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Depression Depression among Older among Older Adults Adults Pre va le nc e & I nte rve ntio n Stra te g ie s Definition Definition De pre ssio n is a c o mple x syndro me c o mple x c ha ra c te rize d b y mo o d disturb a nc e plus


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Depression Depression among Older among Older Adults Adults

Pre va le nc e & I nte rve ntio n Stra te g ie s

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SLIDE 2

Definition Definition

De pre ssio n is a c o mple x syndro me c o mple x c ha ra c te rize d b y mo o d disturb a nc e plus va rie ty o f c o g nitive , psyc ho lo g ic a l, a nd ve g e ta tive disturb a nc e s

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Epidemiology of Depression Epidemiology of Depression

  • Me n: 5-12%
  • Wo me n: 10-25%
  • Pre va le nc e 1-2% in e lde rly
  • 6-10% in Prima ry Ca re se tting
  • 12-20% in Nursing ho me se tting
  • 11-45% in I

npa tie nt se tting

  • >40% of outpt. Psyc hiatr

y c linic and inpt. psyc hiatr y

  • Pe a k a g e o f o nse t 3rd de c a de
  • L

a te -life de pre ssio n: se c o nda ry to va sc ula r e tio lo g y

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SLIDE 4

Simon GE, et al. N Engl J Med. 1999;341(18):1329-1335.

Depression Depression – – the physical presentation the physical presentation

In primary care, physical symptoms are often the chief complaint in depressed patients

N = 1146 Primary care patients with major depression

In a New England Journal of Medicine study, 69% of diagnosed depressed patients reported unexplained physical symptoms as their chief compliant1

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SLIDE 5

Depression in Elderly Depression in Elderly

  • NOT

a no rma l pa rt o f a g ing

  • 2 millio n Ame ric a ns o ve r a g e

65 ha ve de pre ssive illne ss

  • Sub -syndro ma l de pre ssio n

inc re a se s the risk o f de ve lo ping de pre ssio n

  • L

e a ds to e a rly re la pse a nd c hro nic ity

  • Ofte n c o -o c c urs with o the r

se rio us illne sse s

  • Unde r-dia g no se d a nd unde r-

tre a te d

  • Suic ide ra te s in the e lde rly

a re the hig he st o f a ny a g e g ro up.

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SLIDE 6

Facts in Elderly Facts in Elderly

  • Only 11 pe rc e nt in c o mmunity

re c e ive a de q ua te a ntide pre ssa nt tre a tme nt

  • T

he dire c t a nd indire c t c o sts – $43 b illio n e a c h ye a r

  • L

a te life de pre ssio n is pa rtic ula rly c o stly b e c a use o f the e xc e ss disa b ility tha t it c a use s a nd its de le te rio us inte ra c tio n with physic a l he a lth

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SLIDE 7

Etiology Etiology

  • Bio lo g ic a l fa c to rs
  • So c ia l fa c to rs
  • Psyc ho lo g ic a l fa c to rs
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SLIDE 8

Biological factors Biological factors

  • Ge ne tic
  • Hig h pre va le nc e in first de g re e re la tive s
  • Hig h c o nc o rda nc e with mo no zyg o tic twins
  • Sho rt a lle le o f se ro to nin tra nspo rte d g e ne
  • Me dic a l I

llne ss:

  • Pa rkinso n's, Alzhe ime r's, c a nc e r, dia b e te s o r

stro ke

  • Va sc ula r c ha ng e s in the b ra in
  • Chro nic o r se ve re pa in
  • Pre vio us histo ry o f de pre ssio n
  • Sub sta nc e a b use
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SLIDE 9

Social factors Social factors

  • L
  • ne line ss, iso la tio n
  • Re c e nt b e re a ve me nt
  • L

a c k o f a suppo rtive so c ia l ne two rk

  • De c re a se d mo b ility
  • Due to illne ss o r lo ss o f driving privile g e s
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SLIDE 10

Psychological factors Psychological factors

  • T

ra uma tic e xpe rie nc e s

  • Ab use
  • Da ma g e to b o dy ima g e
  • F

e a r o f de a th

  • F

rustra tio n with me mo ry lo ss

  • Ro le tra nsitio ns
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Common precipitants Common precipitants

  • Arg ume nts with frie nds/ re la tive s
  • Re je c tio n o r a b a ndo nme nt
  • De a th o r ma jo r illne ss o f lo ve d o ne
  • L
  • ss o f pe t
  • Annive rsa ry o f a (-) e ve nt
  • Ma jo r me dic a l illne ss o r a g e -re la te d

de te rio ra tio n

  • Stre ssful e ve nt a t wo rk
  • Me dic a tio n No nc o mplia nc e
  • Sub sta nc e use
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SLIDE 12

