Propensity Analysis Major Depressive Disorder Collaborative - - PowerPoint PPT Presentation

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Feb 18, 2023 112 likes •161 views

Propensity Analysis Major Depressive Disorder Collaborative Depression Study 25 year naturalistic follow up Bias reduction in effectiveness analyses of longitudinal ordinal doses with a mixed- effects propensity adjustment

SLIDE 1

Propensity Analysis

SLIDE 2

Major Depressive Disorder

Collaborative Depression Study
25 year naturalistic follow up
Bias reduction in effectiveness analyses of

longitudinal ordinal doses with a mixed- effects propensity adjustment

Adjusts for susceptibility bias

Leon et al. Am J Psychiatry 2003; 160:727–733

SLIDE 3

Odds of Recovery from MDD Episode Compared to No Treatment

0.2 0.4 0.6 0.8 1 1.2 1.4 1.6 1.8 2 High Medium Low

Odds Ratio Controlled for propensity for treatment intensity

Intensity of Somatic Treatment

p=.002 p=.35 p=.51

Leon et al. Am J Psychiatry 2003; 160:727–733

SLIDE 4

Odds of Relapse with MDD Episode Compared to No Treatment

0.2 0.4 0.6 0.8 1 1.2 High Medium Low

Odds Ratio Controlled for propensity for treatment intensity

Intensity of Somatic Treatment

p=.009 p=.055 p=.929

Leon, Hedeker, Teres. Statist. Med. 2007; 26:110–123