Environmental and Human Health Effects Challenges of addressing - - PowerPoint PPT Presentation

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Environmental and Human Health Effects Challenges of addressing - - PowerPoint PPT Presentation

Environmental and Human Health Effects Challenges of addressing contamination of any sort 8 Environmental and Human Health Effects ! NO DATA NO PROBLEM 9 Environmental and Human Health Effects The classic four line defence 10


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Environmental and Human Health Effects

Challenges of addressing contamination of any sort

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Environmental and Human Health Effects

NO DATA NO PROBLEM

!

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Environmental and Human Health Effects

The classic four line defence

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Environmental and Human Health Effects

The classic four line defence 1. Our activities do not pollute

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Environmental and Human Health Effects

The classic four line defence 1. Our activities do not pollute 2. Our activities cause pollution, but they do not affect you

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Environmental and Human Health Effects

The classic four line defence 1. Our activities do not pollute 2. Our activities cause pollution, but they do not affect you 3. Our activities pollute the environment. But it did not hurt you

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Environmental and Human Health Effects

The classic four line defence 1. Our activities do not pollute 2. Our activities cause pollution, but they do not affect you 3. Our activities pollute the environment. But it did not hurt you 4. Our activities pollute and it hurt you. But it was not our fault

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The classic four line defence 1. Our activities do not pollute. 2. Our activities cause pollution, but they do not affect you. 3. Our activities pollute the environment. But it did not hurt you. 4. Our activities pollute and it hurt you. But it was not our fault. And if all else fails: 5. You worked at the company and caused the pollution

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Environmental and Human Health Effects

50 100 150 200 250 300 350 1980 1990 2000 2010 2020 Number of publications per year

Year

Pubmed search results for 'PFOS'

50 100 150 200 250 300 1980 1990 2000 2010 2020 Number of publications per year

Year

Pubmed search results for 'PFOA'

Emerging PFAS research

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Environmental and Human Health Effects

Global health / environment agencies agree PFASs are toxic, bioaccumulative and persistent

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Environmental and Human Health Effects

Emerging evidence for toxic effects includes:

  • affect growth, learning, behaviour of infants and

children

  • lower a woman’s chance of getting pregnant
  • interferes with the body’s natural hormones

(thyroid and cholesterol)

  • increase cholesterol levels
  • affect the immune system
  • increase the risk of cancer (kidney and testicular)

Global health / environment agencies agree PFASs are toxic, bioaccumulative and persistent

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Establishing the evidence Minimizers

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Environmental and Human Health Effects

Precautionary Principle Establishing the evidence Minimizers

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Environmental and Human Health Effects

Human studies show that increased exposure to PFOA might increase for some health effect but those studies have scientific

  • limitations. Human studies are difficult to interpret, and we cannot

be sure that PFOA caused the observed health effects.

Source: https://www.nysenate.gov/sites/default/files/alb_freed_testimony.pdf

The Minimizers

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Studies both in people and in animals have shown a link between PFOA exposure and testicular and kidney cancer. There is a distinct probability that such an association exists.

The Precautionary approach

Source: https://www.nysenate.gov/sites/default/files/alb_freed_testimony.pdf

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Working through the muddle of interpretation

§ Both of those statements are true But § History of toxic chemical research provides a clear message

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Absence of evidence should not be taken as evidence of absence

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Acceptable values for exposure subject to constant lowering over last decade — with new values only just emerging for Australia

PFAS exposure levels – no clear consensus

  • n this issue
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Environmental and Human Health Effects

http://www.health.gov.au/internet/main/publishing.nsf/content/ohp-pfas-hbgv.htm#final

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http://www.health.gov.au/internet/main/publishing.nsf/content/ohp-pfas-hbgv.htm#final

1.8

https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2018.5194

0.8

European Food Safety Authority, 13 Dec 2018

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20 ng/kg/day 20 ng/kg/day 3 ng/kg/day 2 ng/kg/day

2016 2018

https://www.atsdr.cdc.gov/mrls/mrllist.asp

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Environmental and Human Health Effects

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Environmental and Human Health Effects

German (2016) HBM I value no risk for adverse health effects

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Environmental and Human Health Effects

Key point – significant uncertainty around “safe” levels