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1 Oxirane (ethylene oxide) YSU YSU Brevetoxin B YSU YSU 2 - PDF document

YSU YSU YSU YSU 1 Oxirane (ethylene oxide) YSU YSU Brevetoxin B YSU YSU 2 Palytoxin Palytoxin YSU YSU Mucocin YSU YSU 3 YSU YSU YSU YSU 4 YSU YSU Chapters 6 & 15 YSU YSU 5 Sequential acid base & S N 2


  1. YSU YSU YSU YSU 1

  2. Oxirane (ethylene oxide) YSU YSU Brevetoxin B YSU YSU 2

  3. Palytoxin Palytoxin YSU YSU Mucocin YSU YSU 3

  4. YSU YSU YSU YSU 4

  5. YSU YSU Chapters 6 & 15 YSU YSU 5

  6. Sequential acid ‐ base & S N 2 reactions YSU YSU Sequential protonation & S N 2 reactions YSU YSU 6

  7. O Epoxidation ‐ intermolecular O OH Cl O CH 2 Cl 2 CH Cl Substitution ‐ intramolecular OH NaOH, solvent O Br YSU YSU S N N 2 2 Control Control Similar to S N 2 reaction; stereocenters inverted YSU YSU 7

  8. S N 1 Control 1 Control YSU YSU YSU YSU 8

  9. Acid ‐ base reaction followed by S N 2 displacement YSU YSU Not covering 16 16 and 16 17 Not covering 16.16 and 16.17 YSU YSU 9

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