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Exploring the Risk Environment: Challenges and Opportunities in Reducing Harm among People who Inject Drugs Thomas Kerr, PhD Director, Urban Health Research Initiative, BC Centre for Excellence in HIV/AIDS, Professor, Department of Medicine,


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Exploring the Risk Environment: Challenges and Opportunities in Reducing Harm among People who Inject Drugs

Thomas Kerr, PhD

Director, Urban Health Research Initiative, BC Centre for Excellence in HIV/AIDS, Professor, Department of Medicine, University of British Columbia Associate Scientist, Ontario HIV Treatment Network

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Individual

Conventional Approaches

INTERVENTIONS

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Individual

Risk Environment Framework

INTERVENTIONS

Social

  • Local drug use patters
  • Peer group norm

Structural

  • Economic conditions
  • Laws & social policies

Environmental

  • Features of built

environment

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Policing

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Mitsampan Community Research Project

  • A collaborative research effort involving:
  • Serial cross-sectional

mix-methods study

  • 32 former/active drug users

trained as peer researchers

  • Peer researchers involved in

all stages of the project

Thai AIDS Treatment Action Group Mitsampan Harm Reduction Center Chulalongkorn University Summer 2008, Bangkok, Thailand

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10

PWID in Bangkok, 2011 (n=435) * Refers to the previous 6 months.

13% 14% 28% 45%

Ever beaten and drug tested* by police Drug tested* by police only Ever beaten by police only None of the two events

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11 Hayashi et al,. AIDS Behav, 2013

Policing exposures and syringe sharing

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12

  • 13% of PWID with negative or unknown HIV status

reporting avoiding HIV testing.

  • Increased police presence where one buys or uses

drugs was significantly associated with HIV test avoidance (OR: 2.06; 95% CI: 1.10–3.84).

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Fear, Displacement and Risk

Drug enforcement policing:

  • Fear and hurried injection
  • Syringe reuse, sharing, lending
  • Interruptions in service access due to displacement

These days they just take it and shoot it up right away. They don’t look at what they have got or think about how strong it may be. IDU Respondent #25. People are at a higher risk because they are being forced to go into areas that they don’t know. Usually there are no services provided in those areas where they can get clean works, or be observed or helped by someone. Service Provider Respondent # 8.

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Incarceration

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Journal of Infectious Diseases, 2011

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HAART & Incarceration

Factors influencing inmates’ ability to access and adhere to HAART: Short term interruptions in treatment during intake and transfers Delays in obtaining medications through institutional healthcare High levels of HIV discrimination and stigma Problems ensuring continuity of treatment post-release

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Changes in policies to :

  • Improve intake process
  • Reduce pharmacy-related delays
  • Ensure contingency supplies of medications
  • Provide sufficient medication at discharge
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Hospitals as ‘risk environments’ for people who use drugs?

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Leaving Hospital Against Medical Advice

  • September 2005 - July 2011: 488 PWUD hospitalized
  • 43% of PWUD left AMA
  • Younger patients, daily heroin injectors and those recently

incarcerated most likely to leave AMA

(Ti et al., PloS One, 2015)

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Why AMA?

  • Pain management, withdrawal, under-treated addiction
  • Social-structural conditions: abstinence-only policies,

security guards, lack of access to syringes

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I think they pretty much have zero tolerance in [the hospital]. I was worried about getting kicked out and then not getting the proper health care that I needed to get better. [.] I’d turn the tap on so, if they came in my room to check to see if I was okay, then they’d hear the water running so they’d figure oh she’s just in the bathroom. [Participant #25, Caucasian Female, 44 years old]

McNeil et al, Soc Sci Med, 2014)

Abstinence-only Policies

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[Security guards] yell and scream at you. When there’s nobody around, [they say], “You fucking junkie.”…They search you, destroy your property, cause a scene, and make sure everybody there knows that you’re a drug addict. [.] They use their authority to pull power trips more or less. It’s not

  • right. [Participant #12, Aboriginal Female, 29

years old]

(McNeil et al, Soc Sci Med, 2014)

Security Guards and Police

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Overdose Prevention

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Overdose prevention assumes rationality and personal autonomy, emphasizes the self- regulating subject

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Social-structural factors: extreme poverty, shifting quality and illegal status of heroin, risky income generating activities Individual factors: entrenched injecting routines, perceived invincibility, ambivalence towards death

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Micro-environmental Interventions?

