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Post Post-Graduate Graduate Co Course urse in in Cl Clinical inical Ps Psychoneur ychoneuroimmunol oimmunology ogy CNELM Webinar | Leo Pruimboom Contents Contents Introductions: CNELM & Natura Foundation What is

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CNELM Webinar | Leo Pruimboom

Post Post-Graduate Graduate Co Course urse in in Cl Clinical inical Ps Psychoneur ychoneuroimmunol

  • immunology
  • gy
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Contents Contents

  • Introductions: CNELM & Natura Foundation
  • What is clinical psychoneuroimmunology (cPNI)?
  • Clinical PNI in practice
  • Practical course information
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About About Natura Foundation

  • Unique and leading international knowledge centre
  • Originator of clinical PNI
  • Extensive knowledge base and professional network
  • Local presence in UK, NL, ES, DE, AT, CH & TR
  • 6 highly rated courses
  • Over 16 years of experience
  • Educated over 10.000 successful health professionals
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Shared interest: our

clients

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More control of health for

everyone

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William, Health Professional

18-2-2015

What at does es he see see in n his s daily ily practi actice?

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What What does Wi William see see?

He sees an increasing number of clients who:

  • present with a complex combination of complaints
  • are dissatisfied with earlier treatments
  • desire more than a simple treatment of their symptoms

In short: Clients who are looking for more control of health

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How does Natura Foundation

help?

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  • Unique and integrative approach
  • Focuses on interactions between the brain, metabolism & immune system
  • Directly treating the cause, not the symptoms

The The solution: solution: Clinical Clinical PNI PNI

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CPNI CPNI and and its its metamodels metamodels

  • The Film
  • The Five Components
  • Energy Distribution
  • Transgenerational effects
  • The possible conflict between text and context
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Chronic disease

Immune component Low-grade inflammation Epigenetic programming

Disposable Organ Hyperactivity Muscles Global Immune system Detoxifying Liver Gluconeogenesis Memory Brain Breath Selenium Kidneys Sodium Gene repair Cells Insulin production Bones Vitamin K Coagulation

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Multiple sclerosis Th1 and Th17

Antibodies against myelin- based protein and MOG. Influenza A virus, EBV, herpes simplex virus, adenovirus, and Pseudomonas aeruginosa Porphyromonas gingivalis = smoking

Maturation of APC cells

Deficiencies: Vitamin D, Mg, Se, I, Omega-3 Chronic life stress Bisphenol Hypercitrullinated MBP

Low-grade inflammation

Prolactin >> Estrogens >> Cortisol deficiency Insulin resistance Glutamine/Leucin

PPIR Endotoxemia

Chronic activation Sympathetic Nervous System + HPA SNP Epigenetic programming

Early life stress

Early contact with gluten, casein, CLS, antibiotics

Non-healed wound

Disturbed Biorhythm

Omega-3 deficiency Pregnancy Women:men 4 : 1 Red meat/Milk Neu5Gc

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13

The The first st question tion = = epidemiology demiology

Multiple sclerosis Women : Men = 2.3 – 3.5 : 1

  • Harbo. Ther Adv Neurol Disord. (2013) 6(4) 237 - 248

First Conclusion:

  • Progesteron deficiency
  • Estrogens
  • Cortisol deficiency
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Allium sativum Resveratrol Curcuma

  • Balunas. Anticancer Agents Med Chem . 2008 August ; 8(6): 646–682.
  • Mobasheri. Int. J. Mol. Sci. 2012, 13, 4202-4232

Stress management

Quick k win win

  • Aromatase inhibitors
  • Cortisol-like substances
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Multiple sclerosis Th1 and Th17

Antibodies against myelin- based protein and MOG. Influenza A virus, EBV, herpes simplex virus, adenovirus, and Pseudomonas aeruginosa Porphyromonas gingivalis = smoking

Maturation of APC cells

Deficiencies: Vitamin D, Mg, Se, I, Omega-3 Chronic life stress Bisphenol Hypercitrullinated MBP

Low-grade inflammation

Prolactin >> Estrogens >> Cortisol deficiency Insulin resistance Glutamine/Leucin

PPIR Endotoxemia

Chronic activation Sympathetic Nervous System + HPA SNP Epigenetic programming

Early life stress

Early contact with gluten, casein, CLS, antibiotics

Non-healed wound

Disturbed Biorhythm

Omega-3 deficiency Pregnancy Women:men 4 : 1 Red meat/Milk Neu5Gc

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The The second nd questio tion = M MS and its substrate trate? ?

