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Department of Oncology Radiochemistry
Martin Christlieb
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Department of Oncology Radiochemistry Martin Christlieb Page 1 - - PowerPoint PPT Presentation
Department of Oncology Radiochemistry Martin Christlieb Page 1 - - PowerPoint PPT Presentation
Department of Oncology Radiochemistry Martin Christlieb Page 1 Onc ? Page 2 Page 3 Dividing out of control Page 4 Page 4 Page 5 Department of Oncology Imaging Images of protein Page 7 Department of Oncology Chemistry Professor
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Dividing out of control
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Department of Oncology Imaging
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Images of protein
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Department of Oncology Chemistry
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Professor Veronique Gouverneur
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N N O2N OH OH
18F
N N O2N O S O OH O
F-MISO
NaF – 15 mins
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Starting material Desired product
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SM P k =
@ t = 0
20 40 60 80 100 120 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Yield
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Department of Oncology Radioactivity
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Decayed atoms
Starting material
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D SM
j =
@ t = 0
20 40 60 80 100 120 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Remaining SM
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Department of Oncology Radiochemistry
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Starting material Desired product
Decayed atoms
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SM P D k = j =
20 40 60 80 100 120 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Chart Title
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Designing a hot synthesis
k = j k = 2j k = 100j
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N N O2N OH OH
18F
N N O2N O S O OH O
F-MISO
NaF – 15 mins
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