Assessment Assessment

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SLIDE 13

Clinical Features Clinical Features

  • DSM I

V-T R c rite ria

  • Multiple c rite ria (>=5) sho uld b e

pre se nt fo r a t le a st two we e ks

  • Must b e a c ha ng e fro m pre vio us

func tio ning

  • Pre se nc e o f de c re a se d inte re st o r

lo w/ de pre sse d mo o d is a must fe a ture

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SLIDE 14

Diagnostic Criteria Diagnostic Criteria

  • Sle e p disturb a nc e : de c re a se d o r

inc re a se d

  • Inte re st o r ple a sure *: de c re a se d
  • Guilt o r fe e ling wo rthle ss
  • Mo o d* : susta ine d lo w o r de pre sse d
  • Ene rg y lo ss o r fa tig ue
  • Co nc e ntra tio n pro b le ms o r pro b le ms with

me mo ry

  • Appe tite disturb a nc e , we ig ht lo ss o r g a in
  • Psyc ho mo to r a g ita tio n o r re ta rda tio n
  • Suic ida l ide a tio n, tho ug hts o f de a th
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Considerations in Elder Depression Considerations in Elder Depression

  • Une xpla ine d o r a g g ra va te d a c he s a nd pa ins
  • Ho pe le ssne ss
  • He lple ssne ss
  • Anxie ty a nd wo rrie s
  • Me mo ry pro b le ms
  • L
  • ss o f fe e ling o f ple a sure
  • Slo we d mo ve me nt
  • I

rrita b ility

  • L

a c k o f inte re st in pe rso na l c a re (skipping me a ls, fo rg e tting me dic a tio ns, ne g le c ting pe rso na l hyg ie ne )

  • So c ia l Withdra wa l
  • I

nc re a se d use o f a lc o ho l o r o the r drug s

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MINOR Depression MINOR Depression

  • Also kno wn a s
  • sub syndro ma l de pre ssio n
  • sub c linic a l de pre ssio n
  • mild de pre ssio n
  • 2 - 4 time s mo re

c o mmo n tha n ma jo r de pre ssio n

  • Asso c ia te d with:
  • sub se q ue nt ma jo r de pre ssio n
  • g re a te r use o f he a lth

se rvic e s

  • re duc e d physic a l, so c ia l

func tio ning

  • lo ss o f q ua lity o f life
  • Re spo nds to same

tre atme nts!

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SLIDE 17

SUICIDE: DON SUICIDE: DON’ ’T FORGET T FORGET

  • Ask a b o ut
  • suic ida l ide a tio n
  • inte nt
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SLIDE 18

Suicide risk in elderly Suicide risk in elderly

  • Ve ry I

mpo rta nt, E a sy to miss

  • Alwa ys a sk
  • F

ire a rms a t ho me

  • Ma ny o lde r a dults who c o mmit suic ide ha ve visite d

a prima ry c a re physic ia n ve ry c lo se to the time o f the suic ide

  • 20 pe rc e nt o n the sa me da y
  • 40 pe rc e nt within o ne we e k – o f the

suic ide

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SLIDE 19

Suicide risk in elderly Suicide risk in elderly

  • Suic ide s twic e a s c o mmo n a s ho mic ide s
  • 12% o f the po pula tio n is e lde rly, the y a c c o unt fo r

20% o f the 30,000 suic ide s/ yr

  • Olde r pa tie nts ma ke 2 to 4 a tte mpts pe r c o mple te d

suic ide , yo ung e r pa tie nts ma ke 100 to 200 a tte mpts pe r c o mple tio n

  • Whe n the y de c ide - the y a re se rio us
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SLIDE 20

Los Angeles County Attempted Los Angeles County Attempted and Completed Suicides, 2008 and Completed Suicides, 2008

(rates per 100,000) (rates per 100,000)

LA Co Dept of Public Health, Injury & Violence Prevention Program (Ma

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Assessment for suicide risk: Assessment for suicide risk:

S- Ma le Se x A- Ag e (yo ung / e lde rly) D- De pre ssio n P- Pre vio us a tte mpts E- E

T OH

R- Re a lity te sting (I

mpa ire d)

S- So c ia l suppo rt (la c k o f) O- Org a nize d pla n N- No spo use S- Sic kne ss

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Geriatric Depression Scale Geriatric Depression Scale

Cho o se the b e st a nswe r fo r ho w yo u ha ve fe lt o ve r the pa st we e k:

  • 1. Are yo u b a sic a lly sa tisfie d with yo ur life ? YE

S / NO

  • 2. Ha ve yo u dro ppe d ma ny o f yo ur a c tivitie s a nd inte re sts? YE

S / NO

  • 3. Do yo u fe e l tha t yo ur life is e mpty? YE

S / NO

  • 4. Do yo u o fte n g e t b o re d? YE

S / NO

  • 5. Are yo u in g o o d spirits mo st o f the time ? YE

S / NO

  • 6. Are yo u a fra id tha t so me thing b a d is g o ing to ha ppe n to yo u? YE

S / NO

  • 7. Do yo u fe e l ha ppy mo st o f the time ? YE

S / NO

  • 8. Do yo u o fte n fe e l he lple ss? YE

S / NO

  • 9. Do yo u pre fe r to sta y ho me , ra the r tha n g o ing o ut, do ing ne w thing s?

