Jornadas Informativa Convocatoria 2019 Reto Social 1 de H2020 - - PowerPoint PPT Presentation

Oportunidades en “Better health an care,economic growth and sustainable Health Systems”

Madrid, 17.01.2019

Juan E. Riese PhD MBA Punto Nacional de Contacto – Reto Social 1 H2020 & IMI2 Experto Nacional en el Comité de Programa Reto Social 1 Oficina de Proyectos Europeos Subdirección General de Programas Internacionales de Investigación y Relaciones Institucionales

Jornadas Informativa ‘Convocatoria 2019 Reto Social 1 de H2020’

Oportunidades convocatoria 2019 en topics BHC

Hablaremos de

1. Oportunidades en el Reto Social 1: convocatorias 2019 y 2020 2. Otras oportunidades en Salud:

1. La Iniciativa de Medicamentos Innovadores IMI 2 2. European Innovation Council -EIC

Oportunidades convocatoria 2019 en topics BHC

1. Oportunidades en el Reto Social 1: convocatorias 2019 y 2020 2. Otras oportunidades en Salud:

1. La Iniciativa de Medicamentos Innovadores IMI 2 2. European Innovation Council -EIC

Oportunidades convocatoria 2019 en topics BHC

Pilar 3 - Retos Sociales

*: Cifras en Millones de Euros

*

Oportunidades convocatoria 2019 en topics BHC

Reto Social 1 “Salud, Cambio Demográfico y Bienestar”

– Envejecimiento de la población – Ciudadanos mejor informados y mayores exigencias a los proveedores de atención médica por parte de los pacientes – Solicitud de sistemas sanitarios más personalizados y sostenibles Retos específicos: Entender mejor la salud y la enfermedad

• la medicina personalizada

La carga de las enfermedades crónicas e infecciosas Mejoras en el desarrollo de fármacos

Better Health for all

Oportunidades convocatoria 2019 en topics BHC

Premisas conv. SC1 2019

• Las ‘3 Os’: Open science, open innovation and open to the

world

• To deliver solutions for a better health for all by:

– Moving towards the effective integration of personalised medicine approaches into healthcare services and systems to the benefit of patients and citizens; – Fighting infectious diseases and the growing threat

• f

antimicrobial resistance; – Addressing the needs of the most vulnerable groups and the global increase of chronic diseases; – Decoding the role of environment – including climate change and air quality – on health and developing mitigating measures; – Exploring the digital potential for health innovation and healthcare, including the building of a 'European health research and innovation cloud'; – Stimulating innovation in the European healthcare domain and industry by exploring the application of advanced technologies, improve the health of the workforce and promote regulatory science.

Oportunidades convocatoria 2019 en topics BHC

Hacia las convocatorias de SC1 2018-2019-2020 7 prioridades repartidas en 3 áreas

Area 1. Better health and care, economic growth and sustainable health systems (Topics BHC)

• 1. Personalised medicine
• 2. Innovative health and care industry
• 3. Infectious diseases and improving global health
• 4. Innovative health and care systems – Integration of care
• 5. Decoding the role of the environment for health and well-being

Area 2. Digital transformation in health and care (Topics DTH) Area 3. Trusted digital solutions and cybersecurity in health and care (Topics TDS) Otras acciones. EIC: premios (en conv. 2020), Instrumento PYME, FTI, FET Open

Oportunidades convocatoria 2019 en topics BHC

Prioridad – Better Health and care, economic growth and sustainable health systems (I)

1.1. Personalised Medicine

• SC1-BHC-31-2019: Pilot actions to build the foundations of a human cell

atlas (3-5 M€; 3-5 projects –total 15 M€)

1.2. Innovative health and care industry

• SC1-BHC-07-2019: Regenerative medicine: from new insights to new

applications (6-8M€; 6-8 proyectos – total 50 M€)

• SC1-BHC-10-2019: Innovation Procurement: Next generation sequencing

(NGS) for routine diagnosis (9-11 M€; 3-4 proyectos – total 40 M€) PCP funding scheme

Oportunidades convocatoria 2019 en topics BHC

SC1-BHC-31-2019: Pilot actions to build the foundations

• f a human cell atlas (I)

Specific Challenge:

• To create molecular reference maps of all human cells .
• To generate data and/or develop methods for in-depth, integrated molecular analysis

and spatial resolution of single cells from complex biological systems such as human

• rgans and tissues.

