SLIDE 23 Efficacy in Primary Care Outcomes Source
Randomized controlled trials of patients presenting to primary care not specifically for alcohol treatment with brief intervention for up to four sessions. The studies were culled from the literature utilizing seven data bases from 1962-2006 with data abstracted for trials that met criteria for trial quality. Meta-analysis of 22 RCTs (N=7619) Participants receiving BI had lower consumption than those in control group s/p 12 months or longer (mean difference: -38 grams/week, 95% CI: -54to- 23). Meta-regression showed little evidence of greater reduction in alcohol consumption with longer treatment exposure or among trials which were less clinically representative, Extended intervention was associated with a non- significantly greater reduction in alcohol consumption than brief intervention (mean difference=-28, 95%CI: -62 to 6 grams /week, I2=0% Kaner EFS, Dickenson HO, Beyer FR, Campbell F, Heather N, Saunders JB, Burnand B, Poenaar D. Effectiveness of brief alcohol interventions in primary care
Database of Systematic Reviews 2007, Issue 2. Art. No.:CD004148.DOI: 10.1002/14651858.CD00414 8.pub3. John Wiley & Sons,
A systematic review of the literature from 1992 through 2004 was made to identify relevant controlled trials and cost effectiveness studies was completed tin
- 2005. Clinically preventable burden (CPB)
was calculated as the product of effectiveness times the alcohol- attributable fraction of both mortality and morbidity (measured in quality –adjusted life years or QALYs), for all relevant
- conditions. Cost effectiveness from both
the societal perspective and the health system perspective was estimated. Calculated CPB was 176,000 QALYs saved over the lifetime of a birth cohort of 4,000,000, with a range in sensitivity analysis from -43% to +94%. Screening and brief counseling was cost-saving from the societal perspective and a cost- effectiveness ratio of $1755/QALY saved. Sensitivity analysis indicates that from both perspectives the service is very cost-effective and may be cost saving. Solberg LI, Maciosek MV, Edwards NM. Primary Care Intervention to reduce Alcohol Misuse, Ranking Its Health Impact and Cost
Journal of Preventive Medicine 2008; 34(2) 143- 152.e3