WELCOME SESSION for New Students and Research Trainees - - PowerPoint PPT Presentation

welcome session for new students and research trainees
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WELCOME SESSION for New Students and Research Trainees - - PowerPoint PPT Presentation

WELCOME SESSION for New Students and Research Trainees INFORMATION SESSION January 26, 2018 1:30 p.m. to 4:00 p.m. YOURLOGO TABLE OF CONTENTS WELCOME MESSAGE GROUP PHOTO STUDENT AFFAIRS COMMITTEE STUDENT COMMITTEE


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YOURLOGO

WELCOME SESSION for New Students and Research Trainees

INFORMATION SESSION

January 26, 2018 1:30 p.m. to 4:00 p.m.

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TABLE OF CONTENTS

 WELCOME MESSAGE  GROUP PHOTO  STUDENT AFFAIRS COMMITTEE  STUDENT COMMITTEE  DEPARTMENT OF HUMAN RESOURCES  SHARED SERVICES/CORE FACILITIES  ANIMAL FACILITY AND THE CIPA  SAFETY AND BIOHAZARDS (legitimate absence)  CHUM LIBRARY  RESEARCH ETHICS BOARD  CRCHUM NEWS AND IMPACT AND MAJOR EVENTS  TRANSFERRING RESEARCH RESULTS  MITACS  TRICKS AND TIPS FOR SUCCESSFUL GRANT APPLICATIONS

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The CRCHUM A major hospital research centre in Quebec and in Canada

Approximately 2,000 people More than 400 researchers (130 regular researchers) More than 500 graduate students and postdoctoral fellows, and more than 200 research trainees More than 850 professionals An average of ~900 publications per year (regular researchers) 48,000m2 of new facilities at the cutting edge

  • f technology

A dozen state‐of‐the‐art technological core facilities A highly stimulating scientific life

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OUR VALUES

Excellence Respect Pride Integrity Commitment

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Group Photo

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ASSOCIATE SCIENTIFIC MANAGEMENT TEAM – STUDENT AFFAIRS

Pierrette Gaudreau, PhD Associate Scientific Director – Student Affairs President of the Student Affairs Committee pierrette.gaudreau@umontreal.ca Joanne Auclair Administrative Agent – Student Affairs joanne.auclair.chum@ssss.gouv.qc.ca

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RESEARCHER MEMBERS OF THE STUDENT AFFAIRS COMMITTEE

  • Dr. Pierrette Gaudreau

President Cardiometabolic Research Theme pierrette.gaudreau@umontreal.ca

  • Dr. Petronela Ancuta

Immunopathology Research Theme petronela.ancuta@umontreal.ca

  • Dr. Catherine Larochelle

Neuroscience Research Theme catherine.larochelle.chum@ssss. gouv.qc.ca

  • Dr. Marie-Pierre Sylvestre

Health Innovation and Evaluation Hub marie-pierre.sylvestre@umontreal.ca

  • Dr. Pierre Drapeau

Neuroscience Research Theme p.drapeau@umontreal.ca

  • Dr. Karl Fernandes

Neuroscience Research Theme karl.jl.fernandes@umontreal.ca

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STUDENT MEMBERS OF THE STUDENT AFFAIRS COMMITTEE

Ju Jing Tan, Student Immunopathology Research Theme President of the CRCHUM Student Committee jujingtan@gmail.com Valérie Bergeron, Student Cardiometabolic Research Theme Doctoral Student Representative valerie.bergeron.2@umontreal.ca Damien Adam, Student Immunopathology Research Theme Postdoctoral Student Representative damien.adam@inserm.fr

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  • 1. To inform (e.g., welcome session, external

grant programs, courses)

  • 2. To guide, advise and support (e.g., one-on-
  • ne meetings, official signing of grant

applications, internship agreements, etc.)

  • 3. To encourage scientific discussions (e.g.,

The CRCHUM’s 9th Scientific Day (26/10/2018), Annual Student, Fellow and Resident Symposium (03/05/2018)

  • 4. To showcase your research results (e.g. travel

grants – Conferences – CRCHUM Challenge (2 competitions/year: 17/08/2018 and 11/01/2019)

NEED ADVICE? HAVING PROBLEMS? CONTACT THE ASSOCIATE SCIENTIFIC MANAGEMENT OFFICE– STUDENT AFFAIRS

MISSION

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  • 1. To encourage excellence (e.g., training

awards, excellence grants, doctoral recruitment scholarships)

  • 2. To support through the development of a new

student guide – in the final phase of production; annual grant application and CCV preparation clinics

  • 3. To promote the development of a feeling of

belonging and involvement – organization of scientific activities in collaboration with the Student Committee

  • 4. To offer activities meant to develop cross-

cutting and complementary skills – collaboration with the teaching department and the CHUM Academy

NEED ADVICE? HAVING PROBLEMS? CONTACT THE ASSOCIATE SCIENTIFIC MANAGEMENT OFFICE– STUDENT AFFAIRS

MISSION

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PSYCHOLOGICAL DISTRESS

  • 1. Student Affairs Department
  • 2. The CRCHUM Student Committee
  • 3. Contact the Université de Montréal’s

Student Health Centre at 514-343-6452 and mention that you need immediate care.

http://www.cscp.umontreal.ca/activitepreve ntion/activites_prevention.htm

4. In situations involving loss of appetite, refusal to eat,

  • r suicidal thoughts, it is important to go the CHUM’s

emergency service or that of another hospital, if the student has a file open there.

