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Addressing the Opioid Epidemic with Patient-Centered Research PCORI - PowerPoint PPT Presentation

Addressing the Opioid Epidemic with Patient-Centered Research PCORI Annual Meeting 2018 November 1, 2018 #PCORI2018 PCORI Portfolio: Opioid Research Els Houtsmuller, PhD Associate Director, Healthcare Delivery and Disparities


  1. Addressing the Opioid Epidemic with Patient-Centered Research PCORI Annual Meeting 2018 November 1, 2018 #PCORI2018

  2. PCORI Portfolio: Opioid Research Els Houtsmuller, PhD Associate Director, Healthcare Delivery and Disparities ehoutsmuller@pcori.org November 1, 2018

  3. Els Houtsmuller, PhD • Nothing to disclose. 3 • November 29, 2018

  4. As of October 2018, PCORI has awarded $88 million to fund 16 CER studies on Opioid Use involving 170,000 patients * * Includes target numbers of active participants and records from health databases. 4 • November 29, 2018

  5. Addressing the Opioid Epidemic: Spanning the Care Continuum Management of Prevention of Non-Opioid Treatment for Long-term Treatment Opioid Use Unsafe Prescription Options for Pain Disorder Prescribing Opioid Use 5 • November 29, 2018

  6. PCORI Targeted Funding Announcements Opioids 2016 Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Noncancer Pain $30M 2016 Clinical Strategies for Managing and Reducing Long-Term Opioid Use for Chronic Pain $40M 2017 Medication-Assisted Treatment (MAT) Delivery for Pregnant Women with Substance Use Disorders Involving Prescription Opioids and/or Heroin $16M 2018 Psychosocial Interventions with Office-Based Opioid Treatment for Opioid Use Disorder $25M 6 • November 29, 2018

  7. Addressing the Opioid Epidemic: Spanning the Care Continuum - 2 Prevention of Unsafe Prescribing 7 • November 29, 2018

  8. Prevention of unsafe prescribing Comparative Effectiveness of Probabilistic versus Patient Narrative: Enhanced Risk Communication for Pain Management Following Acute Care PI Meisel Integrating the Patient Voice into a Comparative Effectiveness Trial of Communication Strategies in the Management of Chronic Pain PI Spiegel Naturalistic Experiment Evaluating the Impact of Medicaid Treatment Reimbursement Changes on Opioid Prescribing and Patient Outcomes Among Patients with Low Back Pain PI DeBar Provider-Targeted Behavioral Interventions to Prevent Unsafe Opioid Prescribing for Acute Non-Cancer Pain in Primary Care PI Kraemer Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Non-Cancer Pain PI Franklin 8 • November 29, 2018

  9. Addressing the Opioid Epidemic: Spanning the Care Continuum - 3 Management of Non-Opioid Prevention of Long-term Treatment for Treatment High-Risk Opioid Use Disorder Prescription Opioid Options for Pain Prescribing Us Opioid Use 9 • November 29, 2018

  10. Non-opioid Treatment Options for Pain Comparative Effectiveness of Pain-Cognitive Behavioral Therapy and Chronic Pain Self-Management Within the Context of Opioid Reduction PI Darnall Treating Chronic Pain using Approaches Adapted for Patients with Limited Reading Skills PI Thorn Comparative Effectiveness RCT of Mindfulness Meditation versus Cognitive Behavioral Therapy for Opioid-Treated Chronic Low Back Pain PI Zgierska 10 • November 29, 2018

  11. Addressing the Opioid Epidemic: Spanning the Care Continuum – 4 Management of Prevention of Long-term High-Risk Prescription Prescribing Opioid Use 11 • November 29, 2018

  12. Management of Long Term Prescription Opioid use Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks PI von Korff Prescription Opioid Management in Chronic Pain Patients: A Patient-Centered Activation Intervention PI Campbell Comparative Effectiveness of Patient-Centered Strategies to Improve Pain Management and Opioid Safety for Veterans PI Krebs Integrated Health Services to Reduce Opioid Use While Managing Chronic Pain PI McCormack Comparative Effectiveness of Pain-Cognitive Behavioral Therapy and Chronic Pain Self-Management Within the Context of Opioid Reduction PI Darnall 12 • November 29, 2018

  13. Addressing the Opioid Epidemic: Spanning the Care Continuum – 5 Treatment for Prevention of Opioid Use High-Risk Disorder Prescribing 13 • November 29, 2018

  14. Treatment for Opioid Use Disorder Improving Outcomes of Opioid Addicted Prisoners with Extended Release Injectable Naltrexone Before Reentry PI Woody A Simple Large Trial of Patient-Centered Care for Opioid Use Disorders in Federally Qualified Healthcare Centers and Specialty Care Settings PI Gastfriend Comparative Effectiveness of Clinical Decision-Making Processes Required by Public Health Systems PI Mark Moms in Recovery (MORE): Defining Optimal Care for Pregnant Women and Infants PI Lord/ Goodman PATHways: Comparative Effectiveness Study of Peripartum Opioid Use Disorder in Rural Kentucky PI Critchfield 14 • November 29, 2018

  15. Learn More • www.pcori.org • info@pcori.org • #PCORI2018 15 • November 29, 2018

  16. Thank You! 16 • November 29, 2018

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