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Facilitated by the National Materials and Manufacturing Board, Division on Engineering and Physical Sciences A Quadr drennia ial Revie iew of the Natio ional l Nanotec echn hnology ology Init itia iativ ive The report t can be found


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SLIDE 1

A Quadr drennia ial Revie iew of the Natio ional l Nanotec echn hnology

  • logy Init

itia iativ ive

The report t can be found nd at: NAP.EDU DU/2 /25729

Nan anosci cience ence, , App pplic icat ation ions, , an and d Comme mmerci cial aliz izat ation ion

Tuesd sday, June 9, 2020 from 1-2:30pm 0pm ET 2020

Facilitated by the National Materials and Manufacturing Board, Division on Engineering and Physical Sciences

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SLIDE 2

Orig igin ins of the e NNI

2

In a January 2000 speech president Bill Clinton advocated the development of nanotechnology, at the California Institute of Technology

Image credit: AP

‘Some of our research goals may take twenty or more years to achieve, but that is precisely why there is an important role for the federal government.’

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SLIDE 3

3

President George W. Bush further increased funding for nanotechnology. On 3rd of December 2003 Bush signed into law the

21st Centur ury y Nanot

  • techno

chnolog

  • gy

y Research ch and Developme ment nt Act.

Public Law 108-153

Image credit: Brandi L. Schottel and Barbara Karn

Orig igin ins of the e NNI

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SLIDE 4

4

Today the NNI is a United States Government research and development initiative involving 20 agencies and departments working together toward the shared vision of developing - A futu ture e in which h th the abilit ility y to under derstand tand and d contr trol

  • l matt

tter r at t th the nanos noscale cale leads ds to a revolu

  • lutio

tion n in technology nology and d indus dustr try th that t bene enefit its s society ty.

The NN e NNI Toda day

https://www.nano.gov/about-nni

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SLIDE 5

5

The NNI brings together the expertise needed to advance this very broad and complex field — creating ting a frame mework k for shared d goals, , pri riorit ritie ies, s, and stra rategies ies that helps each participating Federa ral l agency y leverage ge the resources es of all partic ticipa ipating ting agencies cies. . With the support of the NNI, nanotechnology R&D is taking place in acade demic, mic, govern rnme ment, nt, and indust ustry y labora ratories ries across the United States.

The NN e NNI Struc ucture ture and C d Coordi dination ion

The NNI is coordinated by the Nanoscale Science, Engineering, and Technology (NSET)* - a subcommittee of the National Science and Technology Council's (NSTC) Committee on Technology, under the White House Office of Science and Technology Policy.

*Composed of representatives from the 20 Federal agencies and departments

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SLIDE 6

6

Pursuant to the 2003 21st Century Nanotechnology Research and Development Act The National Nanotechnology Coordination Office asked the National ional Academies demies of Scienc ences, es, En Engine neering, ering, and d Medicine icine to form an ad hoc review committee to conduct this quadrennial review of the National Nanotechnology Initiative (NNI)

202 020 0 Revie iew of the e NNI

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SLIDE 7

Statemen ement t of Task

This qua uadrennia rennial l NNI NI revie iew addre resse ssed d the e follo lowing ng task sks:

  • A. An

Analyze yze the e relati tive e positi tion

  • n of the

e Un United ed States es compared to other nations with respect to nanotechnology R&D, including trends and developments in nanotechnology science and engineering and the identification of any critical research areas where the United States should be the world leader to best achieve the goals of the Program

  • B. As

Assess ss the e cur urren ent t state e of nanoscience and nanotechnology resulting from the NNI as authorized in 2003, including the current impact of nanotechnology

  • n U.S. economic prosperity and national security. Based on this assessment,

consider nsider if and how w the e NNI NI shou

  • uld

ld continue

  • ntinue. If continuation is suggested, make

e recomm commen endat dations ions regar ardi ding ng new w or revis ised ed Program ram goals, s, new w resear search ch areas s and techn hnica cal l priorit rities ies, , partner tnersh ship ips, s, coor

  • rdi

dinati nation

  • n and mana

nagem gemen ent t mechanis chanisms, ms, or programs grams to be establ ablis ishe hed d to achie ieve e these ese goals. s.

7

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SLIDE 8

NNI NI Qua uadren renni nial al Revie iew w Comm mmitt ttee ee

LIESL FOLKS, University of Arizona, Chair HAYDN WADLEY, University of Virginia, Vice Chair NICHOLAS L. ABBOTT, NAE, Cornell University OLIVER BRAND, Georgia Institute of Technology HAROLD CRAIGHAED, NAE, Cornell University MARIE D’IORIO, University of Ottawa TRAVIS EARLES, Lockheed Martin Corporation GRAHAM R. FLEMING, NAS, University of California, Berkeley TERI W. ODOM, Northwestern University RICARDO RUIZ, Lawrence Berkeley National Laboratory JO ANNE SHATKIN, Vireo Advisors MARK TUOMINEN, University of Massachusetts, Amherst