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http://crchum.chumontreal.qc.ca TABS

  • CHUM
  • RESEARCHERS
  • RESEARCH THEMES
  • CLINICAL RESEARCH
  • CORE FACILITIES AND SERVICES
  • STUDENTS
  • PROCEDURE FOR STUDYING AT THE

CRCHUM

  • AWARDS AND GRANTS
  • STUDENT LIFE
  • STUDENT CONFERENCE
  • OPEN HOUSE DAY
  • NEWS
  • ABOUT

INFORMATION

ASSOCIATE SCIENTIFIC MANAGEMENT TEAM – STUDENT AFFAIRS

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STUDENT COMMITTEE

Ju Jing Tan President of the Committee PhD student

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STUDENT COMMITTEE

Members:

President Ju Jing Tan Treasurer Anindya Ghosh Secretary Déborah Beillevaire Vice President François Michaud

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STUDENT COMMITTEE

Representatives:

Doctorate Valérie Bergeron Postdoctorate Damien Adam Master’s Lojan Sivakumaran Substitute (Doctorate) Elsa Brunet Ratnasingham Substitute (Master’s) Yanick Lee

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STUDENT COMMITTEE

Henry Yat Hei Leung Valentin Teyssier

Activities and recreation: Communications: Other members:

Cayetana Vazques Castro Diez Marius Tresor Chiasseu Mbeumi Louise Leyre Pol Grasland-Mongrain

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STUDENT COMMITTEE

Objectives:

  • To create a feeling of belonging among students at the

CRCHUM

  • To organize scientific, academic and social events
  • To advocate for students’ interests
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STUDENT COMMITTEE

Monthly activities:

  • Student presentations
  • Movie night
  • Happy hour
  • Other activities (to come)

UQAM Sports Centre:

  • http://sports.uqam.ca/
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STUDENT COMMITTEE

Training and workshops (coming soon!):

  • To develop better scientific practices
  • Imaging
  • Data production and processing
  • Biostatistics
  • Scientific communications
  • Writing articles

Project subsidized as part of the ‘’Programme d'appui aux initiatives de soutien à la réussite’’ (2017)

http://reussir.umontreal.ca/projets/appui-aux-initiatives/developper-de-meilleures-pratiques-scientifiques/

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STUDENT COMMITTEE

Volunteering at the CRCHUM:

  • Open House Day
  • The CRCHUM’s Networking Cocktail Event
  • And many other opportunities…
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STUDENT COMMITTEE

Announcement:

  • General Assembly
  • Tuesday, February 13, 2018
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STUDENT COMMITTEE

To contact us:

  • Facebook:
  • http://www.facebook.com/EtudiantsCrchum
  • http://www.facebook.com/groups/etudiantsducrchum
  • Search for Étudiants du CRCHUM
  • E-mail:
  • comite.etudiant.cr.chum@ssss.gouv.qc.ca
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DEPARTMENT OF HUMAN RESOURCES

Christine Bellefeuille Senior Human Resources Advisor

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The CRCHUM… SCIENTIFIC LIFE: 6 areas 2,000 PEOPLE RESEARCH CONTINUUM INTERNATIONAL VOCATION

DEPARTMENT OF HUMAN RESOURCES

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What you need to know…

 PHOTO ID CARD  ACCESS SWIPE CARD  USER CODE OR ‘’P’’ CODE  LIABILITY INSURANCE  CSST  EMPLOYMENT CONTRACT  LOCKERS/LAB COATS  CONFIDENTIALITY  STUDENT CENSUS/GRADUATION  SCHOLARSHIPS – TAX IMPLICATIONS  RESPONSIBLE CONDUCT TRAINING  ASSISTANCE PROGRAM  CONFLICTS OF INTEREST  PARKING/TRANSPORTATION

CONTACT INFORMATION Christine Bellefeuille – ext. 15515 Irena Mrkonjic – ext. 26926 Brigitte Lamy – ext. 15514

DEPARTMENT OF HUMAN RESOURCES

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THE CRCHUM’S CORE FACILITIES

Alignment and use of shared resources Céline Coderre Manager – Scientific Performance

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Animal facility Biobanks Cytometry, cell imaging and molecular pathology Experimental imaging BSL3 (BioSafety Level 3) MeDIS (Metabolic Disease Innovative Solutions)

  • Rodent phenotyping
  • Metabolomics and cellular physiology
  • Pharmacokinetics

Radiochemistry and cyclotron Surface plasmon resonance (Biacore) Transgenesis and animal modelling ECRU (early clinical research unit)

THE CRCHUM’S CORE FACILITIES

Bioinformatics Biostatistics Scientific writing

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THE CRCHUM’S CORE FACILITIES

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THE CRCHUM’S CORE FACILITIES

Why use the core facilities?

  • Specialized expertise on site to develop your projects
  • Quick delivery of services
  • Training for self-serve activities and technical support
  • High-performance, well-maintained equipment
  • Modest, subsidized costs
  • Data analysis
  • Collaboration in preparing your publications

Importance of acknowledging the core facilities in publications Beneficial for you, your group, the CRCHUM

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Cytometry, cellular imaging and molecular pathology

Cytometry: NEW ANALYZER coming

CELL SORTING (NC1 and NC3) and MULTIPARAMATER CELLULAR ANALYSIS 2 sorters (4 lasers, 15 colours, sterile and RNAse-free) 3 analyzers: LSR II: 4 lasers - 16 colours 3 lasers - 14 colours, 5 lasers – 18 colours

Cellular Imaging:

(NC1 and 2) Intravital fluorescence confocal microscopy IMARIS image analysis software - NEW