Antibodies against citrullinated myelin-based protein Second Conclusion: Smoking and Porphyromonas Gingivalis are risk factors

  • Z. Baka et al. / Joint Bone Spine 79 (2012) 431–436
  • Teanpaisan. Letters in Applied Microbiology 53, 452–459 ª 2011
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Multiple sclerosis Th1 and Th17

Antibodies against myelin- based protein and MOG. Influenza A virus, EBV, herpes simplex virus, adenovirus, and Pseudomonas aeruginosa Porphyromonas gingivalis = smoking

Maturation of APC cells

Deficiencies: Vitamin D, Mg, Se, I, Omega-3 Chronic life stress Bisphenol Hypercitrullinated MBP

Low-grade inflammation

Prolactin >> Estrogens >> Cortisol deficiency Insulin resistance Glutamine/Leucin

PPIR Endotoxemia

Chronic activation Sympathetic Nervous System + HPA SNP Epigenetic programming

Early life stress

Early contact with gluten, casein, CLS, antibiotics

Non-healed wound

Disturbed Biorhythm

Omega-3 deficiency Pregnancy Women:men 4 : 1 Red meat/Milk Neu5Gc

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Mimicry factors for MS:

  • Influenza A virus
  • EBV
  • herpes simplex virus
  • Adenovirus
  • Pseudomonas aeruginosa

But without Neu5Gc we would not lose our protection. The most important risk factors: Red meat and milk products

  • Samraj. 542–547 | PNAS | January 13, 2015 | vol. 112 | no. 2
  • Soulillou. Medical Hypotheses 80 (2013) 509–516

The The third third question question

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Context Context

Text

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Picture ture these e (highly ghly) ) stressful essful situations uations

  • A CEO with three kids: his or her partner dies
  • A housewife and natural mother: her children emigrate to Australia
  • A naturopath working in a conventional hospital
  • A biopsychiatrist with a depressed partner taking prozac
  • A child losing his or her parents
  • Yourself in an impossible environment
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Physiological Emotional Social Cognitive Sexual

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Physiological

  • Insulin resistance = exercise/meal frequency/bitter melon/metformin

Emotional

  • I am afraid that it will never go away

Cognitive

  • I do not have any solutions

Social

  • If I would be cured, my parents would probably ask for a divorce

Sexual

  • I am infertile and only 23 years old

Physiol iologi

  • gical

cal/Emot Emotiona ional/Co Cognit gnitive ive/Soci Socia l/Sexual xual

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Disposable Organ Hyperactivity

Muscles Global Immune system Detoxifying Liver Gluconeogenesis Memory Brain Breath Selenium Kidneys Sodium Gene repair Cells Insulin production Bones Vitamin K Coagulation

Energy distribution is the first step in every treatment plan

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Benefits!

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You You will will…

… be better able to help your patients regain control of their health … develop yourself into a broader and even more competent health professional … be able to make a difference, which confers to you a clear competitive advantage … be able to apply what you have learnt in your own (family) life … become part of an innovative and fast-growing community

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The The bottom bottom line line

  • Improve your professional reputation
  • Enhance your success
  • Be more satisfied with your work
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The training programme is:

  • Pragmatic, interactive and challenging
  • Based on the latest scientific developments

Our lecturers:

  • Have extensive practical experience
  • Are consistently inspiring

Our study material is:

  • Based on recent scientific research and practical experience

Duration

  • 36 days spread over 2 years, 560 clock hours in total
  • Study hours from 9.00 a.m. until 5.30 p.m.

Practical Practical informatio information

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Course Dates cPNI 1:

  • Days 1-3: Sun 26th – Tues 28th April 2015
  • Days 4-6: Mon 8th – Wed 10th June 2015
  • Days 7-10: Sat 11th – Tues 14th July 2015
  • Days 11-12: Mon 7th – Tues 8th September 2015
  • Days 13-15: Mon 19th – Wed 21st October 2015
  • Days 16-18: Fri 4th – Sun 6th December 2015

Course Fees:

  • Standard fee: £2390 + exam fee (optional)
  • Online access to lecture content only: £2140 + £350 for 1

week intensive + exam fee (optional)

  • Refresher Fee for existing cPNI Therapists: £1195 (or £70

per day attending and/or online)

Book Your Place:

  • Download Registration Form at:

http://cnelm.co.uk/courses/cpni/

Practical Practical informatio information

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Any Any questions questions?