Staff

ERIK SVEDBERG, Study Director JAMES LANCASTER, Director, NMMB and BPA NEERAJ P. GORKHALY, Associate Program Officer AMISHA JINANDRA, Research Associate BETH DOLAN, Financial Associate JOE PALMER, Program Coordinator

8

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SLIDE 9

Antti J. Makinen, CIV USN CNR James Alexander Liddle, NIST World Nieh, USDA Alan Rudie, USDA Samuel Brauer, Nanotech Plus, LLC Celia Merzbacher, SRI Thomas A. Treye, U.S. CPSC OHIR Peidong Yang, Berkeley Matthew Hull, Virginia Tech Chad Mirkin, Northwestern University Matt Laudon, TechConnect Orin Herskowitz, Columbia Technology Ventures Waguih Ishak, Corning and Emilie J. Siochi, NASA. Lisa Friedersdorf, NNCO Lloyd Whitman, NIST Mihail C. Roco, NSF Stephanie Morris, NIH Anil Patri, FDA Michael A. Meador, NASA Hongda Chen, USDA NIFA Khershed Cooper, NSF Paul Westerhoff, Arizona State University Yan Borodovsky, retired Hilary Godwin, University of Washington Nathan S. Lewis, California Inst. Technology Andre Nel, UCLA Peter Dröll, Germany The commi mittee e is gratefull lly y to the reviewers of the repor

  • rt

Muhammad Alam (Purdue University), Jennifer Dionne (Stanford University), Michael Ettenberg, NAE (Dolce Technologies), Michael Liehr, (SUNY Polytechnic Institute), Henke E. Riel, (IBM Research), Matthew Tirrell, NAS/NAE (University of Chicago) And also Martin A. Philbert, NAM (University of Michigan) for his oversight of the review.

Contribu ntributor

  • rs

s to the NNI I Qua uadrenni rennial al Revie iew

The committee thanks the following for their contributions to this study and participation in the committee’s meetings:

9

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SLIDE 10

Preface eface

  • Nanotechnology is highly-interdisciplinary and has made transfor
  • rmati

mative e societal tal imp mpact acts.

  • Nanotechnology significantly contributes to the US high-technology economy, the

nation’s security, to the health and to the prosperity of its citizens.

  • The US maintains a strong nanoscience and technology R&D program, but the global

bal arena is increa easi singl ngly compe mpeti titi tive.

  • Program

m coordi dina nati tion

  • n is now critical in the current hyper-competitive global era.
  • In China, particularly, we see a robust

st nationa

  • nal R&D strategy

egy that seeks to harvest the economic, medical, and national security benefits of the international nanotechnology R&D effort as quickly as possible.

  • Very large investments in state-of-the-art facilities and the allocation of

substantial resources for the training and attraction of top international talent, is clearly intended to result in China’s leadership in nanotechnology.

11

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SLIDE 11
  • A re

redesign sign of the NNI with the goal of achieving a U.S. re resurg rgen ence ce in nanot

  • techn

echnolog

  • logy

y is recommended.

  • The NNI should be restructured around these prioriti

ties es:

  • 1. Improve NNI alignment with the stated

ed natio ional nal priorities ties for R&D.

  • 2. Broaden NNI work to accel

elerat erate e techno nology

  • gy tra

ransf sfer er to relevant markets.

  • 3. Strengthen state-of-the-art enabling R&D infrastructure

astructure and expand domestic workfor

  • rce

ce education and training.

  • Engaging

ging and partne nering ng with the nanoscience and technology community broadly will be vitally important if the US is to fully reap the societal benefits of nanotechnology.

Summary mary

The highest est priority ty of this s report t is to provide de recomm mmenda ndati tions ns that t will restor

  • re

e the US to the glob

  • bal forefr

front

  • nt of nanot
  • techn

echnol

  • logy
  • gy-en

enab abled ed advan ances ces in electr ctroni nics cs, health th care, clean n energy gy, food d producti ction,

  • n, and clean

an water and air, and to contribut tribute e to the robust ust defen ense se of U. U.S. . nation

  • nal securit

urity interes rests. ts.

12

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SLIDE 12

Intr troduc

  • duction

tion

13

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SLIDE 13

The goals s of the e NNI I are:

  • 1. Advance a worl

rld-cla class ss nanote

  • techn

chnology logy R&D program gram.

  • 2. Foster the trans

nsfe fer r of new w technol chnolog

  • gies

ies into to produ ducts cts for commercial and public benefit.

  • 3. Develop and sustain educational resources, a skilled

led work rkforce force, and a dynami namic infras astru ruct cture re and toolset to advance nanotechnology, and

  • 4. Support respon

ponsib sible le devel velopme

  • pment

nt of nanotechnology

  • The NNI is widely viewe

wed d nationally

  • nally and global

bally ly as a highl hly y suc uccess essfu ful cross-disciplinary and interagency coordination effort — arguably the best modern example of such an effort in the US.

  • Impressive, tangible outcomes that have emerged from these coordination

efforts, including the recent cent forma rmati tion

  • n of the

e NQI.