Molecular pathology:

Immunohistochemical and H&E staining Paraffin and frozen tissue sectioning Construction of tissue microarrays (TMAs) Immunohistochemistry, immunofluorescence Bright field and fluorescent slide scanning Assistance from CHUM pathologists

THE CRCHUM’S CORE FACILITIES

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Biobanks

Our new core facility since December 15, 2017 A dedicated floor at Montreal’s Hôtel-Dieu Hospital Pathology blocks, mainly cancer, at the present time Spaces for biobanks in -80C freezers Spaces for liquid nitrogen tanks Secure environment, equipment maintained Alarm system with e-mail or phone notifications Assistance for sample and transportation management CL3 (Containment level 3): Controlled environment and access 8 culture rooms Cytometry – cell sorter Sample storage room

THE CRCHUM’S CORE FACILITIES

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Radiochemistry and cyclotron

  • Research & Development

– Organic & Analytic Chemistry

  • Precursor & Standard synthesis

– Radiochemistry – Biotesting & analysis of radioactive metabolites

  • Services offered

– Production (Carbon-11, Fluorine-18 and Nitrogen-13) – Existing radiotracers ([18F]DCFPyL, [18F]Choline, [18F]HFB, [13N]NH4Cl, [18F]FTHA) – New radiotracers ([18F]DMDA, [18F]Fluoropyridine-Losartan, NEP derivates) – Quality control of PET radiotracers and organic molecules – Submission of Clinical Trial Applications (CTAs) to Health Canada

THE CRCHUM’S CORE FACILITIES

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Animal Facility:

Environment with considerable expertise for successfully carrying out your research project with due regard to the animals and their welfare

Transgenesis and animal modelling:

Generation of transgenic mice and rats CRISPR/Cas/9 technology Rodent genotyping Stem cell microinjections Stem cell electroporation Stem cell karyotyping Embryo cryopreservation, thawing and transfer

Experimental imaging:

Animal and human 3T MRI CT-Angiography Ultrasound system MicroPET/CT

THE CRCHUM’S CORE FACILITIES

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Rodent Phenotyping

Metabolics: Pancreatic islet isolation Insulin secretion on cell line, isolated pancreatic islets and in situ pancreas In vivo carbohydrate homeostasis In vivo energy metabolism Blood biochemistry Experimental models Cardiovascular: ART Optix MX2 small animal imaging Micro-CT scanner EchoMRI magnetic resonance imaging Rodent surgery and telemetry Metabolic cages Behavioural: Radial Arm Maze Elevated Plus Maze Morris Water Maze Novel Object Recognition and Open field testing devices Physioscan and DietMax Cages Instruments for measuring motor coordination and strength (RotaRod) CatWalk gait analysis Treadmill exercisers

THE CRCHUM’S CORE FACILITIES

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Metabolomics and cellular physiology:

Targeted and quantitative MS analysis of soluble small-molecule metabolites and known lipids Discovery of new metabolites SeaHorse analyzer – O2 consumption and CO2 production Operetta – proliferation, apoptosis, migration, ROS, membrane potential, mitochondrial mass Luminex – Analysis of blood parameters by analyzer Quantification of analytes and hormones by ELISA and AlphaLIS

Pharmacokinetics:

In vitro metabolism (S9 fraction, microsomes, hepatocytes) Assessment of membrane transport Transfer, development, optimization and validation of methods PD bioanalysis (biomarkers) PK bioanalysis

Surface plasmon resonance:

Mesurement of different protein interactions (BiaCore 3000)

THE CRCHUM’S CORE FACILITIES

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Biostatistics: Writing funding applications and protocols Reviewing and critiquing various scientific documents (grants, articles, protocols) Project planning Advice on the direction of the project Calculation of sample size Data analysis Collaboration on publications Interpretation of results Personalized workshops (short seminar, facilitation of journal clubs, statistics workshops).

THE CRCHUM’S CORE FACILITIES

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Bioinformatics: Automation of analysis Support for the use of bioinformatics software Analysis of large datasets High-performance computing Database construction and maintenance Project consultation Web tool creation Scientific writing: Reviewing documents to identify weaknesses Reviewing to improve presentation, grammar and syntax Reviewing more thoroughly and recommending improvements in content Assistance in writing new documents

THE CRCHUM’S CORE FACILITIES

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THE CRCHUM’S CORE FACILITIES UPCOMING ACTIVITIES

EXPERIMENTAL IMAGING – January 25 Presentation on the areas of study and treatment that use magnetic stimulation MOLECULAR PATHOLOGY – February 1 Optimize your manipulations: immunohistochemistry, immunofluorescence, image processing and more CONFINEMENT LEVEL 3 – February 8 Presentation of the HIV-Primo and HIV-Aging cohorts RADIOCHEMISTRY AND CYCLOTRON – March 15 Translational studies that complement your research through the use of radioligands and PET imaging

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http://crchum.chumontreal.qc.ca/plateformes-et-services

 Presentation of each core facility  Contact information of technical and scientific managers  Policies – procedures - pricing Check it out regularly! French and English versions

Registration forms

 To fill out an application to use a facility or a service, contact the technical manager  Payment authorization to be signed by the researcher

THE CRCHUM’S CORE FACILITIES Website and registration

COORDINATOR’S CONTACT INFORMATION Céline Coderre – ext. 30673 celine.coderre.chum@ssss.gouv.qc.ca

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ANIMAL FACILITY

Hélène Héon Veterinarian and Head of the Facility

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38 members Animal health technicians Animal care providers Sterilization attendant Manager’s assistants Weekend staff Veterinarians

