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Foundations of Global Health Child Health Developed by Christy Ottendorfer. Updated by C. McGuire-Wolfe, 2012 Learning Objectives Identify key child health measures Understand most important causes of child illness and death


  1. Foundations of Global Health Child Health Developed by Christy Ottendorfer. Updated by C. McGuire-Wolfe, 2012

  2. Learning Objectives • Identify key child health measures • Understand most important causes of child illness and death • Describe the most cost-effective interventions • Describe some examples of successful initiatives • Discuss some challenges of further enhancing health of children 2 2

  3. Importance of Child Health • 7.6 million children die every year before their fifth birthday • Many of these deaths are preventable • Children are very vulnerable • Child health is linked with poverty • Little progress has been made in some parts of the world 3

  4. Child Mortality Rate • Probability that a child born will die before reaching age 5 , using current age-specific mortality rates in pop • Reflection of country’s health care system, poverty & inadequacy of nutrition 4

  5. Global Under 5 Deaths • Over 90% of deaths in 42 low or middle income countries • ½ of these deaths occur in 5 countries: – India – Nigeria – DRC – Pakistan – China 5 http://www.unicef.org/media/files/UNICEF_Child_mortality_for_web_0831.pdf

  6. Burden of Child Mortality • Sub-Saharan Africa • Southern Asia As under-five mortality rates have fallen more sharply elsewhere, the disparity between Sub- Saharan Africa & S. Asia and the rest of the world has increased. http://www.unicef.org/media/files/ 6 UNICEF_Child_mortality_for_web_0831.pdf

  7. Under 5 Mortality Rates http://www.unicef.org/media/files/UNICEF_Child_mortality_for_web_0831.pdf 7

  8. Causes Under 5 Death • Majority occur in neonatal period • Infectious diseases significant contribution to mortality 8

  9. Risk Factors • Poverty • Rural areas • Lack of maternal education http://www.unicef.org/media/files 9 /UNICEF_Child_mortality_for_web_0831.pdf

  10. Global Hunger Index Map http://www.ifpri.org/sites/default/files/publications/ghi11poster.pdf 10

  11. Key Terms • Perinatal – 22 weeks (gestation) to first week/life • Neonatal - first month of life • Infant - first year of life • Under-five - children 0 to 4 11

  12. Risk Factors for Neonatal, Infant & Child Deaths • Poverty • Inadequate nutrition • Educational status of mother • Poor access to safe water and sanitation , health services, and education • Family income • Malaria • HIV 12

  13. Impact of Preterm Birth • Preterm: birth at < 37 completed weeks – 12.9 million babies worldwide – 1 million neonatal deaths – 28% of neonatal deaths are due to preterm birth • Major determinant of neonatal mortality and morbidity • Burden in Africa and Asia – 85% of preterm births • Rates increasing globally, including developed countries. 13

  14. Impact of Pre-Term Birth • Long-term adverse consequences for health – Higher rates of cerebral palsy – Sensory deficits – Learning disabilities – Respiratory illnesses • Morbidity results with enormous physical, psychological, economic costs – In US, medical and educational expenditure & lost productivity = >$26.2 billion 14

  15. Preterm Birth Map, 2009 15

  16. Low Birth Weight • Born less than 5 lbs, 8 oz • Increased risk for serious health problems as newborns, lasting disabilities and even death • Poor nutritional status of mother, teenagers that are still growing at higher risk for low birth weight babies 16

  17. Perinatal Deaths & Antenatal Care 17

  18. Antenatal Care 18

  19. 19

  20. Causes of Neonatal Deaths 20

  21. First Month Stats • Most maternal & neonatal deaths rapidly occur – 75% of neonatal deaths occur during first week – 25 – 45% in first 24 hours • No skilled care during birth: 47% of all mothers and newborns in developing countries • 72% of all babies born outside hospital do not receive any postnatal care 21

  22. Neonatal Deaths http://cherg.org/main.html 22

  23. 23

  24. Interventions • Basic standard of care not universally available • Neonatal care important factor • Educate moms to exclusively breastfeed, keep baby warm, no baths w/in 24 hours • Simple treatments to prevent infection 24

  25. One Example: Human Incubators • Problem: Incubator shortage in developing countries • Solution: Kangaroo Mother Care to warm babies 25