Impa pacts cts of the e NNI to da date

14

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SLIDE 14
  • NNI is organized into Program

gram Comp mponent

  • nent Areas

as and Nanotechnology echnology Signat gnature ure Initiati tiatives es to promote interagency eragency coor

  • rdination

nation in areas of nati tional

  • nal rele

levanc ance.

  • This “light coordination” approach has resulted in uneven

en investments estments.

  • Poorly funded: technology transfer and workforce development
  • Well funded: fundamental research, infrastructure, health, and public safety.
  • A lack

ck of data ta collec llection

  • n / avai

vailabi lability makes it difficult to determine impacts.

  • We observe signi

nificant cant iner ertia a to chang ange e in prior

  • rities

es hampering timely alignment with national priorities.

  • In the past, when the global arena was paced by the work of the United States, this

approach to NNI coordination was more appropriate than it is today.

Orga ganiz izati tion

  • n of NNI ef

effor

  • rt

t via ia PC PCAs s and N d NSIs

Given en intense nse compe mpeti titio tion n and increa easi sing ng risk of technolog nologica ical surprise, se, the review w commi mitt ttee ee is concerned cerned that t the organiz izing ng princi cipl ples es and budg dgeta etary arrangemen ements ts to execu cute e an agile e program m are no longe ger adequat ate. e.

16

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SLIDE 15

The U e U.S. Nanotec echn hnology

  • logy R&D

&D Ecosys

  • system

em

  • There are many notable NNI successes

cesses, in electronics, healthcare, environmental nanosensors, the development of world-class ass fa faci cilit ities es, and establishment of the US as a glob

  • bal

al leader er in EHS efforts.

  • Comparison of U.S. and international efforts reveals key compet

petit itiv ive e weakne ness sses es for the U.S. efforts.

  • While support of basic nanoscience research must continue, the opportunity now exists

for the United States to fully realize e the socie ieta tal bene nefit its s of nanosc

  • scien

ence ce via commercialization of responsible nanoproducts. There e exists sts an urgent t need to bett etter er integr grat ate e nanosc

  • scien

ence, ce, infrastructure astructure development elopment, and workfor

  • rce

ce developmen

  • pment

t into

  • an ecosys

system em that t suppor

  • rts

ts the goal

  • f responsib

nsible e commer mercia cializ izat ation

  • n of nanot
  • techno

echnology

  • gy for the bene

nefit it of the US.

17

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SLIDE 16

Current ent Per erspe pecti ctive

  • The SARS-COV2 pandemic has shown the value and critical importance of advanced

science and technology research and infrastructure to society.

  • The rapid response in sensors, testing and potential vaccines has been facilitated by

nanotechnologies.

  • 20 years of the NNI has built significant resources and learning, in particular about

interdisciplinary research and technology development.

  • It is time to pivot the NNI to align with current US Strategic R&D Priorities.

18

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SLIDE 17

The Ch e Changi ging g Global bal Envir ironmen

  • nment

19

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SLIDE 18

A Global bal Per erspe pecti ctive

  • At the launch of the NNI, 20 years ago, governmen

ernment t investmen estment t into nanotech and R&D was on par between the United States, Western Europe, and Japan, and the United States had a strong ng lead in the number mber of patent nts in nanotechnology.

  • Susta

taine ned d investm estment nts have been made by other developed nations and the EU, and accel elera erated ed investmen estment t is seen in developing nations, especially China.

  • Today, the US is but

t one of several al nation ions s where nanoscience discoveries and technology applications are making important contributions to the economy and to the health of their citizens.

  • It is unrealistic to expect or to advocate that the United States should lead in every

area of nanoscience and technology.

  • There is a need to identi

tify fy the most t critica ical topics ics in which h the Un United ed States es should uld aim to lead the world.

20

So how w has the e NNI I evol

  • lved

ed com

  • mpared

ared to the e nano no-pr programs

  • grams of ot
  • ther

her nations

  • ns?
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SLIDE 19

Source: Extracted from the nanotechnology database recently published in Z. Wang, A.L. Porter, S. Kwon, J. Youtie, P.

Shapira, S.F. Carley, and X. Liu, 2019, “Updating a search strategy to track emerging nanotechnologies”, Journal of Nanoparticle Research 21(9):199. The committee thanks the authors for permitting a customized search of their database.

21

Rapid Global Shifts in Origins of “Nano-related” Publications

China US

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SLIDE 20

10,000 20,000 30,000 40,000 50,000 60,000 70,000 80,000

1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

Number of publications

23

Nanotechnology publications in the WoS: 1990 - 2018

“Title-abstract” search for nanotechnology by keywords for five regions

2000-2018 Average worldwide annual growth rate ~15%

U.S. ~ 20% China ~ 43% in 2018 U.S.# ~ 30% China ~ 9% in 2000 U.S. ~ 23% China ~ 24% in 2010

U.S. contribution fell from ~30% in 2005 to ~20% in 2018 (about -0.7% per year)

