MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry - - PowerPoint PPT Presentation
MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry - - PowerPoint PPT Presentation
MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry Fragrances & Fine Chemistry Co diploma Co diploma MASTER 2 Chemistry MASTER 2 Chemistry Nice Nice Grasse Nice Grasse MASTER 2 Research MASTER 2 Research
Nice
Co diploma Co diploma MASTER 2 Chemistry MASTER 2 Chemistry
Nice
Nice
Grasse
Grasse
1 1st
st Semester
Semester
October October-
- December
December
MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry Fragrances & Fine Chemistry
Organic synthesis Organic synthesis Fragrance Fragrance Chemistry Chemistry Analytical Analytical chemistry chemistry Bibliography Bibliography & Project & Project management management
English courses English courses
1 1st
st Semester
Semester
October October-
- December
December
MASTER 2 Research MASTER 2 Research Fragrances & Fine Chemistry Fragrances & Fine Chemistry
Organic synthesis Organic synthesis Fragrance Fragrance Chemistry Chemistry Analytical Analytical chemistry chemistry Bibliography Bibliography & Project & Project management management
English courses English courses
2 2nd
nd Semester
Semester
January January-
- June
June
Practical activity
http://www.unice.fr/ecomers/ http://www.unice.fr/ecomers/
Host laboratories Host laboratories
http://www.unice.fr/icn/ http://www.unice.fr/icn/ http://lpmc.unice.fr/ http://lpmc.unice.fr/
Laboratoire Physique de la Matière Condensée
http://www.cepam.cnrs.fr/ http://www.cepam.cnrs.fr/
http://www.unice.fr/icn/ http://www.unice.fr/icn/
Bioactive molecules
Marine Natural Products
Fluorescent Probes Decorporation
Eco-Friendly Materials and Polymers
Bioinspiration
Catalysis & Fine Chemistry
Fragrance chemistry Origin of Life
Bioactive molecules
Natural Synthetic
RNA Proteins
Induce stress in cancer cells Selective targeting of cancer stem cells
Marine Natural Products
Applications:
- Pharmaceutical
- Environmental (antifoulings)
- Cosmetics
Marine Natural Products
Applications:
- Pharmaceutical
- Environmental (antifoulings)
- Cosmetics
Isolation Isolation Metabolome Metabolome Structural determination Structural determination Synthesis Synthesis Valorization Valorization
Extraction Extraction
Fluorescent Probes
Objective To understand nucleic acid / protein and nucleic acid / nucleic acid assemblies. How ? Synthesis of dedicated fluorescent tools for in vitro studies and cell imaging
Internal Labeling ε ≈ 18,000 M-1.cm-1 Ф ≈ up to 38 %
O O O P O O O O HO S
370 nm
440 nm 540 nm
Br Br N Br R2 R1
Pd-catalyzed monoamination
[12 examples] [air-stable cat. syst.] [practical & gram-scale] [varied-amine tolerance]
N R2 R1 O
Acceptor Functionalization
R1,R2 = H, aryl & aliphatic
Clickable Bioconjugation
Applications
Decorporation
Eco-Friendly Materials and Polymers
*Biobased and/or eco-friendly polymers and (nano)composites *Valorization of :
- second generation biomass
- co-products from industry and bioraffineries
*Recycling and circular economy
Eco-Friendly Materials and Polymers
Bioinspiration
Inspiration from natural surfaces (Animal and vegetal) Applications for Surface Elaboration :
Chemistry Electropolymerization Surface characterizations
Bioinspiration
Catalysis & Fine Chemistry
M A + B A B Sustainable development Development of selective methods: C-C, C-O, C-N, C-F… High production, optimization of process
Recyclable catalyst Water-soluble catalyst Chiral catalyst
Catalysis & Fine Chemistry
Fragrance chemistry
O
Mimosa Violet Atlas Cedarwood Vetiver Frankincense Characterisation of the odorants of natural raw materials : Chemical and Sensorial Analysis of Volatiles
Fragrance chemistry
Characterisation of pheromones : Chemical Analysis & Behavioral studies Murine model : Human model :
Origin of Life
Myrgorodska, Meinert, Meierhenrich et al.: Angew. Chem. Int. Ed. 54 (2015), 1402