SLIDE 1
heterosexual but no homosexual exposure. He did not have any mucosal involvement, haemoptysis, haemetemesis and malena. He gave no history of blood transfusion or intravenous drug abuse. On general examination patient had cachectic look. Vital parameters were stable. Systemic examinations were normal except mild
- hepatospleenomegaly. Cutaneous examination
revealed discrete bilateral assymetricalnontender skin colored nodular lesions with some of them showing violaceoushue. Bilateral nontender mobile non matted soft cervical lymphadenopathy. With a clinical differential diagnosis of Kaposi sarcoma and Bacillary angiomatosis, we referred patient to the Integrated Counseling Testing Centre (ICTC) for HIV testing and was for first time diagnosed as HIV I Reactive .Absolute CD 4 count was 270.00 cells/cu mm. Other laboratory investigations revealed Haemoglobin of 9.5 gm/dl, Total white blood cell count of 7,000 cells / mm3 and a differential count of Polymorphs - 47%, Lymphocytes - 43%, Monocytes - 02% & Eosinophils - 08%. Liver and Renal function tests were within normal reference range. Serology for HBsAg and RPR were non-reactive. Radiograph chest was normal. Sputum for acid fast bacilli was
- negative. Skin biopsy report (Fig. 5) revealed
proliferation of thin walled capillaries, along the blood vessels of superficial plexuses. The capillaries were arranged in a clustered pattern and could be seen as rounded spaces filled with red blood cells,
VJIM Volume 20 January 2016 64 Vidarbha Journal of Internal Medicine Volume 20 January 2016
A Varied Presentation of Kaposi’s Sarcoma
1 2 3 4
Mukhi J , Shaikh W N , Tirpude B , Singh R P
Case Report
Introduction : Kaposi’s sarcoma (KS) is a multifocal cutaneous and extra cutaneous vascular proliferative disorder. KS was initially described by the Hungarian dermatologist, Morris Kaposi in 1872. There are four recognized clinical subsets of KS-Classical, Endemic (African), KS associated with non-HIV induced immunosuppression and with HIV infection (epidemic). HIV-associated KS was first recognized in 1979 when an epidemic of KS was identified in the homosexual community in New York.1 The World Health Organization (WHO) clinical staging for HIV/AIDS recognizes KS as an AIDS-defining illness. In India, there are only a few cases of HIV-associated KS in published literature. So we wish to report this case due to rarity of its presentation. Case Report : A 65 year old male, farmer by occupation, resident
- f Chhindwara (MP), presented with multiple skin
colored nodules over scalp (Fig. 1), face (Fig. 2), right arm (Fig. 3) and trunk (Fig. 4) since last 7
- months. He had history of multiple unprotected
ABSTRACT Kaposi’s sarcoma (KS) is a multifocal cutaneous and extra cutaneous vascular proliferative disorder. In India, there are only a few cases of HIV-associated KS in published literature. A 65-year-old married man presented with asymptomatic elevated skin lesions over the scalp, face, right arm & trunk with duration of seven months. Skin biopsy showed proliferation of thin walled capillaries with formation of slit like spaces, spindle cell proliferation, abundant extravasation of RBCs and moderately dense inflammatory infiltrate in the dermis. Thus, a clinical diagnosis of cutaneous KS was confirmed. On testing with ELISA for HIV, the patient was for the first time diagnosed as HIV I
- reactive. So we wish to report this case due to rarity of its presentation.
Key Words : HIV, Kaposi Sarcoma, Cutaneous
1 2 4
Associate Professor, Resident, Professor
- Dept. of Skin & Venereology, GMC, Nagpur
- 3Asso. Professor Surgery IGGMC, Nagpur
Address for Correspondence -
- Dr. Jayesh Mukhi