ADAPTABLE: Whats the right dose of aspirin if you have heart - - PowerPoint PPT Presentation

Adrian F. Hernandez, MD, MHS

ADAPTABLE: What’s the right dose of aspirin if you have heart disease?

Vice Dean for Clinical Research, Duke University @texhern September 19, 2019

2

Presenter Name

Disclosures

Rela latio ionship ip Company ny(ies es) Speakers Bureau Advisory Committee Board Membership NEST Consultancy AstraZeneca, Bayer, Boehringer Ingelheim, Boston Scientific, Merck, Novartis Review Panel Honorarium Ownership Interests [Note to presenter: Please use only this slide OR the next slide depending on your disclosure information.]

3

4

ADAPTABLE Study Design

5

5

http://adaptablepatient.com

6

Adapting to a Computable Phenotype

7

Testing out Best Recruitment Methods

8

The ADAPTORS

9

Engaging a Potential Participant

9

10

Health Care Systems Participating in ADAPTABLE

ClinicalTrials.gov: NCT02697916

11

Adaptable by the Numbers

• 657,215 identified as eligible
• 450,577 approached
• 32,087 Golden Tickets Entered
• 15,076 Participants Randomized

Across 40 sites in PCORnet Recruiting 5-10X faster

12

Learn More

• www.pcori.org
• info@pcori.org
• #PCORI2019
• adaptablepatient.com

13

Questions?

14

Thank You!

Adrian Hernandez

Vice Dean for Clinical Research, Duke University @texhern September 19, 2019