ANIMAL FACILITY

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Ensures animal maintenance, care and welfare Provides assistance for research projects Treatments Animal orders and import/export Hands-on training

ANIMAL FACILITY

TECHNICAL SERVICES

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 Embryo transfers  Embryo and sperm cryopreservation  In vitro fertilization  Generation of transgenic or knock-out mice and rats (pronuclear microinjections, ES cells)  CRISPR/Cas9 nucleases, Zinc Finger Nucleases (ZFNs) and Transcription Activator-Like Effector Nucleases (TALENs)  Preparation of DNA for microinjections  Preparation of ES cells  Karyotyping

ANIMAL FACILITY

ANIMAL MODELING CORE FACILITY

CONTACT INFORMATION Jean‐François Schmouth, ext. 35224

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 Oversees the quality of care given to animals housed at the CRCHUM  Provides project planning support (surgery, anaesthesia, animal care and supervision, endpoints, animal models, etc.)  Animal care service

ANIMAL FACILITY

VETERINARY DEPARTMENT

CONTACT INFORMATION Hélène Héon – ext. 28867 Maryse Boulay – ext. 23719

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13th floor

 Rodent imaging  Large animal surgery and imaging room  Accommodations for large animals and fish  Quarantine  Culture room  Instrument washing room  Large animal necropsy room

ANIMAL FACILITY

HOUSING AND SHARED PREMISES

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14th floor

 Rodent housing and manipulation room  Animal modelling core facility  Rodent surgery-telemetry-physiology room  Equipment washing room (cages, bottles, etc.)  Rodent necropsy room

ANIMAL FACILITY

HOUSING AND SHARED PREMISES

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Mice Rats Rabbits Dogs Pigs Fish The animals are healthy; there is no danger of transmission of diseases to humans Some people may develop an allergy to rodents and rabbits

ANIMAL FACILITY

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Available to researchers, animal users and collaborators Hours of operation: 6:30 a.m.- 8:00 p.m. Housing rooms accessible from 6:30 a.m. - 6:30 p.m. Training required Programming of swipe cards depending on sectors covered

ANIMAL FACILITY

CONTACT INFORMATION Cordélia Cadieux – ext. 28938

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 INTRANET  ANIMAL FACILITY – CIPA  ANIMAL FACILITY

  • Policies and procedures (animal facility and

CIPA)

  • Department contact information
  • Per diem list
  • Animal modelling core facility list
  • Forms
  • Helpful links

ANIMAL FACILITY

DOCUMENTATION

 CIPA  USER TRAINING  HEALTH AND SAFETY

  • Biohazard committee
  • Radiation Protection Service
  • Hazardous material
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INSTITUTIONAL ANIMAL PROTECTION COMMITTEE

Christian Demers Coordinator Animal Protection Committee

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INSTITUTIONAL ANIMAL PROTECTION COMMITTEE

WHO IS CONCERNED BY THE CIPA? All people who will be working on protocols using research animals. The CIPA is a committee that reviews protocols by assessing the expected benefits for the improvement of human or animal health and well-being.

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POLICIES AND GUIDELINES OF THE CANADIAN COUNCIL ON ANIMAL CARE (CCAC) http://www.ccac.ca

INSTITUTIONAL ANIMAL PROTECTION COMMITTEE

BASIS FOR THE CIPA’S POLICIES

CONTACT INFORMATION Coordinator: Christian Demers – ext. 28947 Assistant: Geneviève Lauzon – ext. 24535 cipa.chum@ssss.gouv.qc.ca

The CCAC certifies our animal care and use program every three years on the basis of its compliance with the policies and guidelines of the CCAC and other standards recognized by the CCAC.

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 COMMON CORE  LOCAL PROCEDURES/ORIENTATION/WELCOME TO THE ANIMAL FACILITIES  LABORATORY PRACTICES (MICE, RATS, ASEPTIC SURGERY, ETC.)

INSTITUTIONAL ANIMAL PROTECTION COMMITTEE

MANDATORY TRAINING FOR ANIMAL USERS

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After an information session, you can become a volunteer and come play with the dogs and cuddle them. If this interests you, please contact the CIPA or the Animal Facility.

INSTITUTIONAL ANIMAL PROTECTION COMMITTEE

VOLUNTEERING

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LABORATORY SAFETY AND BIOHAZARDS

Laurent Knafo Health and Safety Advisor

CONTACT INFORMATION Laurent Knafo – ext. 26537 Laurent.knafo.chum@ssss.gouv.qc.ca

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LABORATORY SAFETY AND BIOHAZARDS

 EMERGENCY MEASURE PLAN  GENERAL BIOSAFETY  CONFINEMENT LABORATORIES

TRAINING

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HAZARDOUS MATERIAL TRANSPORTATION

OTHER IMPORTANT TRAINING

LABORATORY SAFETY AND BIOHAZARDS

WHMIS RADIATION PROTECTION

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 MICROORGANISMS (VIRUSES, BACTERIA, ETC.)  HUMAN ANATOMICAL SPECIMENS  CELL CULTURES  VIRAL VECTORS AND RECOMBINANT DNA  TOXINS  CYTOTOXIC DRUGS  CHEMICALS

LABORATORY SAFETY AND BIOHAZARDS

BIOHAZARDS

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LABORATORY SAFETY AND BIOHAZARDS

BIOSAFETY MANAGEMENT

 CRCHUM’s management team  Institutional biosafety committee  Biological safety agent  Students/Interns/Research assistants…  Federal and provincial agencies (PHAC/CFIA/Transport Canada/Environment Canada)