Scope

• Each

pilot action should demonstrate the utility

• f

an interdisciplinary technological/biological platform to generate and integrate standardised molecular, cellular, biochemical and other data sets, characterising single cells or their nuclear components, their interactions and/or spatial location in tissues from one human

• rgan.
• Platforms supporting analysis of tissues from more than one organ are also in scope.

The primary focus should be on healthy tissues, though comparison between healthy and diseased tissues could be appropriate. Sex, age and ethnicity comparisons could also be considered.

• The projects should have a duration of two years. To ensure coherence and

communication between projects funded under this topic and with the HCA, the Commission will ensure an overall coordination mechanism between the projects.

Oportunidades convocatoria 2019 en topics BHC

SC1-BHC-31-2019: Pilot actions to build the foundations

• f a human cell atlas (II)
• The Commission considers proposals requesting a contribution from the

EU of between EUR 3 and 5 million would allow for the specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.

Expected Impact:

• Timely contribution of project results to the HCA
• Effective and sustainable biological and/or technological platforms.
• Competitive and sustainable European role in HCA
• Strong involvement of European technology SMEs
• Laying the groundwork for improving diagnosis and treatment of

disease

Oportunidades convocatoria 2019 en topics BHC

SC1-BHC-07-2019: Regenerative medicine: from new insights to new applications

Oportunidades convocatoria 2019 en topics BHC

SC1-BHC-10-2019: Innovation Procurement: Next generation sequencing (NGS) for routine diagnosis

The objective is to implement NGS in routine diagnostics for personalised medicine and scale up demand-driven innovation for healthcare systems including organizational, economical, technical and clinical aspects.

Expected Impact:

• New NGS platforms and use of NGS tests in routine diagnostics for

personalised

• medicine.
• Accepted new European standards and quality assurance schemes with

respect to NGS.

• Strengthening
• f

implementation

• f

personalised medicine and improved clinical decisions and health outcomes for the benefits of patients.

• Contribution to the sustainability of healthcare systems.
• Growth and benefit to the European industry, in particular SMEs.

Type of Action: Pre-Commercial Procurement

Oportunidades convocatoria 2019 en topics BHC

Prioridad – Better Health and care, economic growth and sustainable health systems (II)

1.3 Infectious diseases and improving global health

• SC1-BHC-13-2019: Mining big data for early detection of infectious

disease threats driven by climate change and other factors ( 12-15 M€; 2-3 proyectos – total 30 M€)

• SC1-BHC-32-2019: Towards a next generation influenza vaccine to

protect citizens worldwide – an EU-India collaboration (6-10 M€; 1-2 proyectos – total 15 M€) 1.5 Decoding the role of the environment for health and well-being

• SC1-BHC-28-2019: The Human Exposome

Project: a toolbox for assessing and addressing the impact of environment on health (8-12 M€; 4-6 proyectos – total 50 M€)

Oportunidades convocatoria 2019 en topics BHC

SC1-BHC-13-2019: Mining big data for early detection of infectious disease threats driven by climate change and other factors (I)

Specific Challenge:

• A range of factors is responsible for the (re-)emergence of infectious disease

threats, including antimicrobial resistance.

• The use of next generation sequencing combined with surveillance data,

health registries and societal data from informal/non-traditional sources (e.g. social media) holds promise for improving individual and population health. Scope: It is expected that proposals develop:

1. the technology to allow the pooling, access, analysis and sharing of relevant data, including next generation sequencing; 2. the innovative bio-informatics and modelling methodologies that enable risk modelling and mapping; and 3. the analytical tools for early warning, risk assessment and monitoring of (re-) emerging infectious disease threats.

Oportunidades convocatoria 2019 en topics BHC

SC1-BHC-13-2019: Mining big data for early detection of infectious disease threats driven by climate change and other factors (II)

• Proposals should be able to demonstrate the feasibility of such extended data mining

for the purposes outlined.

• Proposals should be transdisciplinary and ensure an integrated One Health approach by

linking data from a wide range of relevant sources depending on the infectious disease threat. Expected Impact:

• Strengthened EU preparedness to address threats from (re-)emerging infectious

disease threats, by making available the appropriate technology and tools for risk modelling and early threat detection, to support an appropriate public health response.

• Contribution to the European One Health action plan against antimicrobial resistance.
• Contribution to the digital transformation of health and care within the context of the

EU Digital Single Market.

