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9/26/2018 UCSF TRANSPLANT 2018 – Pioneering Advances in Transplantation
Can bind to tacrolimus and cyclosporine resulting in lower levels. Recommend to space by 2 hours. Can mask the symptoms of c.diff. Rule out first.
- Nephrotoxic. Cases of Acute renal
failure with minimal use.
Common OTCs
9/26/2018 UCSF TRANSPLANT 2018 – Pioneering Advances in Transplantation 9/26/2018 UCSF TRANSPLANT 2018 – Pioneering Advances in Transplantation 9/26/2018 UCSF TRANSPLANT 2018 – Pioneering Advances in Transplantation
Nephrotoxicity from NSAIDs
9/26/2018 UCSF TRANSPLANT 2018 – Pioneering Advances in Transplantation
Common OTCs
Can lead to a serious infection known as the “brain- eating” amoeba and bacterial infections. Use only distilled, sterile or boiled water (within 24h). Directly stimulates alpha and beta receptors. Causing: vasocontriction, tachycardia, and increased BP. Increases risk of arrhythmias and hypertension. Urinary retention Acute phosphate nephropathy (APN) has been reported. Some cases have resulted in permanent HD. Risk factors->55 yo, preexisting renal dysfunction, bowl
- bstruction, other renally toxic meds.
9/26/2018 UCSF TRANSPLANT 2018 – Pioneering Advances in Transplantation 9/26/2018 UCSF TRANSPLANT 2018 – Pioneering Advances in Transplantation
Common OTCs
9/26/2018 UCSF TRANSPLANT 2018 – Pioneering Advances in Transplantation
Anticholinergic side effects: dry mouth, difficulty urinating, tachycardia. High doses can cause hallucinations and delirium. Contains salicylate….. Used to treat diarrhea. C.diff must be ruled out before it can be used to self-treat. Can increase risk of bleeding with anticoagulants, can bind to other meds like cipro. Herbal blend: Echinacea Lonicera,Forsythia, Schizonepeta, Ginger, Vitex Trifolia, Isatis.