BIOSAFETY MANAGEMENT

 CRCHUM’s management team  Institutional biosafety committee  Biological safety agent  Students/Interns/Research assistants…  Federal and provincial agencies (PHAC/CFIA/Transport Canada/Environment Canada)

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LABORATORY SAFETY AND BIOHAZARDS Biosafety

Administrative controls Personal protection equipment Practices and procedures Engineering controls

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Policies in effect at the CRCHUM  No: 90420 (dress code)  No: 90460 (disciplinary measures)

LABORATORY SAFETY AND BIOHAZARDS

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IN CASE OF EMERGENCY

YOUR SAFETY = YOUR PRIORITY

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LABORATORY SAFETY AND BIOHAZARDS

MANDATORY REPORTING OF INCIDENTS/SPILLS

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THE CHUM LIBRARY

Daniela Ziegler Librarian-Informationist

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RESEARCH ETHICS BOARD FOR RESEARCH WITH HUMAN PARTICIPANTS (REB) Marie-Josée Bernardi, Attorney

ACTING CHAIRPERSON OF THE REB

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TO ENSURE THE PROTECTION OF RESEARCH PARTICIPANTS Respect for their dignity and safety

  • Autonomy

free, informed consent

  • Integrity

evaluate and minimize risks

  • Privacy

confidentiality of data

RESEARCH ETHICS BOARD (REB) MISSION

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 TO EVALUATE RESEARCH PROJECTS WITH HUMAN PARTICIPANTS

  • Approve
  • Reject
  • Approve conditionally

 PROJECT MONITORING  TRAINING OF RESEARCHERS

RESEARCH ETHICS BOARD (REB) MANDATE AND

AUTHORITY

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 LIVING INDIVIDUALS  CADAVERS AND HUMAN REMAINS, BIOLOGICAL TISSUES AND FLUIDS, GAMETES, EMBRYOS OR FOETUSES  PERSONAL INFORMATION CONTAINED IN MEDICAL FILES

RESEARCH ETHICS BOARD (REB) RESEARCH WITH HUMAN PARTICIPANTS

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WHAT PROJECTS NEED TO BE PRESENTED TO THE REB?  Carried out, in whole or in part, within the establishment  Including participants recruited among CHUM users or workers or from files kept by the establishment  For projects receiving funding from private industry or a public funding agency that involve the participation of the establishment and/or a researcher affiliated with the establishment  Using the CHUM’s human, material or financial resources

RESEARCH ETHICS BOARD (REB) ANY RESEARCH PROJECT

WITH HUMAN PARTICIPANTS

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 PROJECT SUBMITTED VIA THE NAGANO PLATFORM:

  • Code p
  • Access request

 HOW TO PREPARE:

  • Informed consent form models (standard clauses)

RESEARCH ETHICS BOARD (REB) HOW TO SUBMIT A PROJECT TO THE REB?

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 HOW TO SUBMIT PROJECTS:

  • GUIDE FOR RESEARCHERS for the evaluation and

monitoring of single- and multi-centre projects at the CHUM’s REB, which includes the new ministerial framework (revised version dated April 1, 2016)

  • REB RESOURCE PERSONS

Don’t hesitate to contact us!!!

RESEARCH ETHICS BOARD (REB) HOW TO SUBMIT A PROJECT TO THE REB?

CONTACT INFORMATION: ext. 14485

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Communications and events

Mireille Chalifour Chanel Lavoie

Scientific events and activities E-mail communications

Isabelle Girard

News, videos

Lauréanne Marceau

Web and social media

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Visibility of the CRCHUM’s research activities

  • Dissemination of news and news briefs:

scientific breakthroughs, innovations, tributes, grants, publications

  • Connexions E-newsletter
  • Scientific activity newsletter
  • The CHUM’s intranet, the Université de

Montréal’s website, etc.

  • Social media: Follow us on Facebook

and Twitter

  • The CRCHUM’s website
  • Videos
  • Collaboration with CHUM

communications (Intranet, postings, etc.) and the Université de Mtl.

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CRCHUM Scientific Day

2010: Dr. Françoise Barré Sinoussi, winner of the 2008 Nobel Prize in Medicine 2011: Dr. Lee Hartwell, winner of the 2001 Nobel Prize in Medicine 2012: Dr. Ferid Murad, winner of the 1998 Nobel Prize in Medicine 2013: Dr. Jules Hoffmann, winner of the 2011 Nobel Prize in Medicine 2014: Dr. Pierre Corvol, Professeur Emeritus at the Collège de France 2015 : Robert J. Lefkowitz, winner of the 2012 Nobel Prize in Chemistry 2016 : Peter Charles Doherty, winner of the 1996 Nobel Prize in Medicine 2017: Andrew Z. Fire, winner of the 2006 Nobel Prize in Medicine

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SLIDE 113

CRCHUM Conferences Fridays at noon

  • February 2, 2018

Susan Bonner‐Weir, Ph. D.

Senior Investigator, Joslin Diabetes Center and Professor of Medicine, Harvard Medical School, Guest Speaker for the Montreal Diabetes Research Center’s 2018 Scientific Day

  • February 23, 2018

Janice Robertson, Ph. D.