U.S. ~ 29% China ~ 16% in 2005

MC Roco and HN Chen, Dec 9 2019 Japan USA Korea China EU 27

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SLIDE 21

Total Asia EU-28 and EFTA North America Number % Number % Number % ICT 809,820 419,031 51.7 255,411 31.5 166,130 20.5 Manufacturing 286,447 158,468 55.3 84,476 29.5 51,245 17.9 Health 266,741 112,740 42.3 87,452 32.8 71,418 26.8 Energy 197,539 116,294 58.9 51,263 26.0 41,353 20.9 Photonics 112,378 56,012 49.8 36,215 32.2 29,711 26.4 Environment 66,100 28,683 43.4 21,595 32.7 14,915 22.6 Transport 22,803 8,767 38.4 9,090 39.9 6,353 27.9 Construction 21,648 7,124 32.9 8,651 40.0 4,042 18.7 1,783,476 907,119 50.9 554,153 31.1 385,167 21.6 SOURCE: Data from European Commission, 2018, NanoData Landscape Compilation Update Report 2017, doi: 10.2777/031727, at https://op.europa.eu/en/publication-detail/-/publication/69470216-f1f6-11e8-9982- 01aa75ed71a1/language-en/format-PDF/source-81483247, accessed 11/04/2019.

24

Nanot notechnol chnology

  • gy Pub

ublica cati tions

  • ns by Ap

Applicati tion

  • n Field

ld and Region ion (2000 00-16) 6)

Total Asia EU-28 and EFTA North America Number % Number % Number % ICT 809,820 419,031 51.7 255,411 31.5 166,130 20.5 Manufacturing 286,447 158,468 55.3 84,476 29.5 51,245 17.9 Health 266,741 112,740 42.3 87,452 32.8 71,418 26.8 Energy 197,539 116,294 58.9 51,263 26.0 41,353 20.9 Photonics 112,378 56,012 49.8 36,215 32.2 29,711 26.4 Environment 66,100 28,683 43.4 21,595 32.7 14,915 22.6 Transport 22,803 8,767 38.4 9,090 39.9 6,353 27.9 Construction 21,648 7,124 32.9 8,651 40.0 4,042 18.7 1,783,476 907,119 50.9 554,153 31.1 385,167 21.6

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SLIDE 22

Global nanotechnology patents recorded in the WIPO data base, by lead author location. SOURCE: Reprinted by permission from Springer Nature: H. Zhu, S. Jiang, H. Chen, and M.C. Roco, 2017.

25

Rapid d Global bal Shif ifts ts in Origin in of Pat Patents nts

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SLIDE 23

Output put of high-tec echn hnology

  • logy manuf

ufac actur turin ing g industr ustries ies for select lected ed regions, ions, countr tries, ies, or economies

  • mies (2003 – 2016)

SOURCE: IHS Global Insight, World Industry Service database (2017) &National Science Board, 2018, Science and Engineering Indicators.

26

China na US US EU EU

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SLIDE 24

Bachel helor

  • rs

s Degre ree Degree ree awards ds in S and E f E fields lds by coun untr try y or econ

  • nomy

China na US US EU 6

SOURCE: National Science Board, Science & Engineering Indicators 2020, https://ncses.nsf.gov/indicators, Figs 3 and 4.

27

PhD Degrees rees

China na US US EU 6 India ia Taiwan an Japan S Kore rea

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SLIDE 25

Conc ncluding ding Rema marks s on the e Global bal Nanot notech echnol nology

  • gy R&D Ec

Ecosy syst stem em

The US remains ns a c comp mpeti etitor

  • r in nanotechnology, but no longer

r the unambiguous uous leader. Developed and emerging economies have implemented mechanisms that raise the scale and productivity of their programs:

  • Prolong

nged ed and focused used suppo pport of the most innovative basic c scienc ence resear arch h and techno hnology y developm

  • pment.

ent.

  • Agile, and highl

hly y effecti ctive, , coordi dina nati tion

  • n among national and regional agencies to maximize the

impacts on societal problems in recognized areas of strategic importance.

  • Integ

egrat rated d R&D efforts ts address essing societal etal challenges nges that are highly interdisciplinary.

  • Novel, highly effective, coordina

dinati tion

  • n of resear

earch ch in disp sparat rate fields ds has contributed significantly to the rapid rise of new centers of leadersh ship p outside the United States.

  • Promoti
  • tion

n of government nment-ind ndustr ustry partne tnerships hips, to create and nurture national nanotechnology ecosystems, and to speed d the commerci cializa zati tion

  • n of promising R&D.
  • Creati

tion n and maint ntenanc enance e of share ared d state-of

  • f-the

the-art t nanot

  • tech

chno nology gy inf nfra rastru ruct ctur ure e that supports fundamental and applied science, commercialization of nanotechnology products, and development of nanotechnology-enabled systems and applications.

  • National

nal educati tiona nal and traini ning ng polici cies es to promote the rapid growth of a highly trained and nanotechnology-skilled workforce.

