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Circuit Paul Ricard 2760 route des hauts du Camp 83330 LE CASTELLET (France)

ZAMAR THERAPY

" Optimization of perioperative care

with cryo-thermoregulation “

What is the Zamar Therapy ?

Introduction to Zamar Therapy

Personnalized Cryo treatment that promotes accelerated healing after an operation or trauma. The system consists of 3 components:

• Zamar device to cool and circulate the fluid
• A wrap that delivers the cold therapy
• Zamar custom protocols to guide therapy
• Clinical Benefits: Significantly reduces inflammation, pain and

promotes faster recovery of mobility

• Zamar VS ice systems : The ice is rarely at the right temperature,

can be painful and requires regular changes

• The treatment is designed to apply to a number of conditions affecting

9 different parts of the body

• Each patient receives a series of sessions during their hospital stay:

before and after the operation, after physical therapy, and in the evening for pain management.

• Nurses, Physios, orthopedists and anesthesiology staff are involved in

the treatment What is the Zamar Therapy ? Why using this therapy ? How to apply this treatment ?

is a system designed to accelerate and improve patient recovery following an operation or

• trauma. Each comprehensive therapeutic treatment consists of a series of cold therapy sessions

scheduled throughout a patient's hospital stay. The system consists of 3 parts : General process

• PW CONCEPT installs the devices
• Each patient receives his own dedicated and sterile Wrap
• Sessions can be started, interrupted and resumed in any Zamar Therapy unit
• PW CONCEPT will provide training, support and documentation for hospital staff to implement the system.

Adapted et STERILE Wraps Machine Adapted Treatment Protocols

Wraps

• Direct contact with the patient's skin
• Cooled fluid circulation of the Zamar devic
• Single patient use for safety and hygiene
• Comfortable for prolonged use
• Optimized for constant temperature exchange

Zamar Protocol

• Scientifically developed processes to determine the

right temperatures

• Adapted to the type of wound, the size of the

patient and the stage of healing

• Controlled feedback for safety and therapeutic

coherence

• Medical device CE Class IIA
• Touch interface
• Controlled temperature exchange
• Precise temperature maintenance

Zamar Therapy Zamar Wrap Zamar Protocol

Why using the Zamar Therapy ?

Why use Zamar therapy ? History of cold therapy

• Cold therapy comes from ancient times and has been widely used for decades as a

physiotherapy treatment

• Cold therapy neutralizes the five signs of inflammation:
• Pain
• Heat
• Redness
• Swelling
• Loss of function
• Many studies exist on the scientific basis of cold therapy

Inconvénients de la Thérapie traditionnelle par le froid

Traditional cryo-therapy using ice or gel is impractical and inefficient

• Extreme temperatures (below 8 ° C) uncomfortable
• Risk of burns and nerve damage
• Continuous application is not possible
• Non-constant / uncontrolled temperature
• Requires a large workforce
• Constant change of ice packs or gel pack
• Not very adaptable to anatomical forms
• Diversity of clinical outcomes
• All tests use different cold conditions
• Same protocols for all patients

Benefits of the Zamar Therapy

With Zamar therapy, patients enjoy the benefits of cold therapy without the disadvantages of other alternatives

• Fluid circulation provides convection for temperature exchange
• Fluid temperatures controlled (> 8 ° C)
• Comfortable
• Direct contact with the skin
• No infectious risk
• Continuous treatments possible
• Specific wraps adapted to the treated anatomical area
• Large contact area
• Pressure uniformly applied
• Integrated Zamar protocols
• Specific temperatures for different parts of the body
• Durations adapted to different body types (S / M / L)
• Easy to use
• Almost no maintenance required

Physiological Effects of Zamar Therapy

Zamar Therapy

Reduce tissue metabolism Reduce the speed of nerve conduction

Reduce inflammation Reduce secondary damage Reduce oxygen demand Reduce sweeling Reduce heat Reduce functional impairment Reduce redness Reduce Pain

• Fewer drugs needed to fight the pain
• High pain scores
• Better range of motion at recovery
• Faster recovery and return to normal activities
• Limitation of risk of arthrofibrosis and unsightly scar

Indications and Protocols Zamar Therapy

Examples of indications

As a tool to accelerate and improve recovery processes, Zamar Therapy has applications in post-

• perative recovery, trauma and sports medicine.

The system has several wraps designed for different areas of the body.

Total knee prosthesis, corrective osteotomy, tibial plateau fracture, distal femur fracture, ACL reconstruction, arthroscopy Total hip prosthesis, cervical fracture, trochanter fracture, arthroscopy, dislocation Arthroplasty, instability / capsulitis, fracture of the humerus, arthroscopy, arthroscopic neoplasty, rotator cuff rupture, clavicle fracture, dislocation Arthrodesis, arthroplasty, calcaneal fracture, arthroscopy, fracture Arthrodesis, arthroplasty, elbow fracture, arthroscopy, stiff elbow Femur fracture, quadriceps rupture, tibia and fibula fracture Fracture of the humerus, radius, ulna Arthrodesis, fracture

Knee Hip Shoulder Ankle Elbow Arm Wrist Lower limb

Exemples de planning de traitements

Sessions should be given before and after the operation on the day of the operation and after the physiotherapy on the days of convalescence, with the option of additional pain management if necessary.

Pain management 4 hrs Immediat Post-Op 6 hrs Post-PT 2 hrs Post-PT 2 hrs Physio Physio Opération Pré-Op 1-2 hrs D 0: Opération D 1-5: Recovery EMT 1 hr

Waiting room 3 hrs

Overnight 8 hrs treatment Trauma day

2-3 hrs 2-3 hrs 2-3 hrs 2-3 hrs 2-3 hrs

Pain management 4 hrs

How to use therapy ? Presentation of the process

Waiting room 4.Full pre op session 5.Remove the Wrap

• 6. Apply the wrap after

the surgery

• 7. Start recovery

sessions (6 hrs) 8.Complete recovery session 9.Option: Pain Management(4hrs)

Day of the surgery

1.Patients informations 2.Wrap application 3.Start the pre op session (2 hrs)

Postoperative recovery days

Patient in his room

1. Post-PT recovery sessions (2 x 2 h) 2. Option: pain management sessions (2 x 4h)

Patient room Wake up room Operation room d’attente

How to use the The responsibilities of hospital staff

Roles

Surgeon

At any time :

• Know which indications benefit from cold therapy Pre-operation
• Talking to the patient during the patient's briefing
• Explain the benefits and risks Postoperative: Apply the wrap in the operating room

Anesthesist

Pre opération:

• Be aware that the patient is being treated
• Important because of the effects on the physiology of the patient

Recovery room

At any time

• Be aware of all instructions and reminders of use
• Follow the patient's progress on the treatment session checklist
• After the operation: administer a postoperative recovery session

Care Room and patient room

Main responsibilities and reminders

At any time:

• Be aware of all instructions and reminders of use
• Follow the patient's progress on the treatment session checklist
• Pre-operation: Start the preoperative session
• After the operation: Complete the postoperative recovery session.
• Administer post-PT and pain management sessions.

Distributed in exclusivity by

Circuit Paul Ricard 2760 route des hauts du Camp 83330 LE CASTELLET (France)