Tanz Centre for Research in Neurodegenerative Disease, University of Toronto Amyotrophic Lateral Sclerosis and Frontotemporal Dementia: A Disease Spectrum

  • Complete lineup: CRCHUM website
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SLIDE 114

 5K, 10K and 21K run or walk and a kid’s race  Parc Jean-Drapeau  April 21-22, 2018  In 8 years, $675K collected Reinvestment of proceeds  25% for the creation of a student scholarship fund for participating in scientific conferences  Other funds are reinvested in research at the CRCHUM

CRCHUM CHALLENGE Marathon/half-marathon

5K, 10K or 21K and a kid’s race

The CRCHUM CHALLENGE: members of the CHUM mobilize

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SLIDE 115

 First Open House activity – Sept. 2017  Goal: to help with the recruitment of new students  45 students participated in setting up booths and conducting visits

Open House Day at the CRCHUM

September 22, 2018

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SLIDE 116

Technology Transfer and Research Contracts Office (TTRCO)

Juliana Lanza Team Leader, Contract Manager TTRCO, CRCHUM Grazia Maion Vice President, Business Development, Univalor

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SLIDE 117

Adolpho Faria Contract Manager Eliane Brunello Contract Manager Paula Hirata Contract Manager

Technology Transfer and Research Contracts Office (TTRCO) CONTRACT REVIEW, DRAFTING AND NEGOTIATION

Janie Poirier Contract Manager

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SLIDE 118

Technology Transfer and Research Contracts Office (TTRCO) THE TTRCO IN NUMBERS (2016-2017)*

  • 818 contracts signed
  • 47 contracts in the process of being signed
  • 133 contracts cancelled or suspended
  • 374 contracts in negotiation

* as of March 31, 2017

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SLIDE 119

 MTA (Material Transfer Agreement)  CDA (Confidential Disclosure Agreement)  Contracts with industry  Academic collaborative contracts and collaborative contracts with industry  Interinstitutional contracts  And all other contracts/agreements involving CRCHUM researchers

  • r projects

* Clinical and basic research

Technology Transfer and Research Contracts Office (TTRCO) CONTRACT/AGREEMENT TYPES*:

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SLIDE 120

Technology Transfer and Research Contracts Office (TTRCO) SUBMITTING A CONTRACT FOR REVIEW:

Clinical: submit the contract to Nagano + send an e-mail to the TTRCO

(see the Guide for researchers and their team – Version 04 – June 8, 2017)

Non-clinical: contact the TTRCO Contact the TTRCO

contrats.chum@ssss.gouv.qc.ca Paula Hirata: 15523

REQUEST FOR CONTRACT DRAFTING:

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SLIDE 121

TRANSFER

TRANSFERRING RESEARCH RESULTS TO SOCIETY Transferring means giving added value to usual university research activities and their results

 Scientific publications and communicatiions  Training and teaching  Research contracts  Research partnerships  Consulting and training contracts  Technological transfer  Student training  Knowledge transfer  Commercialization  Business creation

Technology Transfer and Research Contracts Office (TTRCO)

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SLIDE 122

WHO OWNS INTELLECTUAL PROPERTY? (according to the regulation on IP for CHUM research results) The 1st owner of the intellectual property is the creator (or inventor) of the intellectual property. The researcher and the CRCHUM/Université de Montréal are undivided co-

  • wners.

For purposes of commercial exploitation, the inventor must disclose the invention to the CRCHUM by filling out an invention/innovation disclosure (ID) form.

* researcher = doctors, staff members, research assistants, postdoctoral fellows and students, individuals holding university status from a university and who conduct their research and teaching activities mainly at the CRCHUM

TRANSFERRING RESEARCH

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SLIDE 123

NO CONTRACT SHALL RESULT IN PREVENTING: The CHUM from using, for teaching, research and non- commercial purposes, the results stemming from research work; university researchers from publishing the results of their research; and students from publishing their theses, all in accordance with the applicable rules adopted by the University.

TRANSFERRING RESEARCH

IN THE CONTEXT OF THE COMMERCIAL EXPLOITATION

OF IP BY THE CHUM

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SLIDE 124

MORE THAN ONE PATH TO COMMERCIALIZATION

LICENCE

Create partnerships and collaborate with industry to develop and market your technology.

ON‐LINE SALES

If you’ve developed software, applications or electronic documents that are suitable for

  • nline distribution, you can commercialize them to targeted markets with eValorix.com.

CREATION OF A SPIN‐OFF COMPANY

Support your entrepreneurial spirit and guide you as you start your business.

TRANSFERRING RESEARCH

COMMERCIALIZATION PARTNER

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SLIDE 125

UNIVALOR’S TRANSFER PROCESS

IP

Science Market

  • Patentability
  • Robustness
  • The team’s expertise
  • Strong proof of concept
  • Suitable model? Clinical application?
  • Business development
  • Short/long-term market
  • Feasibility
  • Advantages vis-à-vis the competition
  • SWOT analysis, business plan
  • Novelty, Utility, Ingenuity

COMMERCIALIZATION PARTNER

TRANSFERRING RESEARCH

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SLIDE 126

PATENTABILITY CRITERIA

  • 1. NOVELTY

No previous public disclosure prior to the filing date of the patent

  • 2. UTILITY

Realistic, functional application

  • 3. INGENUITY

Peer-reviewed non-obviousness THE LAW STIPULATES THAT, TO BE PATENTABLE, AN INVENTION HAS TO MEET THREE REQUIREMENTS: COMMERCIALIZATION PARTNER

TRANSFERRING RESEARCH

UNIVALOR’S TRANSFER PROCESS

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SLIDE 127

TRANSFERRING RESEARCH

COMMERCIALIZATION PARTNER

UNIVALOR’S TRANSFER PROCESS

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SLIDE 128

www.mitacs.ca/fr

128

www.mitacs.ca/fr

SUPPOR T ING UNIVE R SIT Y R E SE AR CH T HR OUGH PAR T NE R SHIPS

Nadia Dubé, Ph. D., Business Development Specialist Mitacs ‐ Université de Montréal ndube@mitacs.ca (514) 701‐1727

New CRCHUM student welcome session January 26, 2018

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SLIDE 129

www.mitacs.ca/fr

129

On the pr

  • gr

am

Why Mitacs? The different programs

– Partnership:

 In Canada  Abroad

– University research abroad:

 Research scholarships

– Pilot program:

 Development of Canadian policies

– Workshops/advanced training

Summary

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SLIDE 130

www.mitacs.ca/fr

130

Why Mitac s?

