SLIDE 2 Background Background
The The cardiovascular cardiovascular system system (CVS) (CVS) is is responsible responsible for for supplying supplying oxygen
and and nutrients nutrients to to tissues tissues and and organs
.
CV CV diseases diseases are are a a major major cause cause of
death in in humans humans. .
Many Many experimental experimental studies studies have have studied studied the the mechanisms mechanisms and and therapy therapy of
the the CV CV diseases diseases the the CV CV diseases diseases
Together Together with with experimental experimental approaches, approaches, mathematical mathematical modeling modeling has has become become a a popular popular way way to to analyze analyze the the CVS CVS. .
Many Many models models have have been been published published since since the the preliminary preliminary and and basic basic model model of
Godins in in 1959 1959
Approaches Approaches include include: hemodynamic hemodynamic models models of
the vascular vascular system, system,
Approaches Approaches include include: hemodynamic hemodynamic models models of
the vascular vascular system, system, distributed distributed impedance impedance and and pulmonary pulmonary arterial arterial stress, stress, lumped lumped parameter parameter models models of
the integrated integrated CVS, CVS, hemodynamic hemodynamic monitoring monitoring models, models, etc etc.. .. In In the the last last fe fe ears ears there there ha e ha e been been important important de elopments de elopments in in
In In the the last last few few years years there there have have been been important important developments developments in in integrated integrated lumped lumped parameter parameter models models of
the circulatory circulatory and and nervous nervous control control systems systems. .
2 PASI 2011 - A. Bandoni