  26. Infant Mortality Rate • Number of children born in a year who die before first birthday by total number of children born • # child deaths < 1 year x 1000 = IMR # children born • Indicator of socioeconomic development, hygienic conditions, overall health of population (health care conditions) • Easy to measure • Strongly correlated with adult mortality Source: WHO/HPR/TDR/Crump 26

  27. Infant Mortality Rates Map 27 http://data.worldbank.org/indicator/SP.DYN.IMRT.IN/countries?display=map

  28. US Infant Deaths Decline 28

  29. http://www.who.int/gho/child_health/mortality/neonatal_infant/en/index.html

  30. Significant Progress Since 1960 • Child death rates decline due to improved basic medical care, nutrient fortification, vaccines 30

  31. Child Mortality Rate Progress 31

  32. 32

  33. Under 5 Mortality Map 33

  34. MDG 4 http://www.unicef.org/media/files/UNICEF_Child_mortality_for_web_0831.pdf 34

  35. MDG 4 Progress http://www.who.int/gho/child_health/en / 35

  36. 36

  37. Newborn Asphyxia • Failure of a newborn to initiate and sustain breathing within 1 min at birth • Causes 20% of neonatal deaths • WHO estimates 4-9 million cases occur each year – Over 1 million newborns that survive develop long term problems – Cerebral palsy, mental retardation, speaking, hearing, visual & learning disabilities • Newborn resuscitation programs now used to educate providers in developing world 37

  38. Smoking & Child Health • Smoking during pregnancy 2x more likely to have premature rupture of membranes, placental abruption, placenta previa • Babies born to women smokers: – 30% higher odds born prematurely – More likely born with low birth weight – Weigh less than “non - smoking” babies – Up to 3x more likely to die of Sudden Infant Death Syndrome (SIDS) • Children exposed to secondhand smoke at increased risk for: – Bronchitis, pneumonia – Ear infections – Severe asthma 38

  39. Pneumonia • Pneumonia kills more children than any other infectious illness • Over 2 million children deaths each year – Nearly 1 in 5 under-five deaths from pneumonia • Common symptoms in children & infants: – Rapid or difficult breathing – Cough – Fever & chills – Headaches – Loss of appetite – Wheezing 39

  40. Common Causes • Bacterial infections with Streptococcus pneumoniae or Heamophilus influenzae typically found in developing world 40

  41. Stop Pneumonia • Vaccination • Case management • Diagnosis by symptoms • Antibiotics – Very inexpensive, costing less than a dollar per dose – Yet, only 1 of every 5 children with signs of pneumonia receives antibiotics • Oxygen therapy 41

  42. Tetanus • Clostridium tetani is serious bacterial disease that produces neurotoxin • Bacterial spores ubiquitous worldwide & found in soil • When introduced into body, bacteria produces toxin • Leads to painful tightening of muscles all over body, including jaw muscles (lock jaw), severe muscle spasms, difficulty breathing, and death – Death in 1 out of 10 cases • Vaccine is available (DTaP, DT, Td) 42

  43. Tetanus Elimination • In 1988, 787,000 newborns died of neonatal tetanus • By 2004, still 128,000 deaths despite World Health Assembly attempts to prioritize this disease • Maternal & Neonatal Tetanus (MNT) Elimination program – Immunize pregnant women during antenatal care contacts – If not previously vaccinated, a total of five doses is recommended – Two doses one month apart in first pregnancy – One dose in every subsequent pregnancy 43

  44. 44

  45. Child Health Care Delivery 45

  46. Table 10-5 46

  47. Key Challenges & Interventions • Critical child health interventions • Community-based approaches to improving child health • Integrated management of childhood illness (IMCI) • Nutrition of women, pregnant women, and children from conception to two years • Exclusive breastfeeding for six months • Continuum of care for newborn - keep warm, avoid neonatal tetanus, and treat pneumonia • Immunization 47

  48. Practice Questions • Where do the majority of childhood deaths occur? • Define perinatal, neonatal, infant, under five? • Name 3 risk factors contribute to childhood illness/death. • Name 3 long term consequences of preterm or low birth weight babies. • Name 5 interventions that can lower neonatal deaths. • What demographic factors are linked to under five mortality rates? • What regions are on track & off-track to meet MDG4 by 2015? • Describe 3 selected childhood illnesses (asphyxia, pneumonia, tetanus). 48

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