National research network offering research support programs (all disciplines) Supporting innovation for 18 years 20,000+ research projects 60+ university partners Funding

– Federal: $221M over a 5‐year period – Provincial: $50M over a 5‐year period

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SLIDE 131

www.mitacs.ca/fr

131

Mitac s in figur e s

Sustained inc r ease in funding

# of Mitacs‐funded research projects

Target 10,000: talent, ideas, networks 10,000 research projects annually by 2020

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SLIDE 132

www.mitacs.ca/fr

132

Mitac s pr

  • gr

am goals

Industry

Support flexible, collaborative research initiatives in all disciplines Attract new funding Train graduate students and postdoctoral researchers for their careers

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SLIDE 133

www.mitacs.ca/fr

133

Par tne r ships in Canada

Standard Accelerate

Research projects as university‐organization partnerships Graduate students and postdoctoral researchers Applications accepted throughout the year

Foreign students eligible  Private and non‐profit sectors

M.Sc. & D.E.S.S.: 2 units Ph.D. and postdoc: 6 units

$15,000 for 4 months

$7,500 Partner $7,500 Mitacs

$10,000

Salary (min.)

$5,000

Research expenses

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SLIDE 134

www.mitacs.ca/fr

134

Par tner ship in Canada  Private and non‐profit sectors

$40,000 for 18 months

$18,000 Partner $22,000 Mitacs

$30,000

Salary (min.)

$10,000

Research expenses

Accelerate – Master’s scholarship Accelerate – Ph.D. scholarship $80,000 for 36 months

$36,000 Partner $44,000 Mitacs

$72,000

Salary (min.)

$8,000

Research expenses

 Vocational training (workshops)

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SLIDE 135

www.mitacs.ca/fr

135

Par tne r ships in Canada

Elevate

Research projects as university‐organization partnerships

Postdoctoral researchers only

Vocational training (workshops)

Applications selected on a competitive basis  Private and non‐profit sectors

$60,000/year, for 2 years

Salary for the postdoctoral researcher $55,000 /year Other expenses $5,000/year Total value of the training program $15,000 Annual contributions

$30,000 from the partner $30,000 from Mitacs ( + training workshops valued at $7,500)

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SLIDE 136

www.mitacs.ca/fr

136

Par tne r ships abr

  • ad

Accelerate International

Research projects as university‐company partnerships

Graduate students

All countries  Private sector

Globalink partnership scholarship

$15,000 for 4 months

$7,500 Partner $7,500 Mitacs

$10,000

Salary (min.)

$5,000

Research expenses

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SLIDE 137

www.mitacs.ca/fr

137

E ligible par tne r s

Ac c e le r ate

  • Governments (federal,

provincial, municipal)

  • Hospitals

Private businesses, State‐owned companies Non‐ governmental

  • rganizations

(NGOs) Nonprofit

  • rganizations

(NPOs)

Ex.: associations (industrial, professional, etc.)

Not eligible:

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SLIDE 138

www.mitacs.ca/fr

138

  • 1. Contact me: eligibility of the partner organization
  • 2. Be enrolled full‐time
  • 3. The partner agrees to contribute financially
  • 4. Project = research & relevant for both parties
  • 5. Possibility of working at the partner organization
  • 6. File the applciation 8‐10 weeks before the start of the project

6 points to c onsider :

Ac c e le r ate

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SLIDE 139

www.mitacs.ca/fr

139

 Globalink research scholarships

Univer sity r esear c h abr

  • ad - Globalink

Program Eligibility

  • Inter‐university collaboration
  • Current partners: Saudi Arabia, Australia,

Brazil, China, Korea, the U.S., India, Israel, Japan, Mexico, Norway, Tunisia, the U.K., the E.U.

  • $5,000 ‐ $10,000
  • 5,000 AUD + 3,000 AUD/month
  • Deadline: June
  • Call for applications: from Nov. 1 to Dec. 15
  • $5,200 (travel and accommodations)
  • Biology, chemistry, physics, engineering, earth

sciences ,

  • Humanities, social science, natural sciences
  • Travel expenses + allowance
  • Canadian citizens and permanent residents
  • Call for applications: ends in November
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SLIDE 140

PREPARING TRAINING GRANT APPLICATIONS

Pierrette Gaudreau, PhD Assistant Scientific Director – Student Affairs President of the Student Affairs Committee

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SLIDE 141

HOW TO PREPARE A WINNING TRAINING GRANT APPLICATION

  • r

TIPS AND TRICKS TO MAXIMIZE YOUR CHANCES OF SUCCESS

Pierrette Gaudreau Ph. D. Ex-Scientific Advisor Fonds de Recherche du Québec-Santé Full Professor, Department of Medicine, Université de Montréal and Director of the Neuroendocrinology of Aging Laboratory, University of Montreal Hospital Research Centre October 6, 2017

