervision introduced.

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Progress Against Outcomes : Human Capital Development

Human Capital ISCISA UNIMA TOTAL GRAND TOTAL F M F M F M Masters Students 6 1 4 6 10 7 17 PhD Students 2 3 2 4 3 7 Faculty PG Students 7 3 3 5 10 8 18 Shadow Teachers 9 3 9 3 18 21 IT Staff 2 2 4 4 Administrative Staff 2 1 2 1 3 Laboratory Staff 2 2 1 1 3 3 6

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Progress Against Outcomes : Knowledge Generation to Inform Policy & Practice

• Country situational analysis undertaken towards

National Action Plans on AMR.

• “Research Priority Setting” workshops held to

inform research topics & contribute to National Health Research Agenda.

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Progress Against Outcomes : Increased Participation & Stature of Women

27 71 59 68 60 73 29 41 32 40

UKZN UiT ISCISA UNIMA TOTAL Participation by Gender

Male Female

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Envisaged Impact

Direct Indirect

Facilitate progress towards achieving SDGs by:

• Creating a critical mass of Masters and PhD credentialed faculty &

healthcare professionals, particularly women, with the requisite biomedical, clinical, social sciences and/or policy-related knowledge and skills to improve the capacity of health systems to manage infections and contain antimicrobial resistance & advance stewardship. Aligned with the African Union’s programmes:

• Social Affairs: Health, Nutrition and Population
• HR, Science and Technology
• Women, Gender and Development

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Successes

• Unequivocal endorsement by Ministries of

Health and Education in both countries.

• Strong commitment & facilitation by University

leadership

• Recognition by WHO AFRO as a flagship project

with a view to replication in other African member states

• Contributing to the Global Action Plan on AMR

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Acknowledgements

We are grateful to:

• Professor Sundsfjord & UiT for convening

this symposium.

• NORAD for funding, freedom of choice in

research areas and a capacity strengthening and developmental ethos at all levels.