28

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SLIDE 26

Key y findings dings an and recommenda commendations tions

29

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SLIDE 27

1 1 – STRATEGI TEGIC C AL ALIGNMENT IGNMENT WITH H NATIONAL TIONAL PRIORITIES RITIES Findin nding 1. 1.1: 1: The activities of the National Nanotechnology Initiative (NNI) and its current signature initiatives, while addressing relevant societal challenges, are not explicitly aligned with the current research and development (R&D) priorities established by the federal government. Findin nding 1. 1.2: 2: The National Quantum Initiative (NQI) is, in large part, an important outgrowth

  • f the National Nanotechnology Initiative (NNI), but the degree of coordination

and collaboration between these national high-priority efforts is not yet clear. Findin nding 1. 1.3: 3: The goals of the Bioeconomy Initiative overlap with those of the National Nanotechnology Initiative (NNI) toward advanced manufacturing, creating an

  • pportunity to leverage nanomanufacturing infrastructure and the coordinating

relationships of the NNI in service of advancing the Bioeconomy Initiative.

30

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SLIDE 28

Images Courtesy of Berkeley Lights

An exam ample ple of how nanotech chnolog nology y contribu ributes es to national ional strat rategi egic R&D priorities iorities – the Bioe

  • eco

conom nomy y and COVID ID-19 Respo sponse nse

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SLIDE 29

Findin ding g 1. 1.4: U.S. competitiveness in nanotechnology is slipping in some areas, putting U.S. economic prosperity and national security at risk. Findin ding g 1. 1.5: The United States is not investing significant resources in nanotechnology in ways that are as focused and strategic as in

  • ther nations.

Findin ding g 1. 1.6: U.S. nanotechnology stakeholders report considerable challenges along the lab-to-market path for nanotechnology-based products.

32

1 1 – STRATEGI TEGIC C AL ALIGNMENT IGNMENT WITH H NATIONAL TIONAL PRIORITIES RITIES

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SLIDE 30

33

Key y Recommenda commendation tion 1: The Nanoscale Science, Engineering, and Technology (NSET) Subcommittee and the National Nanotechnology Initiative (NNI) agencies should align ign the e effor

  • rts

ts of the NNI to deliver responsible and sustainable nanotechnology-based solutions that address the e federal deral resea earch ch and d de devel elop

  • pment

ment (R&D) D) priorities

  • rities, which currently

include security, artificial intelligence, quantum information sciences, manufacturing, bio-based materials, water, climate change, space travel, exploration, inhabitation, energy, medical innovations, and food and agriculture.

1 1 – STRATEGI TEGIC C AL ALIGNMENT IGNMENT WITH H NATIONAL TIONAL PRIORITIES RITIES

slide-31
SLIDE 31

Implemen lementation tation Recomm

  • mmend

endati ation

  • n 1a:

Convene multiagency coordination efforts to align gn the e Natio ional al Nanotech chnolog nology y Initi tiativ ative e (NNI) I) priorities

  • rities with

h federal ral resear search h and develo lopm pment nt (R&D) D) priorities

  • rities.

Implemen lementation tation Recomm

  • mmend

endati ation

  • n 1b:

Facilitat litate e ongoing ing close e partner tnership ship and collab abor

  • rati

ation

  • n bet

etween een the National ional Nanotec echnolo hnology gy Init itiat iativ ive (NNI) NI) and Nati tional nal Quantum ntum Initiativ tiative e (NQI) QI) to minimize duplication of effort, maximize the utilization of existing infrastructure, and allow for cross-pollination

  • f ideas across both initiatives.

34

1 1 – STRATEGI TEGIC C AL ALIGNMENT IGNMENT WITH H NATIONAL TIONAL PRIORITIES RITIES

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SLIDE 32

Implemen lementation tation Recomm

  • mmend

endati ation

  • n 1c:

Through the National Nanotechnology Coordination Office (NNCO) and interagency efforts, align gn the National ional Nanotec echnology hnology Initiativ tiative e (NNI) I) and the Bioec econom

  • nomy

y Initi tiativ ative to leverage research and development (R&D) and coordination efforts on nanotechnology to strengthen the bioeconomy, including biotechnology, bio-based products, and sustainable bioproduction, including molecular assembly. Implemen lementation tation Recomm

  • mmend

endati ation

  • n 1d:

To address the need for closer coordination and agile refocus on strategic opportunities, the NNCO O should ld be adequat ately ely resour

  • urced

ed to fully ly inter eract ct with th NNI agencies ies and hold those agencies accountable to the new plan.

35

1 1 – STRATEGI TEGIC C AL ALIGNMENT IGNMENT WITH H NATIONAL TIONAL PRIORITIES RITIES

slide-33
SLIDE 33

2 2 – COMMER ERCIA CIALIZ LIZATION TION OF NAN ANOTE TECHNOL CHNOLOG OGY

36

slide-34
SLIDE 34

A FEW KEY FINDINGS INGS

  • Other countries and regions have evolved their central nanotechnology research and

development (R&D) efforts to incorporate a strong

  • ng emp

mphasis hasis on comm mmer erci cial al trans nslat lation

  • n,

yielding lab-to-market pathways that are accelerated relative to those in the United States. (Examples: EU Horizon 2020, Japan, China)

  • Supporting knowledge transl

nslation ation and technology chnology trans nsfer er has not been a sufficiently major focus of the National Nanotechnology Initiative (NNI) to date.