PREPARING TRAINING GRANT APPLICATIONS

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SLIDE 142

To learn how to better prepare a high-quality training grant application To become aware of the errors commonly found in research project descriptions To learn how to add value to your CV

PREPARING TRAINING GRANT APPLICATIONS

OBJECTIVES

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SLIDE 143

PREPARING TRAINING GRANT APPLICATIONS

START EARLY

 To initiate a discussion with your research director and identify the organizations/foundations where you have the best chances of succeeding

 Before the summer vacation period

 To become thoroughly familiar with the description of the different programs available for the fall 2018 competition

  • Usually June-July
  • An annual competition

 Deadlines and special procedures:

  • FRQS:
  • October 16, 2018 (4:30 p.m.) – Training grants, M. Sc., Ph. D. and postdoctoral
  • Doctoral training for foreign students (MEES program administered by the FRQNT),

early August 2018, visit your university’s grant department for information on the deadline for the internal preselection competitions

  • CIHR:
  • December 1, 2018 – Master’s training award (evaluation at the institutional level)
  • October 4, 2018 – Doctoral training award, regular competition
  • November 1, 2018 – Postdoctoral training awards, regular competition
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SLIDE 144

 To establish a timetable of deliverables  If the deadline is October 16, 2018, your grant application should be completed by September 30th

  • Allow enough time for a final rereading
  • Yourself
  • Your director and co-director

 Very often the time needed to produce a quality application is underestimated! A tip: estimate the time required to the best of your knowledge (including entering data and pdf documents into the organization’s website) and multiply this by 2.5

PREPARING TRAINING GRANT APPLICATIONS

START EARLY

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SLIDE 145

PREPARING TRAINING GRANT APPLICATIONS

THE PROGRAM FACT SHEETS FOR THE 2018-2019 FUNDING

YEAR ARE AVAILABLE – WHERE SHOULD YOU START?

 Read ALL the information/documents needed for your grant application:

  • Program description and objectives
  • Eligibility rules (form to calculate the number of sessions)
  • Specific instructions
  • Filing and evaluation processes
  • Selection of disciplinary adjudication committee
  • Description of partnerships

 Make a final determination of what programs you are eligible for  Choose the organizations/agencies/foundations that you can apply to  Familiarize yourself with the different tools that you’ll use for your application (Research Net, latest version of the Canadian Common CV, electronic filing system, etc.)  Establish a final timeline with deliverables and draw up a checklist

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SLIDE 146

PREPARING TRAINING GRANT APPLICATIONS

THE 1ST VERSION OF YOUR RESEARCH PROJECT

 FIRST AND FOREMOST, TALK TO YOUR DIRECTOR!  Your project has to comply with the organization’s evaluation criteria and guidelines  Example: FRQS

  • Provide a clear description of your research project, specifying, in order:
  • Research problem (literature review, your host laboratory’s contribution to the field, show the

importance of your subject with respect to these pieces of information)

  • Hypotheses and objectives
  • Methods and analyses
  • Feasibility
  • Contribution to the advancement of knowledge
  • Maximum of 6 bibliographic references
  • A 2-page PDF document (page size: 8 1/2 x 11) is allowed.
  • The text can be written in French or English (title in French). The document must be very readable

and comply with the following guidelines:

  • Font type and size: 10 pt. Arial or 12 pt. Times New Roman
  • Single-spaced; minimum 2 cm page margins; page numbers in the footer
  • Last name, first name and file number in the header of each page
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SLIDE 147

 Poorly-planned use of the 2 pages allowed

 One full page for the problem – not enough space to develop the other sections

  • ¾ of a page for the list of references (6 key references are sufficient)
  • ½ page empty –
  • SENDS THE EVALUATORS A NEGATIVE MESSAGE
  • Declutter your layout: give titles to the project sections, make paragraphs

 No hypothesis stated or an unclear hypothesis  Lack of coherence between the hypothesis(es) and the objectives, lack of clarity  Undeveloped methods (e.g., use of new techniques/state-of-the art tool/sector-specific competencies; characteristics of the population sample, justification of sample size,confounding bias/variables, etc.)

PREPARING TRAINING GRANT APPLICATIONS

COMMON ERRORS IN WRITING THE RESEARCH PROJECT

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SLIDE 148

 Lack of justification of the methods of analysis chosen  No description of the statistical analyses  Lack of justification of the techniques chosen  Originality and Contribution to the Advancement of Knowledge section missing or vague  Undefined acronyms – overuse (specialist jargon)  Poor writing quality – use short, clear sentences without French or English errors and without typographical errors – reread what you wrote and have someone else reread it!  Don’t copy and paste your director’s 5-year research program!

PREPARING TRAINING GRANT APPLICATIONS

COMMON ERRORS IN WRITING THE RESEARCH PROJECT

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SLIDE 149

PREPARING TRAINING GRANT APPLICATIONS

THE CANADIAN COMMON CV

 Update your CV before filling out the CCV  The most recent version of the Canadian Common CV (CCV)

  • To submit a CV to an organization, including the FRQS, you need to use

the most recent version of the funding CCV (www.ccv-cvc.ca) and select the organization  If you’re using the CCV system for the first time, you need to register (PIN, e- mail, password, etc.)  Read ALL the information

  • (e.g., some organizations have specific requirements)
  • Fill out the CCV clearly and submit it (e.g., FRQS)

 For the FRQ: Submit with CV and APPENDICES containing detailed contributions

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SLIDE 150

CONCLUSION

Be proactive throughout your training – improving your CV Persevere

Good luck and thanks for your attention