SLIDE 1 Electronic PRO Monitoring in Duke Oncology Clinics
World Cancer Congress Presentation
Bradford Hirsch, MD, MBA
August 28rd, 2012
SLIDE 2
Medicine at Transition Point
SLIDE 3 Medicine at Transition Point
Data Driven Care
Care Redesign Quality Metrics CER
Personalized
Medicine Patient Centered Care
SLIDE 4
Evidence Based Medicine: A Paradigm Shift
! Concerted international effort to close the gap between
research and practice (CER, PM…)
! Systematic collection, synthesis, and use of evidence to
guide decisions
! Potential to: ! Show which interventions are most effective and
efficient
! Choose among alternatives ! Identify knowledge gaps
SLIDE 5
Paradigm Shift
Clinical Research Patient Care Basic Science
SLIDE 6 Duke Center for Learning Health Care Experience
!
ePRO = prototype system for PRO collection & analysis
!
On-the-ground, real-time mechanism for CER, personalized medicine, care optimization, and quality improvement
!
Research demonstrates system is: ! Easy to use and navigate ! Valid and reliable ! Appropriate for clinical trials
SLIDE 7
Collection Methods
SLIDE 8
Validated Questionnaires Available
SLIDE 9
Interface
SLIDE 10
7 H
Research Clinical Operations & Quality Patient
SLIDE 11
Output for clinicians
SLIDE 12
Output for clinicians
SLIDE 13
Utilization
SLIDE 14 In Practice
!
Sexual Distress
!
>30% of breast, GI, and lung pts in mod-severe distress
!
Correlates to QOL, functional status, and symptoms
!
Clinicians not addressing the issue
!
Reorganized education and care " ACS funded RCT
SLIDE 15 Sequentially Linked Data
ePRO
Clinical & administrative Clinical trial & research Molecular & biologic New datasets sequentially added, starting at the patient level, using warehousing or federated
- models. The key element is
patient-level linkage.
SLIDE 16 Vision Patient reports standardized data Clinical uses
at POC
- ROS & Decision making
- Patient education
- Triggered interventions
Research Uses
- Quality reporting
- CER
- Hypothesis generation
Clinical Decision Support & Guidelines
Patient
SLIDE 17
Evolution
! Improve visualization ! Trigger interventions &
education
! Provide scorecards that include
PROs as a core component
! Enable rapid learning clinic ! Embed randomization
SLIDE 18
Education
SLIDE 19
Evolution
! Improve visualization ! Trigger interventions &
education
! Provide scorecards that include
PROs as a core component
! Enable rapid learning clinic ! Embed randomization
SLIDE 20
Contact Information
Bradford Hirsch, MD, MBA Bradford.Hirsch@duke.edu (214) 707 -2790