MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry - - PowerPoint PPT Presentation

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MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry - - PowerPoint PPT Presentation

MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry Fragrances & Fine Chemistry Co diploma Co diploma MASTER 2 Chemistry MASTER 2 Chemistry Nice Nice Grasse Nice Grasse MASTER 2 Research MASTER 2 Research


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MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry Fragrances & Fine Chemistry

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Nice

Co diploma Co diploma MASTER 2 Chemistry MASTER 2 Chemistry

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Nice

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Nice

Grasse

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Grasse

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1 1st

st Semester

Semester

October October-

  • December

December

MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry Fragrances & Fine Chemistry

Organic synthesis Organic synthesis Fragrance Fragrance Chemistry Chemistry Analytical Analytical chemistry chemistry Bibliography Bibliography & Project & Project management management

English courses English courses

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1 1st

st Semester

Semester

October October-

  • December

December

MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry Fragrances & Fine Chemistry

Organic synthesis Organic synthesis Fragrance Fragrance Chemistry Chemistry Analytical Analytical chemistry chemistry Bibliography Bibliography & Project & Project management management

English courses English courses

2 2nd

nd Semester

Semester

January January-

  • June

June

Practical activity

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http://www.unice.fr/ecomers/ http://www.unice.fr/ecomers/

Host laboratories Host laboratories

http://www.unice.fr/icn/ http://www.unice.fr/icn/ http://lpmc.unice.fr/ http://lpmc.unice.fr/

Laboratoire Physique de la Matière Condensée

http://www.cepam.cnrs.fr/ http://www.cepam.cnrs.fr/

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http://www.unice.fr/icn/ http://www.unice.fr/icn/

Bioactive molecules

Marine Natural Products

Fluorescent Probes Decorporation

Eco-Friendly Materials and Polymers

Bioinspiration

Catalysis & Fine Chemistry

Fragrance chemistry Origin of Life

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Bioactive molecules

Natural Synthetic

RNA Proteins

Induce stress in cancer cells Selective targeting of cancer stem cells

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Marine Natural Products

Applications:

  • Pharmaceutical
  • Environmental (antifoulings)
  • Cosmetics
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Marine Natural Products

Applications:

  • Pharmaceutical
  • Environmental (antifoulings)
  • Cosmetics

Isolation Isolation Metabolome Metabolome Structural determination Structural determination Synthesis Synthesis Valorization Valorization

Extraction Extraction

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Fluorescent Probes

Objective To understand nucleic acid / protein and nucleic acid / nucleic acid assemblies. How ? Synthesis of dedicated fluorescent tools for in vitro studies and cell imaging

Internal Labeling ε ≈ 18,000 M-1.cm-1 Ф ≈ up to 38 %

O O O P O O O O HO S

370 nm

440 nm 540 nm

Br Br N Br R2 R1

Pd-catalyzed monoamination

[12 examples] [air-stable cat. syst.] [practical & gram-scale] [varied-amine tolerance]

N R2 R1 O

Acceptor Functionalization

R1,R2 = H, aryl & aliphatic

Clickable Bioconjugation

Applications

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Decorporation

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Eco-Friendly Materials and Polymers

*Biobased and/or eco-friendly polymers and (nano)composites *Valorization of :

  • second generation biomass
  • co-products from industry and bioraffineries

*Recycling and circular economy

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Eco-Friendly Materials and Polymers

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Bioinspiration

Inspiration from natural surfaces (Animal and vegetal) Applications for Surface Elaboration :

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Chemistry Electropolymerization Surface characterizations

Bioinspiration

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Catalysis & Fine Chemistry

M A + B A B Sustainable development Development of selective methods: C-C, C-O, C-N, C-F… High production, optimization of process

Recyclable catalyst Water-soluble catalyst Chiral catalyst

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Catalysis & Fine Chemistry

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Fragrance chemistry

O

Mimosa Violet Atlas Cedarwood Vetiver Frankincense Characterisation of the odorants of natural raw materials : Chemical and Sensorial Analysis of Volatiles

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Fragrance chemistry

Characterisation of pheromones : Chemical Analysis & Behavioral studies Murine model : Human model :

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Origin of Life

Myrgorodska, Meinert, Meierhenrich et al.: Angew. Chem. Int. Ed. 54 (2015), 1402

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MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry Fragrances & Fine Chemistry

CONTACT : CONTACT : baldovin@unice.fr baldovin@unice.fr