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Electronic PRO Monitoring in Duke Oncology Clinics World Cancer Congress Presentation Bradford Hirsch, MD, MBA August 28 rd , 2012 Medicine at Transition Point Medicine at Transition Point Care Redesign Patient Quality Centered Data


  1. Electronic PRO Monitoring in Duke Oncology Clinics World Cancer Congress Presentation Bradford Hirsch, MD, MBA August 28 rd , 2012

  2. Medicine at Transition Point

  3. Medicine at Transition Point Care Redesign Patient Quality Centered Data Metrics Care Driven Care Personalized CER Medicine

  4. Evidence Based Medicine: A Paradigm Shift ! Concerted international effort to close the gap between research and practice (CER, PM … ) ! Systematic collection, synthesis, and use of evidence to guide decisions ! Potential to: ! Show which interventions are most effective and efficient ! Choose among alternatives ! Identify knowledge gaps

  5. Paradigm Shift Basic Clinical Science Research Patient Care

  6. Duke Center for Learning Health Care Experience ePRO = prototype system for PRO collection & analysis ! On-the-ground, real-time mechanism for CER, ! personalized medicine, care optimization, and quality improvement Research demonstrates system is: ! ! Easy to use and navigate ! Valid and reliable ! Appropriate for clinical trials

  7. Collection Methods

  8. Validated Questionnaires Available

  9. Interface

  10. 7 Patient Clinical Operations & Quality Research H

  11. Output for clinicians

  12. Output for clinicians

  13. Utilization

  14. In Practice Sexual Distress ! >30% of breast, GI, and lung pts in mod-severe distress ! Correlates to QOL, functional status, and symptoms ! Clinicians not addressing the issue ! Reorganized education and care " ACS funded RCT !

  15. Sequentially Linked Data New datasets sequentially added, starting at the patient level, using warehousing or federated models. The key element is patient-level linkage. ePRO Clinical & administrative Clinical trial & research Molecular & biologic

  16. Vision Patient Clinical uses - Longitudinal reporting reports at POC standardized - ROS & Decision making - Patient education data - Triggered interventions Patient Clinical Research Uses Decision - Quality reporting - CER Support - Hypothesis generation & Guidelines

  17. Evolution ! Improve visualization ! Trigger interventions & education ! Provide scorecards that include PROs as a core component ! Enable rapid learning clinic ! Embed randomization

  18. Education

  19. Evolution ! Improve visualization ! Trigger interventions & education ! Provide scorecards that include PROs as a core component ! Enable rapid learning clinic ! Embed randomization

  20. Contact Information Bradford Hirsch, MD, MBA Bradford.Hirsch@duke.edu (214) 707 -2790

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