Analysis of Opioid Overdoses and Naloxone Standing Orders in New - - PowerPoint PPT Presentation

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Analysis of Opioid Overdoses and Naloxone Standing Orders in New - - PowerPoint PPT Presentation

EMS Geo-referenced Data Analysis of Opioid Overdoses and Naloxone Standing Orders in New Orleans Catherine R. Counts, PhD, MHA AcademyHealth Annual Research Meeting June 27, 2017 Acknowledgments New Orleans EMS Dr. Jeffrey Elder


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EMS Geo-referenced Data Analysis of Opioid Overdoses and Naloxone Standing Orders in New Orleans

Catherine R. Counts, PhD, MHA AcademyHealth Annual Research Meeting June 27, 2017

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Acknowledgments

  • New Orleans EMS
  • Dr. Jeffrey Elder
  • Medical Director
  • Carl Flores
  • Chief of EMS
  • Jordan Ehrich
  • Liaison to Information technology
  • Co-authors
  • Dr. Arthur Mora
  • Dr. Julie Hernandez

@CatherineCounts #ARM17

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Opioid Epidemic in Louisiana

  • 2009
  • 10 “heroin related” deaths
  • 2014
  • 777 drug overdose deaths
  • 16.9 per 100,000
  • 2015
  • 861 drug overdose deaths
  • 19 per 100,000
  • 12.4% increase in rate of death from 2014

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Opioid Epidemic in New Orleans

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164 92 81 13 34 4 174 211 166 48 105 18 50 100 150 200 250 Homicides Drug Related Opioids Fentanyl Cocaine Meth

Recorded Deaths Drug Present During Autopsy

Accidental Drug Related Deaths in Orleans Parish

2015 2016

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Policy & Organizational Changes

  • August 1, 2014
  • Act 392 of the 2014 Regular Legislative Session
  • First responders can administer naloxone without prescription
  • August 1, 2015
  • Act 192 of the 2015 Regular Legislative Session
  • Allows for standing orders
  • Removes risk of persecution for helping victim
  • January 2016
  • New Orleans Health Department issues standing order
  • Naloxone available for purchase at two locations in NOLA
  • June 2016
  • Naloxone available for purchase at all CVS locations in NOLA

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Objective

  • Evaluate the spatial relationship between

suspected opioid overdoses and naloxone distribution points (NDPs) in Orleans Parish

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Our Data

  • New Orleans EMS naloxone usage
  • January 1, 2015 - November 15, 2016 (N = 1839)
  • From electronic patient care reporting system
  • Excluded
  • Under 18
  • Single dose AND
  • No improvement after the injection AND
  • No other indicators of a drug overdose
  • Final sample of 1490 suspected overdoses, with

1481 known to have occurred within Orleans Parish

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Description of population

Gender N Percent Male 1124 75.4% Female 361 24.2% Unknown 5 0.3% Grand Total 1490 Race and Ethnicity N Percent New Orleans 2015** White 753 50.5% 34.3% Black 693 46.5% 59.5% Hispanic 24 1.6% 1.4% Other Race 18 1.2% 1.4% Asian 2 0.1% 3.4% Grand Total 1490 Age Average 39.9 Median 37 Maximum 91 Minimum 18

** Source: American Community Survey 2015

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Average Nearest Neighbor (ANN)

  • This spatial analysis

technique is used to describe clustering / dispersion patterns for certain events

  • ANN ratio indicates

whether the distribution is dispersed

  • Z-scores indicate how

significant the observed pattern is

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Observed Mean Distance = 108 meters Expected Mean Distance = 384 meters

  • Avg. Nearest

Neighbor Ratio = 0.28 Z score = -52

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Hotspots of all Naloxone Use

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Hotspots of Naloxone Use - Zoom

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Caucasian Hotspots of Naloxone Use

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African American Hotspots of Naloxone Use

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Description of population

Race and Ethnicity N ANN ratio Z-score Interpretation White 749 0.26

  • 38.4 Clustered (significant)

African American 688 0.29

  • 35.2 Clustered (significant)

Asian 2 2.09 2.9 Not significant Hispanic 24 0.62

  • 3.5 Not significant

Other 15 0.45

  • 4.04 Not significant

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Naloxone Distribution Points vs. EMS Naloxone Usage Hotspots

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Naloxone Distribution Points vs. EMS Naloxone Usage Hotspots - Zoom

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Limitations

  • Naloxone use doesn’t equal an overdose
  • EMS protocols
  • Provider impressions and biases
  • Strict inclusion criteria
  • Deaths may be missed
  • No data for overdoses that didn’t use 911
  • Nearest Neighbor
  • Not weighted by population, next step
  • Potentially underestimating the signficance

