Part the Cloud Awardees Funding 50 1 Michael Weiner PTC - - PowerPoint PPT Presentation

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Part the Cloud Awardees Funding 50 1 Michael Weiner PTC - - PowerPoint PPT Presentation

Part the Cloud Awardees Funding 50 1 Michael Weiner PTC Foundations Private 2 Anne Longo 40 3 Adam Boxer 4 Dale Bredesen Venture/ Indirect 5 Keith Vossel 30 GOV Corporate Funding* 6 Ahmad Salehi 7 Stephen Cunnane 20 8


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Millions ($) Part the Cloud Investigator by Year Awarded

PTC GOV Foundations Venture/ Corporate

2013 2015 2016

Private Indirect Funding*

* government, foundation,

corporate/ venture capital and individual support that is indirectly related to the Part the Cloud Translational award.

2017

1 Michael Weiner 2 Anne Longo 3 Adam Boxer 4 Dale Bredesen 5 Keith Vossel 6 Ahmad Salehi 7 Stephen Cunnane 8 Whitney Wharton 9 Giulio Pasinetti 10 Tim West 11 Russell Swerdlow 12 Paul A. Newhouse 13 Mitchel Kling 14 Joseph Foss 15 Isidro Ferrer 16 John Olichney 17 Anthony Oliva 18 Huntington Potter 19 Franz Hefti 20 Linda Van Eldik 21 Mark Tuszynski 22 Krista Lanctot 23 Manfred Windisch

50 40 30 20 10 4 5 3 2 1 1 3 5 7 9 11 13 15 17 19 21 23

Part the Cloud Awardees – Funding

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Preclinical Phase 1 Phase 2

TPI-287 F03* Perindopril BDPP Treatment Oxaloacetate PPI-1011 SCCF-3012 NPT088 NTRX-07 MW189 BDNF Mesenchymal Stem Cells VU0467319 PTC Investment to Phase 1 LM11A-31-BHS C2N-8E12 (ABBV-8E12)

PTC Investment to Phase 1; Additional $ to Phase 2

Levetiracetam Formoterol* Senicapoc GM-CSF Sativex

PTC Clinical Pipeline

* Studies not continued due to recruitment challenges.

PTC Investment to Phase 2 N-acetylsysteine (NAC) MW150

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Global Reach

Over 100 Researchers in 13 Countries Provide Expert Review

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SLIDE 4

Global Reach

Evaluated Over 400 Clinical Studies from 26 Countries

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SLIDE 5

Global Reach

Advancing Over 20 Clinical Trials Around the World