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Substance Use Disorder Detection Among Providers of Medical Inpatients Kristin Serowik, PhD Interprofessional Fellowship in Advanced Addiction Treatment VA Connecticut Healthcare System Do Not Disseminate Without Permission from the Author


  1. Substance Use Disorder Detection Among Providers of Medical Inpatients Kristin Serowik, PhD Interprofessional Fellowship in Advanced Addiction Treatment VA Connecticut Healthcare System Do Not Disseminate Without Permission from the Author

  2. Rates are higher than general population Poor medical outcomes Why is detection so Higher healthcare utilization and costs important for this Direct optimal medical treatment population? Referral for addiction treatment

  3. Provider detection Alcohol: 37%-64% Illicit Drugs: 11%-56.5% Nicotine: 65%

  4. Primary aims for the current study • Update provider detection rates • DSM-5 • Contemporary clinical issues (opioid epidemic, marijuana laws) • Examine the relationship between patient characteristics and detection rates • Explore detection during the current hospitalization

  5. Participants (1076) • Recruited during admission • 13 general medical units at a large teaching hospital • 18+ years of age • Problematic use of nicotine, alcohol, illicit drugs, or prescription medications in past 28 days • Expected length of stay of a minimum of 2-3 days • Larger study examined the effectiveness of 3 distinct implementation strategies to promote the use of motivational interviewing

  6. Measures • Substance use diagnoses (SUD) • MINI • Provider detection • Medical record review (admission, until discharge) • Age, race/ethnicity, education, gender • Demographics questionnaire • Severity of use • Addiction Severity Index • Heaviness of Smoking • Mental and physical health-related quality of life • SF-12 • Motivation • Motivation to Change Scale • Length of stay (LOS) • Medical record review

  7. Mean (SD) % N Range Age 46.0 (13.7) Race/ethnicity White 55.2% 594 Black 31.3% 337 Hispanic 12.6% 135 Other 1.0% 10 Male 54.5% 586 SUD (MINI) Patient Nicotine 73.8% 794 Alcohol 50.6% 544 Characteristics Cannabis 15.1% 163 Cocaine 12.2% 131 Opioid 13.2% 142 Other Drug 8.4% 90 Education 12.9 (2.3) LOS 7.0 (7.2) SF-12 Physical 41.5 (12.4) 0-100 SF-12 MH 35.8 (11.1) 0-100 Motivation 7.2 (2.7) 0-10 Heaviness of Smoking 2.3 (1.6) 1-6 ASI – Drugs 0.129 (0.131) 0-1 ASI – Alcohol 0.204 (0.294) 0-1

  8. 0.94 0.93 0.93 0.89 0.89 0.87 0.86 0.84 0.84 0.80 0.74 0.74 0.72 0.65 0.61 0.54 0.51 0.26 NICOTINE ALCOHOL CANNABIS COCAINE OPIOID OTHER DRUG sensitivity specificity accuracy

  9. N I C O T I N E U S E D I S O R D E R A L C O H O L U S E D I S O R D E R ( N = 5 4 4 ) C A N N A B I S U S E D I S O R D E R ( N = 1 6 1 ) I L L I C I T D R U G U S E D I S O R D E R ( N = 7 9 4 ) ( N = 3 7 7 ) OR p OR p OR p OR p (CI) (CI) (CI) (CI) 1.01 0.046 1.03 <0.001 1.00 0.682 0.99 0.190 Age (1.00, 1.02) (1.02, 1.04) (0.97, 1.02) (0.96, 1.01) Black 0.79 0.668 0.42 0.983 0.74 0.380 0.46 0.880 (0.56, 1.11) (0.29, 0.60) (0.36, 1.63) (0.25, 0.85) 1.04 0.532 0.27 0.183 0.79 0.507 0.50 0.969 Hispanic (0.63, 1.72) (0.14, 0.53) (0.30, 2.07) (0.21, 1.17) Other 0.71 0.756 0.27 0.510 2.37 0.466 0.25 0.527 (0.13, 3.95) (0.05, 1.51) (0.14, 39.82) (0.02, 4.08) 1.12 0.479 3.23 <0.001 1.16 0.675 1.24 0.448 Male (0.82, 1.53) (2.26, 4.62) (0.57, 2.37) (0.71, 2.18) Education 1.01 0.828 1.03 0.438 0.98 0.801 0.89 0.099 (0.94, 1.08) (0.96, 1.11) (0.82, 1.17) (0.78, 1.02) 1.00 0.809 1.01 0.203 1.00 0.815 1.03 0.036 SF-12 (0.99, 1.02) (1.00, 1.03) (0.97, 1.04) (1.00, 1.06) Physical SF-12 1.00 0.748 0.98 <0.001 1.00 0.714 1.00 0.341 (0.99, 1.02) (0.96, 0.99) (0.97, 1.02) (0.96, 1.01) MH Motivation 0.98 0.455 1.18 <0.001 1.20 0.009 1.05 0.363 (0.92, 1.04) (1.11, 1.27) (1.05, 1.38) (0.94, 1.17) 1.20 0.001 1.61 <0.001 1.25 0.100 1.38 0.003 Addiction (1.08, 1.33) (1.48-1.74) (0.96-1.62) (1.11-1.70) Severity LOS 1.03 0.055 1.02 0.146 1.03 0.543 1.08 0.020 (1.00, 1.06) (0.99, 1.04) (0.95, 1.11) (1.01, 1.15) # SUDs 0.97 0.674 0.96 0.597 1.10 0.538 1.37 0.017 (0.84,1.12) (0.82,1.12) (0.82,1.47) (1.06,1.78)