  • Data

ta on the competiti titive e status atus of the United States with regard to nanotechnology implementation and commercialization is unavailable through the National Nanotechnology Initiative (NNI) public-facing digital portals.

  • Pilo

lot and test st-bed bed fa faci ciliti lities es are a key part of lab-to-market and return-on-investment

  • activities. The United States has not maintained a competitive position with this type of

facility.

37

2 2 – COMMER ERCIA CIALIZ LIZATION TION OF NAN ANOTE TECHNOL CHNOLOG OGY

slide-35
SLIDE 35

38

Key Recommend

  • mmendation

ation 2: The Nanoscale Science, Engineering, and Technology (NSET) Subcommittee and the National Nanotechnology Coordination Office (NNCO) should stren rengthe gthen n and expa pand nd the lab-to to-mark market t inn nnovation ation ecosyst ystem em in support of the transfer of nanotechnologies from bench research to products, to ensure U.S. competitiveness.

2 2 – COMMER ERCIA CIALIZ LIZATION TION OF NAN ANOTE TECHNOL CHNOLOG OGY

slide-36
SLIDE 36

KEY IMPLEMENT ENTATION ON RECOMM MMEN ENDATIO IONS NS

  • Implement effective coordination among the various national or regionally supported

funding agencies to maximize mize the impact mpacts of funda ndamental ental research ch to advance applications and solutions to societal problems in recogni nized ed areas s of strat rategic gic impo mportan tance.

  • Develop a servi

vice model strat rategy y to suppo pport t commerci cializa zati tion

  • n activiti

vities es so as to ensure that (1) nanoproducts are made in the United States whenever possible, (2) relevant skills and expertise are developed locally, (3) barriers to commercialization are identified quickly, and (4) the national return on investment (ROI) is maximized.

  • Create appropriate data collecti

tion n met ethods ds and a data reposit sitor

  • ry

y to allow routine assessment of (1) the global status of nanotechnology, (2) new and emerging trends, and (3) the status and return on investment (ROI) of the National Nanotechnology Initiative (NNI) to be readily

  • assessed. Ideally the data collection process should not become a significant burden on the

researchers.

  • Expand efforts to build a national community of National Nanotechnology Initiative (NNI)

participants, and then leverage this community to improve access to national facilities, increase

  • pportunities for collaboration, create public-private partnerships, and generat

ate pathways ys for commerci cializati ation n of products ducts to global markets.

39

2 2 – COMMER ERCIA CIALIZ LIZATION TION OF NAN ANOTE TECHNOL CHNOLOG OGY

slide-37
SLIDE 37

KEY IMPLEMENT ENTATION ON RECOMM MMEN ENDATIO IONS NS (conti tinue nued) d)

  • Create a not
  • t-for
  • r-pr

prof

  • fit

t organi nizati ation n whose mandate is to connect National Nanotechnology Initiative (NNI) participants, industry, and academia through membership and provision of services such as ecosystem studies, national and international conferences, regional workshops, and turnkey missions for stakeholders to international trade shows abroad.

  • Assess the value of establishing a Nano-Manuf

anufac actu turing ring Insti titut ute e that would offer tools to and share expertise with small and medium-size enterprises (SMEs) to accelerate product development.

  • Expand international collaborations on respo

sponsibl nsible developm

  • pment

ent and manufacturi acturing ng, with the European Union in particular, and other countries as appropriate, to ensure transparent global standards emerge to the benefit of consumers and U.S. industry.

  • Leverage the recent

t Lab-to to-Market et Ret eturn rn-on

  • n-In

Investm estment nt (ROI) Initi tiati tive e to accelerate nanotechnology commercialization.

  • Enhance the trainin

aining of comp mpetent nt nanot

  • techno

chnology gy prof

  • fessio

essiona nals s in entre repr prene neursh urship, p, techno hnology y transf nsfer, , and commerci cializa zati tion

  • n are essential to lab-to-market return on investment.

40

2 2 – COMMER ERCIA CIALIZ LIZATION TION OF NAN ANOTE TECHNOL CHNOLOG OGY

slide-38
SLIDE 38

41

3 3 – NAN ANOTEC TECHN HNOL OLOG OGY INFRA FRASTR TRUCTURE UCTURE

slide-39
SLIDE 39

Finding nding 3.1: : Other countries have followed U.S. lead and are investing heavily in nanotechnology infrastructure. Finding nding 3.2: U.S. nanotechnology infrastructure is aging. Finding nding 3.3: Easy-to-access infrastructure is key enabler for researchers and start-ups. Finding nding 3.4: State-of-the-art infrastructure helps attract talent.

42

Nanoscale Science Research Centers www.nnci.net nsrcportal.sandia.gov www.nist.gov/cnst ncl.cancer.gov 3 3 – NAN ANOTEC TECHN HNOL OLOG OGY INFRA FRASTR TRUCTURE UCTURE

slide-40
SLIDE 40

Findi nding ng 3.1: : Other countries have followed the U.S. lead and are investing heavily in nanotechnology infrastructure. Finding nding 3.2: U.S. nanotechnology infrastructure is aging. Finding nding 3.3: Easy-to-access infrastructure is key enabler for researchers and start-ups. Finding nding 3.4: State-of-the-art infrastructure helps attract talent.

