If ever a field needed remodelling, it is medicine N EW ERA IN MUTI - - PowerPoint PPT Presentation

if ever a field needed remodelling it is medicine
SMART_READER_LITE
LIVE PREVIEW

If ever a field needed remodelling, it is medicine N EW ERA IN MUTI - - PowerPoint PPT Presentation

Mahidol Mah Univ University Wisdom of the Land If ever a field needed remodelling, it is medicine N EW ERA IN MUTI - DISCIPLINARY RESEARCH : B IOMEDICAL ENGINEERING I NNOVATIVE STRATEGIES Chumpon Wilasrusmee Department of Surgery,


slide-1
SLIDE 1

NEW ERA IN MUTI-DISCIPLINARY

RESEARCH:

BIOMEDICAL ENGINEERING INNOVATIVE STRATEGIES

Chumpon Wilasrusmee Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok

“If ever a field needed remodelling, it is medicine”

Mah Mahidol

Univ University

Wisdom of the Land

slide-2
SLIDE 2

Improve patient care Improve patient-physician relationship Eliminate potential errors Is it true: Chaotic, inefficient, and often ineffective, health care

is dying for innovation

มีก็ไมใช

Standard

Diffusion and resistance

AIM - SCIENTIFIC PAPER

  • INNOVATION
slide-3
SLIDE 3

Application of new solutions that meet new requirements,

needs

More effective products, processes, services, technologies, or

ideas

Original and new that "breaks in to" the market or into

society

Important in some way Process that brings together various novel ideas in a way

that they have an impact on society

Differs from invention: use of a better Invention: creation of idea or method itself Differs from improvement doing something different rather than doing the same thing better.

WHAT IS??

slide-4
SLIDE 4

Rank Country Overall Innovation Inputs Innovation Performance 2 United States 1.80 1.28 2.16 3 Japan 1.79 1.16 2.25 4 Sweden 1.64 1.25 1.88 5 Netherlands 1.55 1.40 1.55 6 Canada 1.42 1.39 1.32 7 United Kingdom 1.42 1.33 1.37 8 Germany 1.12 1.05 1.09 9 France 1.12 1.17 0.96 10 Australia 1.02 0.89 1.05 11 Spain 0.93 0.83 0.95 12 Belgium 0.86 0.85 0.79 13 China 0.73 0.07 1.32 14 Italy 0.21 0.16 0.24 15 India 0.06 0.14 −0.02 16 Russia −0.09 −0.02 −0.16 17 Mexico −0.16 0.11 −0.42 18 Turkey −0.21 0.15 −0.55 19 Indonesia −0.57 −0.63 −0.46

ปจจุบันประเทศไทยมีงานวิจัยและสิ่งประดิษฐที่มี ศักยภาพจํานวนมากที่ยังไมไดถูกเปดเผยและไมได ถูกนํามาใชงานอยางแพรหลาย เนื่องจากที่ผาน มายังขาดการพัฒนาตอยอดหรือขยายผลไปสู ผลงานในเชิงนวัตกรรม ดังจะเห็นไดจากผลการจัด อันดับความสามารถดานนวัตกรรมในป พ.ศ. 2554-2555 ของ World Economic Forum พบวา ประเทศไทยอยูในอันดับที่ 51 รองจากประเทศเพื่อนบานในภูมิภาคอาเซียนถึง 3 ประเทศ ไดแก มาเลเซีย สิงคโปร อินโดนีเซีย

slide-5
SLIDE 5

Core mission Core value Future of organization

Laparoscopic versus conventional appendectomy in suspected appendicitis during pregnancy: A systematic review and meta-analysis

  • British Journal of Surgery 2012

BIOMEDICAL ENGINEERING: INNOVATIVE STRATEGY

slide-6
SLIDE 6
  • Sir,
  • Congratulations on an excellent analysis, which seems to be the largest systemic review of

appendectomy for suspected appendicitis in pregnancy. However, I have several comments.

  • Thank you for your comment in our publication” Systematic review and meta-analysis of safety of laparoscopic versus
  • pen appendicectomy for suspected appendicitis in pregnancy” We hope that these answers will give additional

information regarding our analysis.

First, laparoscopy has the benefit of identifying other intra-abdominal

pathology which may mimic appendicitis and harbor pregnancy risks. Besides, pelvic toileting could be performed more safely under the vision of

  • laparoscopy. Irrigation and suction of pelvic fluid could lower the risk of

possible abscess formation, uterus irritation and further fetal loss.