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Conclusions and Implications

  • Suspected overdoses occur through all

neighborhoods regardless of their socio- demographic composition

  • Strong clustering patterns suggest two victim

populations

  • EMS data is an untapped resource
  • Passive policy changes may be necessary but not

sufficient

  • Distribution points exists, but barriers present
  • Community specific interventions
  • More research required

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Future Opportunities

  • Include other first responder data
  • More socio-demographic analysis
  • Linking to naloxone dispensation data
  • Assumption that standing orders are being used
  • Evaluate barriers to access
  • Evaluate other potential distribution locations
  • Community health centers
  • Rehabilitation centers

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Appendix

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Census Tract Comparison

OD victims race Census tract White pop. Census tract African Am pop. Census tract Other race pop. Census tract Median HH income Caucasian 39.7% 53.4% 6.9% $ 11,642 African American 24.6% 69.0% 6.4% $9,556 New Orleans White 34.3% African American 59.5% Other 6.2 % Median HH income $36,964

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EMS Naloxone use by Census Tract

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EMS Geo-referenced Data Analysis of Opioid Overdoses and Naloxone Standing Orders in New Orleans

Catherine R. Counts, PhD, MHA¹ – Julie Hernandez, PhD, MA² - Arthur Mora, PhD, MHA²

¹University of Washington School of Medicine ²Tulane University School of Public Health and Tropical Medicine

Research Objective To analyze spatial distributions of opioid

  • verdoses (OODs) in Orleans Parish,

Louisiana (New Orleans) with comparisons of neighborhood demographics and proximity to naloxone distribution points (NDP) from January 1, 2015 through November 15, 2016. Study Design Local EMS provider data of all naloxone administrations for suspected OOD was used to (1) map out the exact GPS location of OODs, (2) identify clusters and hotspots for OODs throughout the city and (3) evaluate possible associations between OODs clusters and the socio-demographic characteristics of the surrounding neighborhoods, defined through Census 2010 data at the census tract level. Analysis further used the location of NDPs in New Orleans to evaluate their potential impact on OODs patterns through distance analysis. During the study period, publicly available naloxone was offered through a standing pharmacy order at all stores of a large pharmacy chain (n=13), one locally owned pharmacy and a safety net hospital retail pharmacy.

Principal Findings

EMS intervention mapping provides uniquely refined insights on OODs spatial patterns at a very large scale. OODs distribution throughout New Orleans indicates 1) an occurrence through all neighborhoods regardless of their socio-demographic composition, consistent with epidemiologic findings at the national level, and 2) strong clustering patterns possibly suggesting two OOD victim populations- residents and transients (including tourists). Physical proximity to NDPs does not seem to decrease OOD risk.

Population Studied All patients that received EMS administered naloxone were initially included (n=1839). Those that received a single dose, did not improve after the injection and had no other recorded indicators of drug overdose were excluded (n=1487). Between January 2015 and November 15, 2016, 1,487 OODs (mean=2.2 per day, range 0-11 per day) were recorded. Compared to the socio-demographic composition

  • f New Orleans’ population,

Caucasian males were

  • verrepresented among OODs
  • victims. Two-thirds of the OODs

victims were between 18 and 40 years old. These findings are consistent with epidemiologic data from national level research. Nearest neighbor analysis and hotspot mapping outlined clusters and high-risk areas. OODs were recorded throughout New Orleans neighborhoods regardless of racial or economic make-up, with the most significant concentrations recorded in and around downtown, a preferred tourist destination. Out of all OOD dispatch locations, 44.9% (n = 667) occurred less than 1 kilometer from one of the 15 naloxone delivery points in New Orleans, with 64 cases recorded less than 200 meters from an NDP. The average distance to the nearest NDP was 1.7 km and the median distance was 1.0 km. Preliminary analysis of fatal

  • verdoses indicate victims were not

further away from NDP than revived/transported patients. Conclusion Policy/Practice Implications Strengthening naloxone accessibility as a potential life-saving commodity for OOD victims may require more than passive availability strategies such as standing orders. Research suggests location-optimizing strategies targeting hotspots might help close some gaps by better accounting for diversity within the target population. As the opioid epidemic expands, further research is needed to understand additional determinants of naloxone access and use.

Figure 1: Opioid overdose hotspots overlaid by naloxone delivery points Figure 3: African American opioid overdose hotspots Figure 2: Caucasian opioid overdose hotspots

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Methods

  • Map locations of suspected overdoses
  • Identify clusters and/or hotspots
  • Compare to locations of 13 naloxone distribution

points (NDPs)

  • University Medical Center New Orleans
  • Crescent City Pharmacy
  • All CVS locations
  • Compare socio-demographics at 2010 Census Tract

level

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