43

www.nanopolis.cn/en/ China Nano Valley https://www.nanonet.go.jp/ntj

3 3 – NAN ANOTEC TECHN HNOL OLOG OGY INFRA FRASTR TRUCTURE UCTURE

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SLIDE 41

Finding nding 3.5: U.S. nanotechnology infrastructure is lacking scale-up capabilities. Finding nding 3.6: Non-U.S. micro/nanotechnology centers attract U.S. companies because

  • f technology transfer capabilities.

Findi nding ng 3.7: : Need to redesign and streamline resources for inventors to facilitate commercialization of Nanotechnology.

44

www.imec-int.com Belgium France https://www.minatec.org/

3 3 – NAN ANOTEC TECHN HNOL OLOG OGY INFRA FRASTR TRUCTURE UCTURE

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SLIDE 42

45

New investments by the National Nanotechnology Initiative (NNI) agencies are required to strengt rengthen hen and rene new the U.S.

  • S. net

etwor

  • rk

k

  • f fabric

ricati ation

  • n and charact

acteriz erizati ation

  • n facilit

lities es to retain international leadership. These investments should make readily available new tools, expertise, techniques, and processes to support fundamental research in existing and emerging areas, as well as prototyping and pilot/scale-up capabilities.

3 3 – NAN ANOTEC TECHN HNOL OLOG OGY INFRA FRASTR TRUCTURE UCTURE

Key y Reco comm mmen enda dation tion 3:

slide-43
SLIDE 43

3 3 – NAN ANOTEC TECHN HNOL OLOG OGY INFRA FRASTR TRUCTURE UCTURE

Imp mplem ementa entati tion

  • n Recomme

mendati ndation

  • n 3a:

The National Nanotechnology Initiative (NNI) agencies should solici cit and promo

  • mote inno

nova vati tive e approac aches hes to transf nsform rm models s of access s to, and moderni rniza zati tion n of, the nanot

  • techno

chnology gy infr frast structure ructure to ensure U.S. leadership in lab-to-market outcomes. A whole-of-government approach is required to develop

  • p more thoughtf

ughtful ul, , strat rategic, gic, and effecti ctive e approa

  • aches

hes to accelera rate e techno hnology y transf nsfer

  • er. Effective collection of performance metrics is also needed. A

mechanism for moving this activity forward is to appoint a responsible person from, for example, the Department of Commerce.

46

slide-44
SLIDE 44

3 3 – NAN ANOTEC TECHN HNOL OLOG OGY INFRA FRASTR TRUCTURE UCTURE

Imp mplem ementa entati tion

  • n Recomme

mendati ndation

  • n 3b:

National Nanotechnology Initiative (NNI) agencies/organizations should develop p progra grams ms that t fund nd replace cement ent of aging g infrastru frastructu ture re (tools) s) in addition to programs for new, state-of-the-art infrastructure.

47

slide-45
SLIDE 45

4 4 – WOR WORKF KFOR ORCE CE DEV EVEL ELOPME OPMENT NT: : GLOBAL BAL VIEW EW ON COMPETI ETITI TIVENE VENESS SS

48

slide-46
SLIDE 46

Finding nding 4.1: The United States is losing global comp mpeti etiti tivenes eness in recruiting international graduate students and in training science, technology, engineering, and mathematics (STEM) students at all levels. Findi nding ng 4.2: The United States lacks an overarching strategy for gradua uate stude udent nt recruitment and development to support nanotechnology advancement.

49

2020 Nationa ional l Science ience Board

4 4 – WOR WORKF KFOR ORCE CE DEV EVEL ELOPME OPMENT NT: : GLOBAL BAL VIEW EW ON COMPETI ETITI TIVENE VENESS SS

slide-47
SLIDE 47

50

Key Recommend

  • mmendation

ation 4: Nanoscience-supporting agencies should significantly increase ease efforts ts to attr tract ct and train ain the best t stud uden ents ts to studies in relevant nanoscience / nanotechnology science, technology, engineering, and mathematics (STEM) disciplines to ensure a diverse, wo world ld-class lass workforce to support our national interests and security, including via pub ublic ic-priv privat ate e partn tner erships ips that support student fellowships.

4 4 – WOR WORKF KFOR ORCE CE DEV EVEL ELOPME OPMENT NT: : GLOBAL BAL VIEW EW ON COMPETI ETITI TIVENE VENESS SS

slide-48
SLIDE 48

Imp mplem ementa entati tion

  • n Recomme

mendati ndation

  • n 4a: NNI agencies, such as the National Science Foundation,

should seed the creation of undergraduate certificate programs in entrepre repreneu neurship hip in partnership with universities. Implemen ementa tati tion

  • n Recommenda

ndati tion

  • n 4b: The NNI agencies should increase and sustain the number
  • f Research Experiences for Undergraduates (REU) programs focused on nanoscie

scienc nce e and nanot

  • tec

echnol hnology gy. Imp mplem ementa entati tion

  • n Recomme

mendati ndation

  • n 4c: The NNI should create targeted internsh

ernship programs between nanotechnology companies and universities for undergraduate and graduate students.