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Willingness to use an in-hospital SIF

Common reasons:

  • So they could stay in

hospital

  • To reduce their drug-

related risks

  • To reduce stress about

being kicked out because they were using drugs

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Socio-economic marginalization

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Social Assistance in B.C.: Institutional Design

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  • Overall and high-risk drug and

alcohol use

  • Fatal and non-fatal overdose
  • Drug-related ED and hospital

admissions

  • Addiction and HIV treatment

interruption

  • Health, social and financial service

access barriers

  • Public disorder
  • Mental health apprehensions
  • Police service calls
  • Hospital discharge against

medical advice

Provincial Government Cheque Issue

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The impact of alternative social assistance disbursement on drug-related harm (TASA): a randomized controlled trial

PI: Lindsey Richardson, DPhil Assistant Professor, Department of Sociology, University of British Columbia Research Scientist, B.C. Centre for Excellence in HIV/AIDS

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Which social assistance disbursement schedule most effectively mitigates escalations in drug-related harm coinciding with government cheque issue?

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Richardson et al. (2016) BMC Public Health

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TASA: Changing payment timing and frequency

Social Assistance Payment

Shelter Allowance Support Allowance

Direct deposit

Staggered Arm Staggered & Split Arm

  • Payments released once per month on day

during the first two weeks of the month to avoid cheque issue week

  • Day randomly chosen after randomization
  • Gradual transition to new date to avoid

unacceptably long period between payments

  • Payments released twice per month, first on a

day during the week after cheque issue week, second two weeks later

  • Days randomly chosen after randomization

Gradual transition to new date to avoid unacceptably long period between payments

Direct to landlord

Control Arm

  • Once monthly payment on cheque day
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  • Prohibited income generation: sex work, drug dealing,

theft, squeegeeing, binning, panhandling

  • Among 687 HIV+ ART-exposed PWUD:

– 391 (57%) reported prohibited income generation – Prohibited income generation negatively associated with viral suppression (Adjusted Odds Ratio = 0.74, 95% Confidence Interval: 0.56 – 0.97)

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29% 37% 44% 63% 0% 10% 20% 30% 40% 50% 60% 70% Binning Panhandling Drug dealing Sex work

Willing to give‐up if had other employment op ons

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Structural Intervention: Low-Threshold Employment

Increasing low-threshold employment access

Aim:

  • To evaluate an intervention to

increase access to low-threshold jobs for PWUD Intervention:

  • A digital clearing house of task-based

work that PWUD undertake according to availability and preference Outcomes:

  • Employment, high-risk income

generation, drug use and related risk, clinical outcomes

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“…medical cannabis laws were associated with a 24.8% lower annual rate of opioid analgesic

  • verdose deaths.”

JAMA Internal Medicine, 2014

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Figure 1. Frequencies of crack cocaine (Panel A) and cannabis use (Panel B) in each of the intentional cannabis use periods. (Socias et al, under rev

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“Drugs have destroyed many people, but wrong policies have destroyed many more.”

Kofi Annan, former UN Secretary General

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Conclusions

  • Drug-related harm is shaped by the broader risk

environment

  • Individually-focused interventions are of limited impact
  • Opportunities to intervene at the social, structural and

environmental level exist

  • Implement

and evaluate alternative regulatory approaches

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Acknowledgements

  • The people who use drugs who participate in our research
  • Research staff
  • Co-investigators
  • Funders