• Contribution to achieving Sustainable Development Goal (SDG) 3 and specifically the

targets on 1) combating epidemics, and 2) strengthening capacity for early warning and response to health risks. Contribution to achieving of SDG 13 and specifically the targets on 1) integrating climate change measures into national policies, strategies and planning, and 2) improving education, awareness-raising and human and institutional capacity on climate change adaptation, impact reduction and early warning.

Oportunidades convocatoria 2019 en topics BHC

SC1-BHC-32-2019: Towards a next generation influenza vaccine to protect citizens worldwide – an EU-India collaboration (I)

Scope:

• Proposals should cover at least pre-clinical and/or early clinical research,

selecting promising vaccine candidate(s), supporting their proof of concept, showcasing new pre-clinical or clinical knowledge.

• The approach taken should include validation of one or more candidate

vaccine(s) in a human challenge model of influenza, and/or work to improve the influenza human challenge model itself.

• Proposals shall include at least three participants from India. For more

information, interested entities in India shall consult the website of the Department of Biotechnology (DBT) http://www.dbtindia.nic.in/funding- mechanism/call/# , where DBT will indicate the eligibility conditions to Indian applicants.

Oportunidades convocatoria 2019 en topics BHC

SC1-BHC-32-2019: Towards a next generation influenza vaccine to protect citizens worldwide – an EU-India collaboration (II)

Expected Impact:

• Further the development of a vaccine that could be effective against an

increased breadth of seasonal strains and/or from the outset of a large- scale influenza pandemic.

• Utilization of and/or further improvement of the human challenge

model of influenza as a tool for candidate vaccine(s) assessment.

• Contribute to the reduction of the burden of influenza outbreaks

worldwide, particularly in Europe and India.

• Specific to India, boost initiatives like the National Health Mission88

and Biopharma Mission [Innovate in India (I3)] of the Government of India by developing affordable biopharmaceuticals, including vaccines, for citizens the world over.

Oportunidades convocatoria 2019 en topics BHC

Oportunidades convocatoria 2019 en topics BHC

Topic SC1-BHC-28-2019 (cont.)

Oportunidades convocatoria 2019 en topics BHC

Coordination and Support Actions (CSA) en prioridad BHC

• SC1-HCO-01-2018-2019-2020: Actions in support of the International

Consortium for Personalised Medicine (1,5-2M€; 3 proyectos – total 8 M€ - 1 proyecto/año)

• SC1-HCO-15-2019: Support for the functioning of the Global Research

Collaboration for Infectious Disease Preparedness (GloPID-R)

Oportunidades convocatoria 2019 en topics BHC

Reglas básicas de elegibilidad y participación

• El consorcio debe estar formado formado como mínimo 3 entidades independientes

entre sí de 3 países EU o Estados Asociados.

• Inclusión de aspectos SSH (Social Sciences and Humanities): culturales, sociales, etc.
• Aspectos de género:

– Gestión del proyecto – Objeto de la I+i

• Aspectos éticos.
• Ciencia abierta, acceso abierto:

– Difusión y comunicación

• Participación de los EEUU y terceros países. Países BRICS+M no pueden recibir

financiación excepto si se menciona específicamente en el texto del topic o son necesarios para los objetivos del proyecto. ¡Atención con el Brexit!

• Solicitudes en una o dos fases.
• El presupuesto del proyecto debe ser el adecuado para poder realizar las

actividades previstas y alcanzar los objetivos fijados.

• El presupuesto en el texto de la convocatoria es normalmente indicativo.
• La duración del proyecto debe ser la adecuada para alcanzar sus objetivos

(habitualmente entre 3 -5 años).

Oportunidades convocatoria 2019 en topics BHC

Presupuesto total para las convocatorias 2019 y 2020 del SC1

• Call SC1 2018: 650,99 M€
• Call SC1 2019: 787,18 M€*
• Call SC1 2020: 697,72 M€

*: Convocatoria abierta en 2018

Oportunidades convocatoria 2019 en topics BHC

Fechas de cierre de la convocatoria 2019 del SC1 (BHC y HCO)

Topics Apertura Fecha de cierre Observaciones SC1-BHC- 07/10/13/28/31/32 26.07.2018 16.04.2019 RIA (excepto 10: PCP) HCO-01/15 26.07.2018 16.04.2019 CSA

Oportunidades convocatoria 2019 en topics BHC

Resumen de oportunidades de financiación de la I+I en Salud

*: Fuente: Comisión Europea

Oportunidades convocatoria 2019 en topics BHC

Información sobre convocatorias en: http://eu-isciii.es