51

4 4 – WOR WORKF KFOR ORCE CE DEV EVEL ELOPME OPMENT NT: : GLOBAL BAL VIEW EW ON COMPETI ETITI TIVENE VENESS SS

slide-49
SLIDE 49

Imp mplem ementa entati tion

  • n Recomme

mendati ndation

  • n 4d: NNI agencies should foster models that create teams of

nanotechnology graduate students, business ss scho hool stude tudents nts, and private sector stakeholders to advance inter erdis disci cipli plinary training in support of accelerated U.S. lab-to to-market et outcomes. Imp mplem ementa entati tion

  • n Recomme

mendati ndation

  • n 4e: The NNI should expand the diversity of STEM students by

gender, age, and ethnicity to greatly increase the nanotechnology workforce.

52

2020 Nationa ional l Science ience Board

4 4 – WOR WORKF KFOR ORCE CE DEV EVEL ELOPME OPMENT NT: : GLOBAL BAL VIEW EW ON COMPETI ETITI TIVENE VENESS SS

slide-50
SLIDE 50

5 5 – STRUCT UCTUR URE AN AND MAN ANAGEMENT GEMENT

53

slide-51
SLIDE 51

54

Key Recommen

  • mmendation

ation 5: The Nation ional al Nanotec echn hnology

  • logy Initi

tiativ ative e (NNI) I), through the Nanoscale Science, Engineering, and Technology (NSET) Subcommittee and the National Nanotechnology Coordination Office (NNCO), should uld continue inue to perform rm its s impor

  • rtant

tant coordinati inating ng role.

  • e. The NNCO should be adequat

uately ely resour sourced ed and appropria

  • priately

ely staffed ed to deliver an agile and globally competitive nanotechnology program. The work of the NNCO should also be augmented through expan panded ded collab abor

  • rati

ations

  • ns with

not-for-profit organizations and by establishing new public ic- privat ate e partner tnership ships. s.

5 5 – STRUCT UCTUR URE AN AND MAN ANAGEMENT GEMENT

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SLIDE 52

Imp mplem ementa entati tion

  • n Recomme

mendati ndation

  • n 5a: The National Nanotechnology Initiative (NNI) should signal to

all stakeholders that it is refocusing its efforts through a renaming or rebranding that captures the revised priorities recommended in this report. Implemen ementa tati tion

  • n Recommenda

ndati tion

  • n 5b: The Office of Science and Technology Policy (OSTP) should

evaluate the current budget level and funding mechanism with consideration to the expanded role

  • f the National Nanotechnology Coordination Office (NNCO) and provide specific guidance through

the Office of Management and Budget (OMB) to modify the level of flow through funding from participating agencies to ensure that the NNCO has the resources necessary to execute its responsibilities on behalf of the Nanoscale Science and Technology (NSET) Subcommittee. Imp mplem ementa entati tion

  • n Recomme

mendati ndation

  • n 5c: Nanoscale Science and Technology (NSET) and the National

Nanotechnology Coordination Office (NNCO) should actively leverage the Nanotechnology Signature Initiative (NSI) mechanism to focus and coordinate agency work and funding on activities such as technology transfer or training. Implemen ementa tati tion

  • n Recommenda

ndati tion

  • n 5d: Nanoscale Science and Technology (NSET) should coordinate

with grants.gov (or other federal research and development reporting avenues) to develop mechanisms to collect and present accurate, current performance data on the outcome of the National Nanotechnology Initiative (NNI) research and make clear to all, including to the researchers involved, what research is part of the NNI.

55

5 5 – STRUCT UCTUR URE AN AND MAN ANAGEMENT GEMENT

slide-53
SLIDE 53

Conclu

  • nclusions

sions

56

slide-54
SLIDE 54

The report Recommendations identifies these three priorities for shaping the future of the NNI: Priority ty 1.

  • 1. The NNI should improve alignment

nment with th the e stated ed nation

  • nal

al priori

  • rities

ties for R&D and focus us on strat ateg egic ically ally select cted ed environmental and other societal challenges. Priority ty 2. The NNI should partner ner broad roadly ly to improve the effic iciency ency of transla latio tion of nanoscience/nanotechnology research and development into economic, environmental, security, health, etc., (i.e. societal) benefits. Priority ty 3. The NNI should expand the nation’s nanotechnology ecosystem via increased recru ruitment itment and train ining ng of future scientists and engineers, with an intentional focus on accelerated technology translation, and with robust investments in next-generat generation

  • n infras

rastruc tructu ture re to support both basic science and commercialization.

A V A VISION SION FOR THE E FUTUR URE OF THE E NNI

57

slide-55
SLIDE 55

Thanks hanks for li listening! ening!

This s repor

  • rt

t has also

  • been brief

efed ed to NNCO, O, OSTP TP, , the NNI agencies, cies, and the Hill ll

We now w mo move e to Q& Q&A ple lease ase ty type pe in an any questions stions The he repor port t ca can be be found und at at: NA NAP.E .EDU/25 DU/2572 729

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