SLIDE 14 7/2/2020 14
Association between Maternal Gestational Weight Gain (GWG) and Child Weight Status
GWG Unadjusted
- Adj. for case status
- Adj. for case status
& demographic covariates
& maternal covariates
status, demographic & maternal covariates
status, demographic, maternal, & birth covariates OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P < IOM vs. > IOM 0.77 (0.56, 1.05) .095 0.75 (0.55, 1.03) .075 0.66 (0.47, 0.92) .016 0.78 (0.57, 1.07) .118 0.69 (0.49, 0.96) .029 0.77 (0.54, 1.09) .144 < IOM vs. = IOM 1.15 (0.83, 1.60) .393 1.11 (0.80, 1.55) .522 0.96 (0.67, 1.36) .799 1.14 (0.82, 1.58) .452 0.98 (0.69, 1.40) .928 1.01 (0.70, 1.46) .958 > IOM vs. = IOM 1.51 (1.19, 1.90) .001 1.48 (1.17, 1.87) .001 1.45 (1.14, 1.84) .003 1.46 (1.15, 1.85) .002 1.43 (1.13, 1.83) .004 1.32 (1.02, 1.69) .033
When controlling for case status, mothers who exceeded the GWG recommendations were 1.5 times more likely to have a child with obesity.
Kral et al., Autism, 2019
Frequency of Rapid Weight Gain Across Groups
ASD DD POP 10 20 30 40 50
44% 36% 33% P = 0.004
Rapid Weight Gain (% yes) Change in weight-for-age z-scores from birth to 6 months > 0.67 SD
Kral et al., Autism, 2019
Association between Rapid Weight Gain and Child Weight Status
Rapid weight gain Unadjusted
demographic covariates
covariates
demographic & maternal covariates
demographic, maternal, birth covariates OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P ASD: Yes vs. no 2.56 (1.60, 4.08) <0.001 2.60 (1.58, 4.27) <0.001 2.54 (1.58, 4.09) <0.001 2.65 (1.60, 4.41) <0.001 3.47 (1.85, 6.51) <0.001 DD: Yes vs. no 1.24 (0.83, 1.85) 0.302 1.30 (0.84, 2.00) 0.232 1.25 (0.83, 1.88) 0.286 1.32 (0.85, 2.05) 0.209 1.53 (0.92, 2.55) 0.098 POP: Yes vs. no 1.38 (0.88, 2.17) 0.158 1.44 (0.88, 2.35) 0.146 1.24 (0.78, 1.98) 0.363 1.26 (0.76, 2.09) 0.376 2.85 (1.44, 5.64) 0.003
Children w/ASD and rapid weight gain had 3.5 times greater odds of developing
- besity after controlling for all covariates.
Kral et al., Autism, 2019
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