  • We truly agree with the technical advantage of laparoscopic appendectomy (LA). Recent publication by Khiria, et al

also showed the safety of LA in complicated appendicitis (Ref1). However, evidence from Cochrane data base showed that the incidence of intraabdominal abscesses was increased (OR 1.87; CI 1.19 to 2.93) and the duration of surgery was 10 minutes (CI 6 to 15) longer for LA (ref2)

Second, laparoscopic approach could lessen and avoid unexpected wound

extension, compared with McBurney's incision due to migration of appendix in the pregnant. Thus, post-operative wound pain and associated pulmonary complication could be decreased when using laparoscopic approach.

AFTER PUBLICATION

slide-7
SLIDE 7

the moment; references are of 1990 and 1995; 2- performance of the CT scan are very high and low resolution CT scan and/or IRM have the same sensibility and specificity to diagnose appendicitis; 3- recent works on epidemiology of appendicitis demonstrated that there are two forms of appendicitis, with no relation together: uncomplicated and complicated, so negative laparotomy or laparoscopy must not be any more performed; patients can be se one day later if any doubt subsist.

all the paper must be rewritten

REVIEWER COMMENTS

slide-8
SLIDE 8

Andrease Vesalius: human anatomy-hand on

dissection

James Lind: Scurvy – lemon, vitamin C Edward Jerner: smallpox Group of people who continue developing

innovation to optimum or best practice

INNOVATION-FIGHTING DISEASE

slide-9
SLIDE 9

External: outside influence of control Internal: within the control Associated with the cultural infrastructure Associated with the innovation process itself:

  • Poor goal definition
  • Poor alignment of actions to goals
  • Poor participation in teams
  • Poor monitoring of results
  • Poor communication and access

to information

FAILURE

slide-10
SLIDE 10
  • Difference screening tests result

in different detection prevalence of diabetic neuropathy even in the same group of patients

  • The RMI could be used as a

reliable tool in the screening of diabetic neuropathy.

Robotic monofilament inspector

slide-11
SLIDE 11

COMPARISON OF RECEIVER OPERATING CHARACTERISTIC

CURVES OF RMI, SW, VP, AND TC FOR THE DETECTION OF DIABETIC NEUROPATHY

slide-12
SLIDE 12

Mah Mahidol

Univ University

Wisdom of the Land

RMI Model I, II, III

slide-13
SLIDE 13

Encourage the continuous development Increase in value Providing a much greater health benefit or wider

societal benefits

Patency: Set of exclusive rights granted by a state (national

government) to an inventor or their assignee for a limited period of time in exchange for the public disclosure of an invention

Gateway

PROMOTING INNOVATION

slide-14
SLIDE 14
slide-15
SLIDE 15

NOTE: Weights are from random effects analysis Overall (I-squared = 30.7%, p = 0.194) Enzler (1996) Wang (1996) Bacchini (2001) Eikhoff (1987) McCollum (1991) Study ID Eikhoff (1983) Koch (1996) 1.31 (1.12, 1.54) 1.23 (0.95, 1.59) 1.38 (0.76, 2.51) 1.56 (0.66, 3.72) 1.89 (1.04, 3.43) 1.20 (0.91, 1.56) RR (95% CI) 1.87 (1.30, 2.67) 1.09 (0.87, 1.35) 100.00 22.03 6.39 3.27 6.47 21.01 % Weight 14.60 26.24 1.31 (1.12, 1.54) 1.23 (0.95, 1.59) 1.38 (0.76, 2.51) 1.56 (0.66, 3.72) 1.89 (1.04, 3.43) 1.20 (0.91, 1.56) RR (95% CI) 1.87 (1.30, 2.67) 1.09 (0.87, 1.35) 100.00 22.03 6.39 3.27 6.47 21.01 % Weight 14.60 26.24 1 .2 .4 .5 .7 1 1.3 2

META-ANALYSIS

slide-16
SLIDE 16

This was a first systematic review and meta-

analysis of studies comparing BP and PTFE in peripheral vascular reconstruction

Our first meta-analysis indicated that the

biosynthetic prosthesis might be benefit over PTFE by increasing graft patency

An updated meta-analysis or a large scale

randomized control trial is required to confirm this benefit

BIOGRAFT

slide-17
SLIDE 17

Intelligent interpretation of x-ray images Computer axial tomography scans, ultrasound images and other sensor

data

Medical data mining; medical informatics; smart patient record systems Medical sensors and sensor systems; wired and wireless sensor networks;

smart monitoring and reporting

Expert and case-based reasoning systems for medical diagnosis and

decision support in medicine and healthcare

Robotics surgical and micro-surgical systems; robotic surgical assistants Robotic artificial joints and joint assistance systems Integrated medical systems to assist in delivering quality health care

during spaceflight and exploration

The use of smart systems to to alleviate problems in the aging population Smart medical devices Neural networks, fuzzy paradigms, genetic algorithms, expert systems in

medical and healthcare applications

RECENT INTERESTING FIELD

slide-18
SLIDE 18

Dominated by cosmetic component: not cover by

insurance

Poor concerning, education, and prevention of

ergonomic

Thesis: Faculty of Health Sciences

DIFFERENCE:

VARICOSE VEINS: MYTH: WORKING ASSOCIATED DISEASE?

slide-19
SLIDE 19

Figure 1 : Severity classification of chronic venous disease

NURSE VS FACTORY EMPLOYEE

slide-20
SLIDE 20

OBJECT TRACKING FOR LAPAROSCOPIC SURGERY USING THE ADAPTIVE MEAN-SHIFT KALMAN ALGORITHM

slide-21
SLIDE 21

MULTI-DISCIPLINARY

slide-22
SLIDE 22

Vixol - gastric outlet obstruction

CASE REPORT

slide-23
SLIDE 23

VIRTUAL REALITY SURGICAL TRAINING SYSTEM

slide-24
SLIDE 24

REGISTRATION BEFORE PUBLICATION: RCT ETHICAL CONSIDERATION

slide-25
SLIDE 25

BIOMEDICAL-MULTIDISCIPLINARY-INNOVATION

I-nversion N-ew N-eed O-bsess V-isibility A-mbition T-alent I-ntegration O-bvious N-iche, network

slide-26
SLIDE 26

ENDOTHELIAL INJURY

I-Inversion

slide-27
SLIDE 27

IN VITRO TO IN VIVO

slide-28
SLIDE 28

VASCULAR ANASTOMOSIS MODEL

N-New

รามาธิบดีควารางวัลสภาวิจัยแหงชาติ : ผลงานประดิษฐคิดคนประจําป 2550 รองศาสตราจารยจุมพล วิลาศรัศมี อาจารยประจําภาควิชาศัลยศาสตร คณะ แพทยศาสตรโรงพยาบาลรามาธิบดี มหาวิทยาลัยมหิดล เปนหนึ่งในผูที่ไดรับรางวัล สภาวิจัยแหงชาติ : รางวัลผลงานประดิษฐคิดคน ประจําป 2550 จากผลงาน แบบจําลอง ฝกหัดตัดตอหลอดเลือด

slide-29
SLIDE 29

BENCH TO CLINIC

N-Need

slide-30
SLIDE 30

AAA MODEL

O-obsess

slide-31
SLIDE 31

MESH

V-visibility

slide-32
SLIDE 32
  • 4. ผลงานเรื่อง “Mesh Plug ที่ตัดเย็บขึ้นเองสาหรับการผาตัดรักษาไสเลื่อน” โดย

รองศาสตราจารย เรือโทจุมพล วิลาศรัศมี นางกุลณิช จิรัชยาพร นางสาวนทีชา ปนยะกุล นางสาวอรพันธ พรรณประดิษฐ นางสาวนิณัฐนันท พรมโสภา (สาขาวิทยาศาสตรการแพทย)

A-ambition

slide-33
SLIDE 33

ROBOT

T-talent

slide-34
SLIDE 34

I-INTEGRATION

slide-35
SLIDE 35
slide-36
SLIDE 36

HOT

“ The beautiful is a phenomenon which is never apparent of itself, but is reflected in a thousand different works of the creator. ” — Johann Wolfgang von Goethe

O-obvious

slide-37
SLIDE 37

N-NICHE, NETWORK

slide-38
SLIDE 38

Perioperative steroids have a favourable impact on

postoperative outcomes after liver resection

Intravenous glucocorticoids were 24 per cent less likely to

suffer postoperative morbidity compared with controls (risk ratio 0.76, 95 %CI 0.57 to 0.99; P = 0.047)

The treated group experienced a significantly greater rise in

early postoperative interleukin (IL) 10 levels compared with controls

In addition, steroids significantly reduced postoperative blood

levels of bilirubin, and of inflammatory markers such as IL-6 and C-reactive protein

There was no evidence supporting a risk difference in infectious

complications and wound healing between study groups.

BR J SURG. 2013 APR;100(5):600-9EPUB 2013 JAN 21. SYSTEMATIC REVIEW AND META-ANALYSIS OF THE EFFECT OF PERIOPERATIVE STEROIDS ON

ISCHAEMIA-REPERFUSION INJURY AND SURGICAL STRESS RESPONSE IN PATIENTS UNDERGOING LIVER RESECTION

RE-INNOVATION

slide-39
SLIDE 39

POSITIVE THINKING

New medications, new diagnostic techniques, and

new surgical procedures helped millions of patients not only to live longer, but also to possess better-quality lives.

Change is necessary because our society needs

the next generation

New knowledge plus existing knowledge adapted

and diffused through the economy Effort and courage are not enough without purpose and direction