Can clinical trials address the realities of disease prevalence data? - - PowerPoint PPT Presentation

can clinical trials address the realities of disease
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Can clinical trials address the realities of disease prevalence data? - - PowerPoint PPT Presentation

Can clinical trials address the realities of disease prevalence data? 1 Examples of Variability - Considerations for Study Sample Relevant Co-morbidities Group differences Location Place Individual Factors American Journal of


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Can clinical trials address the realities of disease prevalence data?

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American Journal of Public Health: April 2010, Vol. 100, No. S1: S72–S80

Examples of Variability - Considerations for Study Sample Relevant Co-morbidities Group differences

Stratifying key variables to identify important subgroups of patients who might differentially benefit from treatment Individual Factors Location “Place”

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I f it were not for the great variability among individuals, medicine might as well be a science and not an art. —Sir William Osler, The Principles and Practice of Medicine 1892