  10. NICOTINE USE DISORDER ALCOHOL USE DISORDER CANNABIS USE DISORDER COCAINE USE DISORDER OPIOID USE DISORDER detected at admission detecteced during hospital stay

  11. Summary of findings • Provider detection varies, depending on substance • Detection rates for nicotine and alcohol comparable to prior research • Improvement in illicit drug use detection (51-65% vs. 11-56%) • Low overall detection for cannabis use disorder • Severity was most consistently linked to improved detection • The majority of SUD was detected during hospital admission

  12. Clinical Implications Barriers still exist to inpatient provider detection • Prompt in EHR are helpful • Training, supervision, consultation • Increase confidence and comfort discussing substance use with patients Shifting views on detrimental effects of use • Legalization of marijuana • Opioid epidemic

  13. References • Gryczynski J, Schwartz RP, O'Grady KE, Restivo L, Mitchell SG, Jaffe JH. Understanding Patterns Of High-Cost Health Care Use Across Different Substance User Groups. Health Aff (Millwood). 2016;35(1):12-19. • Hearne R, Connolly A, Sheehan J. Alcohol abuse: prevalence and detection in a general hospital. Journal of the Royal Society of Medicine. 2002;95(2):84- 87. • Heatherton TF, Kozlowski LT, Frecker RC, Rickert W, Robinson J. Measuring the heaviness of smoking: using self-reported time to the first cigarette of the day and number of cigarettes smoked per day. British journal of addiction. 1989;84(7):791-799. • Holt SR, Ramos J, Harma M, et al. Physician detection of unhealthy substance use on inpatient teaching and hospitalist medical services. Am J Drug Alcohol Abuse. 2013;39(2):121-129. • Martino S, Zimbrean P, Forray A, et al. Implementing Motivational Interviewing for Substance Misuse on Medical Inpatient Units: a Randomized Controlled Trial. Journal of general internal medicine. 2019;34(11):2520-2529. • Martins SS, Sarvet A, Santaella-Tenorio J, Saha T, Grant BF, Hasin DS. Changes in US Lifetime Heroin Use and Heroin Use Disorder: Prevalence From the 2001-2002 to 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions. JAMA Psychiatry. 2017;74(5):445-455. • McLellan AT, Kushner H, Metzger D, et al. The Fifth Edition of the Addiction Severity Index. J Subst Abuse Treat. 1992;9(3):199-213. • Miller WR, Johnson WR. A natural language screening measure for motivation to change. Addict Behav. 2008;33(9):1177-1182. • Monte AA, Zane RD, Heard KJ. The implications of marijuana legalization in Colorado. JAMA. 2015;313(3):241-242. • Priester MA, Browne T, Iachini A, Clone S, DeHart D, Seay KD. Treatment Access Barriers and Disparities Among Individuals with Co-Occurring Mental Health and Substance Use Disorders: An Integrative Literature Review. J Subst Abuse Treat. 2016;61:47-59. • Rudd RA, Seth P, David F, Scholl L. Increases in Drug and Opioid-Involved Overdose Deaths - United States, 2010-2015. MMWR. Morbidity and mortality weekly report. 2016;65(50-51):1445-1452. • Rumpf HJ, Bohlmann J, Hill A, Hapke U, John U. Physicians' low detection rates of alcohol dependence or abuse: a matter of methodological shortcomings? Gen Hosp Psychiatry. 2001;23(3):133-137. • Saitz R, Freedner N, Palfai TP, Horton NJ, Samet JH. The severity of unhealthy alcohol use in hospitalized medical patients. The spectrum is narrow. J Gen Intern Med. 2006;21(4):381-385. • Sheehan DV, Lecrubier Y, Sheehan KH, et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59 Suppl 20:22-33;quiz 34-57. • Shourie S, Conigrave KM, Proude EM, Haber PS. Detection of and intervention for excessive alcohol and tobacco use among adult hospital in-patients. Drug Alcohol Rev. 2007;26(2):127-133. • Smothers BA, Yahr HT. Alcohol use disorder and illicit drug use in admissions to general hospitals in the United States. Am J Addict. 2005;14(3):256-267. • Ware J, Jr., Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34(3):220-233.

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