YE S / NO

  • 10. Do yo u fe e l yo u ha ve mo re pro b le ms with me mo ry tha n mo st?

YE S / NO

  • 11. Do yo u think it is wo nde rful to b e a live no w? YE

S / NO

  • 12. Do yo u fe e l pre tty wo rthle ss the wa y yo u a re no w? YE

S / NO

  • 13. Do yo u fe e l full o f e ne rg y? YE

S / NO

  • 14. Do yo u fe e l tha t yo ur situa tio n is ho pe le ss? YE

S / NO

  • 15. Do yo u think tha t mo st pe o ple a re b e tte r o ff tha n yo u a re ? YE

S / NO

*Unde rline d ite ms c o nstitute the fo ur ite m sc a le

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SLIDE 24
  • I

nto xic a tio n a nd/ o r withdra wa l fro m c e rta in sub sta nc e s c a n le a d to de pre ssive sympto ms.

  • I

f sympto ms a re sig nific a nt e no ug h, the y ma y b e c ha ra c te rize d a s a sub sta nc e -induc e d mo o d diso rde r.

  • Drug -induc e d sympto ms c a n la st a s lo ng a s

sub sta nc e s a re use d a nd ma y o r ma y no t impro ve with a b stine nc e .

  • De pre ssive sympto ms c a n ling e r fo r 3 to 6 mo nths

a fte r a b stine nc e a nd must b e tre a te d in c o unse ling .

Substance Use & Depressive Symptoms Substance Use & Depressive Symptoms

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SLIDE 25
  • Sub sta nc e use , a b use , o r de pe nde nc e c a n c a use

de pre ssive sympto ms to wo rse n a nd c o mplic a te re c o ve ry fro m a de pre ssive illne ss.

  • T

he se e ffe c ts ma y a lso inte rfe re with a c lie nt's re spo nse to me dic a tio ns o r o the r the ra pe utic inte rve ntio ns.

  • De pre ssio n a nd ho pe le ssne ss, c o mb ine d with

a lc o ho l a nd/ o r drug use , ma y a lso inc re a se the risk fo r thinking a b o ut, pla nning , o r a c ting o n suic ida l tho ug hts.

Substance Use & Depressive Symptoms Substance Use & Depressive Symptoms

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SLIDE 26

Substance Use & Depressive Symptoms Substance Use & Depressive Symptoms

Substance Associated Depressive Symptoms Intoxication Withdrawal Chronic Use Alcohol Depressed mood, anxiety, poor appetite, poor concentration, insomnia, restlessness, paranoia and psychosis Depressed mood and other depressive symptoms Opioids Low energy, low appetite, poor concentration Depressed mood, fatigue, low appetite, irritability, anxiety, insomnia, poor concentration Depressed mood and other depressive symptoms

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Substance Associated Depressive Symptoms Intoxication Withdrawal Chronic Use Cocaine and stimulants Anxiety, low appetite, insomnia, paranoia and psychosis Depressed mood, increased sleep, increased appetite, anhedonia, loss of interest, poor concentration suicidal thoughts Depressed mood and other depressive symptoms Cannabis Anxiety, apathy, increased appetite Anxiety, irritability Low motivation, apathy Sedative‐ hypnotics Fatigue, increased sleep, apathy Anxiety, low mood, restlessness, paranoia and psychosis Depressed mood, poor memory

Substance Use & Depressive Symptoms Substance Use & Depressive Symptoms

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SLIDE 28

Psychotherapy Psychotherapy

  • Ve ry he lpful in mild to mo de ra te de pre ssio n
  • Re spo nse time slo we r
  • Re la pse le ss fre q ue nt
  • CBT
  • As e ffe c tive a s a ntide pre ssa nts
  • I

PT

mo re e ffe c tive tha n a ntide pre ssa nts in tre a ting mo o d suic ida l ide a tio ns, a nd la c k o f inte re st, whe re a s a ntide pre ssa nts a re mo re e ffe c tive fo r a ppe tite a nd sle e p disturb a nc e s

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SLIDE 29

Empirical Review: CBT Empirical Review: CBT

Co g nitive Be ha vio r T he ra py (CBT ) is a n a c tive , dire c tive time -limite d a nd struc ture d pro b le m-so lving tre a tme nt a ppro a c h who se prima ry a im is sympto m re duc tio n (L a idla w e t al. 2003). E mpiric a l e vide nc e sug g e sts tha t CBT is a n e ffic a c io us tre a tme nt fo r la te life de pre ssio n.

