AE A-DEFECA SWISS TECH . A G E - - PDF document

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AE A-DEFECA SWISS TECH . A G E - - PDF document

N A G E L I B R E A R L AE A-DEFECA SWISS TECH . A G E B E . F A G E B E A SWISS TECH A N I I R A L & A N I


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SLIDE 1

AE

A-DEFECA

N A G E L I B R E A R L

A G E B E A . A G E B E . F

SWISS TECH

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SLIDE 2

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AE EE

A N I I R A L & A N I B A C E R I E N

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D E 2 0 0 5 0 0 P I C E

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02 03 04

D E 5 0 0 1 0 0 0 P I C E D E 1 K 1 0 K P I C E P L D E 1 0 K P I E C E SWISS TECH

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*Le e de filaion on ali en laboaoie le 20/05/2020

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Zurich, 11 May 2020

Respirator masks with or without HeiQ Viroblock. Our offer in the global Covid-19 pandemic

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Purpose

HeiQ is a textile innovator with offices in 6 countries and a global network of textile manufacturing and distribution. In view of the global coronavirus pandemic and the severe shortage of medical personal protective equipment (PPE) in many countries, we are mobilizing our global team and network to help source these essentials to help hospitals, first responders, essential services, governments and businesses. As the current pandemic is disrupting our textile industry we see it as our primary duty to contribute to swiftly returning to a status quo ante and put all our resources to help fight the global pandemic. This is not our core business, but we are trying our best to leverage one of our core competencies: a small yet global and flexible company.

2

HeiQ glbal nek

HeiQ offices & productions HeiQ brandforce HeiQ distribution partners HeiQ warehouses HeiQ research partners

As a small company we must set a price so that we cover the cost to acquire these items as well as high logistics costs in such times. The surplus, if any, would be used to compensate our team who dedicate their time to help with this initiative and secure jobs at such time of uncertainty. Learn more about HeiQ at the end of this presentation.

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SLIDE 5 3

TESTED EFFECTIVE AGAINST CORONAVIRUS

HeiQ has launched HeiQ Viroblock NPJ03, an antiviral and antibacterial textile treatment a unique combination of silver and vesicle technologies designed to significantly reduce viral and bacterial infectivity on treated surfaces.

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Technical USPs

  • Non-dangerous good: logistics

and storage convenient

  • Can be applied to all types of

fabrics and nonwovens

  • Standard continuous wet-

processing applications (padding, kiss-roll etc.)

  • Application 5% to 20% w.o.f.

HeiQ Viroblock NPJ03 antiviral textile technology

  • Effective protection against contamination and

transmission of viruses and bacteria that use textiles as a hosting surface

  • Kills bacteria and destroys viruses in minutes
  • Effective against common harmful viruses such as

influenza and coronavirus

  • Breakthrough combination of two leading HeiQ

technologies:

  • HQ registered silver technologies for antiviral and

antibacterial effect

  • HQ fatty vesicle technology as a booster that

destroys viruses

  • Harnesses the natural antiviral and antibacterial

properties of silver

4 Oekotex, Bluesign, ZDHC: pending for approval
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HeiQ Viroblock Silver component

  • Small silver particles are potent antibacterial and

antiviral agents due to high surface area to volume ratio and unique chemical and physical properties 5)

  • Small silver particles are effective against viruses,

effectively eliminating them following short exposure of isolated viruses to silver 5)

  • Silver attracts the oppositely charged viruses and

binds permanently to their sulfur groups

  • HeiQ small silver particles contribute to a broad-

spectrum of antiviral mechanisms that are not prone to inducing resistance

5 5) Stefania Galdiero . a. (2011) Silver Nanoparticles as Potential Antiviral Agents, c 2011, 16, 8894-8918. 6) Egger et. al., 2009. Antimicrobial properties of a novel silver-silica nanocomposite material. Appl. Environ. Microbiol., 75(9), pp.2973-2976. A) Transmission electron micrograph showing an amorphous silicon dioxide aggregate particle (gray structure) together with numerous supported silver metal particles (dark spots). (B) Scanning transmission electron micrograph of the structure shown in panel A, providing better contrast between the silica structure (gray) and the silver metal particles (bright spots). (C) Higher magnification of the region in panel B enclosed in a box. The silver metal particles are typically between 1 and 10 nm in diameter. 6)
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SLIDE 8

HeiQ Viroblock Vesicle component

  • HeiQ Viroblock vesicle technology

(Liposomes) works as a booster

  • The fatty spherical vesicle technology

functions by directly targeting the lipid envelope (membrane) surrounding the virus

  • The vesicle technology helps to deplete

the viral membrane of its cholesterol content thereby destroying the virus

  • The vesicles rapidly destroy the virus

through a physical contact mechanism

6 6 6

HeiQ Viroblock vesicle structure Virus

Cholesterol (lipid) envelope

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SLIDE 9

Aerosol challenge test

FFP2 face masks (untreated control vs. HeiQ Viroblock treated)

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HeiQ Viroblock FFP2 masks* show significantly (>10 times)

improved reduction in virus infectivity.

Effective against key virus types: H1N1, H5N1, H7N9, Coronavirus (229E), and RSV

* Treated with HeiQ Viroblock NPJ03 antiviral and antimicrobial treatment Log
  • g redu
duction
  • n
% redu duction
  • n
Study ID Agent Contro rol Virobl roblock
  • ck
* Contro rol Virobl roblock
  • ck
798-110 H1N1 (Human Influenza A) 3.63 5. 5.38 38 >50x >50x 99.9766% 99.9996% 798-111 H5N1 (Avian Influenza A) 2.86 4. 4.86 86 100x 100x 99.862% 99.999% 798-112 229E (Human Coronavirus) 2.90 4. 4.48 48 >30x >30x 99.874% 99.997% 798-114 H7N9 (2013 Influenza A) 1.93 4. 4.24 24 >200x >200x 98.825% 99.994% 798-115 RSV (Respiratory Syncytial Virus) 1.40 3. 3.10 10 >50x >50x 96.02% 99.92% 798-116 Mycobacterium terrae (ATCC 15755) 0.26 1. 1.98 98 >50x >50x 45.05% 98.95%