R e c omme nde d te xts: L

a idla w e t a l, 2003 a nd Ga lla g he r-T ho mpso n, Ste ffe n, & T ho mpso n (2008) Ha ndb o o k o f Co g nitive a nd Be ha vio ura l T he ra pie s.

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Empirical Review: IPT Empirical Review: IPT

Inte r pe r sonal psyc hothe r apy (IPT ) is

a sho rt-te rm fo c usse d tre a tme nt pro g ra m fo r de pre ssio n (Hinric hse n & E me ry, 2005). I PT fo c use s o n 4 ma in pro b le m a re a s in its tre a tme nt a ppro a c h to de pre ssio n, the se a re : (i) g rie f; (ii) inte rpe rso na l dispute s (iii) ro le tra nsitio ns a nd (iv) inte rpe rso na l de fic its (K a re l & Hinric hse n, 2000)

R e c omme nde d te xt: Hinric hse n, G.

& Clo ug he rty, K . (2006) I nte rpe rso na l Psyc ho the ra py fo r de pre sse d o lde r a dults.

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SLIDE 31

How is Psychotherapy Different How is Psychotherapy Different with Older People? with Older People?

  • Chro nic ity a nd life time histo ry
  • f distre ss
  • De c isio ns ha ve b e e n ma de

a nd live d with

  • Physic a l illne sse s with

Psyc ho lo g ic a l Co nse q ue nc e s

  • L
  • ss e xpe rie nc e s a nd

e xpe rie nc e s o f a g ing

  • Diffe re nt va lue syste ms
  • Olde r pe o ple do n’ t ide ntify

the mse lve s a s OP, so ma yb e so me time s its no t diffe re nt!

Sadavoy talks about the 5 Cs of psychogeriatrics:

  • Chronicity,
  • Complexity,
  • Comorbidity,
  • Continuity &
  • Context
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CBT and the Demographic Context CBT and the Demographic Context

T he c ur r e nt e vide nc e base for CBT with Olde r Pe ople is r e asonably str

  • ng and matur

e BUT

In psychological treatment models there are very few specific frameworks to characterize the experience of older people who develop depression Maybe it is time to develop more age specific models of CBT for older people (Laidlaw & Pachana, 2009), and consider new targets for CBT such as attitudes to ageing and wisdom enhancement (Laidlaw, 2010) Wisdom is one of the few positive attributes associated with ageing and may enhance outcome for chronic depression

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IMPACT: Problem Solving Therapy IMPACT: Problem Solving Therapy

  • 1. Cla rifying a nd de fining the pro b le m
  • 2. E

sta b lishing o b je c tive a c hie va b le g o a l

  • 3. So lutio n a lte rna tive s: Bra insto rming
  • 4. De c isio n g uide line s: Pro s a nd Co ns
  • 5. Cho o sing the pre fe rre d so lutio n(s)
  • 6. I

mple me nting the so lutio n(s)

  • 7. E

va lua ting the o utc o me

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SLIDE 34

Importance of Pleasant Activities Importance of Pleasant Activities

  • Whe n pe o ple g e t de pre sse d the y do n’ t fe e l up to

do ing the kinds o f thing s the y typic a lly e njo y.

  • By do ing fe we r e njo ya b le thing s the y b e g in to fe e l

e ve n wo rse .

  • As the y fe e l wo rse , the y do e ve n le ss, a nd g e t

c a ug ht up in a vic io us c yc le o f do ing le ss a nd le ss a nd fe e ling wo rse a nd wo rse .

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SLIDE 35

Depressive Thought Patterns Depressive Thought Patterns

  • L
  • o k fo r pa rtic ula r tho ug ht pa tte rns suc h a s b la c k

a nd white thinking , o ve rg e ne ra lizing , c a ta stro phizing a nd pe rso na lizing .

  • Wo rk o n ide ntifying c o unte r tho ug hts to b a la nc e

de pre ssive tho ug ht pa tte rns.

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The Stages of Grief The Stages of Grief

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Processing Grief Processing Grief

  • Re c o gnize whe n a c lie nt has signific ant unre so lve d

grie f.

  • E

duc ate abo ut grie f.

  • E

xplo re the c lie nt's e xpe rie nc e with grie f.

  • Cre ate safe ty fo r e xpre ssing fe e lings.
  • F

ac ilitate grie ving.

  • Ge t c lo sure o n e ve nts that pre c ipitate d the grie f.
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SLIDE 38

Contact Information Contact Information

  • T

ho ma s E . F re e se , PhD

  • tfre e se @ me dne t.uc la .e du
  • Mitc he ll K

a rno , PhD

  • MPK

a rno @ me dne t.uc la .e du

www.uc la isa p.o rg / c o d